Comparing strict and permissive thresholds for treating gestational diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of different thresholds for initiating and adjusting pharmacotherapy in patients with gestational diabetes (GDM). Participants will be assigned to either a strict threshold group, targeting blood glucose levels between 65-120 mg/dL, or a permissive threshold group, targeting levels between 65-140 mg/dL. The study will assess maternal and neonatal outcomes to determine the most effective approach for managing GDM. By addressing the lack of consensus on treatment thresholds, this research seeks to provide clearer guidelines for clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Live, non-anomalous fetus
* Literacy in English, Spanish, Mandarin, or Arabic
* Patients are also required to provide consent, demonstrate an understanding of the purpose of the study, and agree to the study protocol.

Exclusion Criteria:

* \<18 years at EDD
* pre-existing diabetes or diagnosis of GDM prior to 24 weeks
* multi-fetal gestation
* known major fetal anomaly
* known allergy to insulin
* chronic maternal corticosteroid use
* diagnosis of GDM based on finger sticks alone
* patients who have contraindication to oral glucose tolerance test
* a primary language other than English, Spanish, Mandarin, or Arabic

Where it's running

• Thomas Jefferson University
  Philadelphia, Pennsylvania, United States Recruiting
• University of Rochester Medical Center
  Rochester, New York, United States Not yet recruiting

Study contacts

• Study coordinator: Kavisha Khanuja, MD
• Email: kxk334@jefferson.edu
• Phone: 2159555000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Understanding Gestational Diabetes in Asian Pregnant Women

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• Comparing strict and permissive thresholds for treating gestational diabetes

  This study tests whether starting treatment for gestational diabetes with stricter or more relaxed rules leads to better health outcomes for moms and their babies.

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• Early Glucose Patterns in Pregnant Women at Risk for GDM

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• Lower-extremity blood pressure monitoring during cesarean under spinal anesthesia

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.