Investigating early life environmental impacts on health in Shenzhen
Official title: Shenzhen Birth Cohort Study
Run by Sun Yat-sen University · NCT03830879 · Data updated 2026-11-12
This study is trying to see how the environment during pregnancy affects the health of mothers and their children in Shenzhen, China, over seven years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 15 Years to 49 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Sun Yat-sen University Academic / other |
| Locations | 1 site (Shenzhen, Guangdong) |
| Status | Recruiting |
| Started | March 6, 2018 |
| Main results expected | March 5, 2025 |
| Study ends | December 31, 2032 |
| Registry record updated | February 5, 2019 |
| Trial ID | NCT03830879 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pregnant women planning to deliver and participate in child care at the hospital in Shenzhen, who are less than 20 weeks pregnant.
✕Probably not a fit
Patients who are more than 20 weeks pregnant or unable to deliver at the participating hospital will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Shenzhen Birth Cohort Study aims to explore how early life environmental exposures affect both short- and long-term health outcomes. This observational study will recruit 10,000 pregnant women in Shenzhen, China, and follow them for seven years, collecting biological samples, questionnaires, and data on child growth and development. The research is supported by local health authorities and involves a multidisciplinary team of public health experts. The study seeks to provide evidence for the Developmental Origins of Health and Disease (DOHaD) hypothesis and identify prevention strategies for childhood diseases.
Why it matters
Potential benefit: If successful, this study could lead to improved health outcomes for children by identifying risk factors associated with pregnancy complications and childhood diseases.
How similar studies have gone: Other studies have shown success in similar observational approaches, particularly in understanding the impact of early life exposures on health outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Pregnant women plan to delivery and participate in child care in our hospital; 2. Pregnant women plan to reside in Shenzhen for at least 7 years; 3. Pregnant women who show interest in the study and agree to provide informed consent; 4. Gestational weeks are less than 20 weeks.Those who will agree that their neonatal will be included in the study and be followed up regularly in our child health clinic until an age of 7 years. Exclusion Criteria: * Pregnant women who have been pregnant for more than 20 weeks; refuse to participate; unable to guarantee delivery in our hospital or can't participate in child care in our hospital; mentally incapacitated and need guardians; or be unwilling to sign informed consent.
Where it's running
-
RuiGao
Shenzhen, Guangdong, China Recruiting
Study contacts
- Study coordinator: Li Cai
- Email: caili5@mail.sysu.edu.cn
- Phone: 0086 20 87334956
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Exploring the impact of maternal microbiota on child health
This study looks at how the bacteria in pregnant women's bodies affect their babies' health and development to see if it can help prevent future health issues.
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This project will try to see if insulin resistance and how the body burns fats early in pregnancy predict later preeclampsia or gestational diabetes in people at higher risk.
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-
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This project will test whether providing pregnant people with healthy food and grocery funds during pregnancy reduces excessive weight gain compared with enhanced usual care.
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Examining how aspirin metabolism relates to metabolic dysfunction in pregnant individuals at risk of preeclampsia
This study is trying to see how the way pregnant people process aspirin relates to their metabolic health and the health of their babies, especially for those at risk of preeclampsia.
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Comparing early and late blood glucose monitoring in pregnant women with a history of gestational diabetes
This study tests if pregnant women with a history of gestational diabetes do better when they monitor their blood sugar early in pregnancy instead of waiting until later.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.