Understanding Gestational Diabetes in Asian Pregnant Women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on gestational diabetes mellitus (GDM), a condition that affects pregnant women and can lead to serious health issues for both mothers and babies. It aims to identify different phenotypes of GDM among Asian women by analyzing their cardio-metabolic profiles and treatment responses during pregnancy. Utilizing advanced technologies like continuous glucose monitoring and metabolite profiling, the study seeks to provide insights that could lead to more personalized treatment strategies for managing GDM. By understanding the heterogeneity of GDM, the researchers hope to improve clinical outcomes for affected mothers and their children.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Gestational age of ≤ 13 weeks 6 days
* Overweight and obese subjects with BMI of 23kg/m² - 24.9kg/m² and ≥ 25.0kg/m², respectively
* Aged 21-45 years with singleton pregnancy
* Plan to be followed up during the whole pregnancy and deliver at NUH
* Chinese, Malay or Indian ethnicity for pregnant subject
* Can complete questionnaires in English language
* Willing to wear continuous glucose monitoring device at least for 7 days at each required clinic visit

Exclusion Criteria:

* Participants who are not Singapore citizens or Singapore Permanent Residents, not intending to eventually deliver in Singapore National University Hospital and to reside in Singapore for the next 2 years
* Have serious skin conditions (eg. eczema) that precludes wearing the sensor for 14 days
* With history of Type 1 diabetes or Type 2 diabetes
* With chronic preexisting life-threatening conditions including pancreatic cancer, end-stage kidney dysfunction, and psychosis
* Unable to read or speak English

Where it's running

• Department of Obstetrics & Gynaecology
  Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Ling-Jun Li, MD, PhD
• Email: obgllj@nus.edu.sg
• Phone: 81000229

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.