Understanding childhood obesity and its causes in American Samoa

CREBRF Genomics, Gestational Diabetes, and Early Life Body Size in American Samoa

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11119329

This study is looking at what causes childhood obesity in infants and young kids from American Samoa, especially how genes and metabolism play a role, so we can find ways to help them stay healthy from an early age.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11119329 on NIH RePORTER

What this research studies

This research investigates the factors contributing to childhood obesity, particularly focusing on the genetic and metabolic aspects in infants and young children from American Samoa. By utilizing metabolomics, the study aims to explore how variations in body composition, such as fat and lean mass, develop during early life. The research specifically examines the impact of a genetic variant associated with obesity and its paradoxical protective effect against diabetes. The goal is to identify early intervention opportunities to promote better health outcomes for children.

Who could benefit from this research

Good fit: Ideal candidates for participation include infants and young children from American Samoa, particularly those at risk for obesity.

Not a fit: Patients who are not from American Samoa or do not fall within the early childhood age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing childhood obesity and related health issues in Pacific Islander populations.

How similar studies have performed: Previous research has shown promising results in understanding genetic factors related to obesity, but this specific approach focusing on Pacific Islanders is relatively novel.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.