Condition
Gestational Hypertension clinical trials and research
As of November 12, 2026, Find a Trial lists 21 Gestational Hypertension clinical trials that are recruiting, at sites in 9 countries (most in United States (13), Croatia (1), Belgium (1)). By phase: Phase 4 (5), Phase 2 (1), Phase 3 (1). The most active sponsors are University of Alabama at Birmingham (2), Ohio State University (2). There are also 2 NIH-funded research projects on Gestational Hypertension, with $3.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 21Clinical trials
- 2NIH research projects
- 9Countries
Newest Gestational Hypertension clinical trials
All recruiting trials (21)
-
MH-Rx: Check-in on You, Your Medication, and Your Blood Pressure for Pregnant People
This trial tests whether adding virtual social-support and medication management to remote blood pressure monitoring helps pregnant people with chronic or gestational hypertension.
-
Community health worker support to lower blood pressure after pregnancy with high blood pressure
Postpartum patients with high blood pressure after pregnancy will try a program where a trained community health worker helps them monitor blood pressure and manage care for 6 months to see if it lowers blood pressure compared with usual care.
-
Endothelial Biomarkers in Pregnancy: Endothelial Extracellular Vesicles and Hypertensive Disorders
This study tests whether endothelial extracellular vesicles in the blood differ between normotensive pregnant women and those with hypertensive disorders of pregnancy.
-
Aspirin with or without low‑molecular‑weight heparin to prevent preeclampsia in high‑risk pregnancy
This trial tests whether adding low‑molecular‑weight heparin (tinzaparin) to low‑dose aspirin reduces the chance of preeclampsia in pregnant people identified as high risk in the first trimester.
-
Blood markers (sFlt-1/PlGF, sEng, OPG) for diagnosing and monitoring preeclampsia
This study will test whether three blood markers—the sFlt-1/PlGF ratio, soluble endoglin (sEng), and osteoprotegerin (OPG)—can help diagnose and track preeclampsia in pregnant women between 20 and 36 weeks of gestation.
-
Postpartum high blood pressure: trying enalapril after delivery
This study tests whether giving enalapril after delivery can help postpartum women with hypertensive disorders of pregnancy manage blood pressure.
-
Spironolactone to improve blood pressure after pregnancy-related hypertension
This trial will try taking spironolactone for three months after delivery to see if it lowers blood pressure and prevents heart changes in women who had preeclampsia or gestational hypertension and were overweight before pregnancy.
-
Vagus nerve stimulation for mild preeclampsia
This trial will try vagus‑nerve stimulation physiotherapy (trigger point release and positional release) to help control blood pressure and inflammation in pregnant women with mild preeclampsia.
-
Remote monitoring and education for postpartum blood pressure management
This study is testing if a program that combines remote blood pressure monitoring and education with daily text reminders can help new moms manage high blood pressure after giving birth.
-
Moms@Home: a storytelling mobile app to help manage blood pressure in pregnancy
This pilot will test whether the Moms@Home mobile app plus a home blood pressure monitor helps pregnant people with gestational or chronic high blood pressure monitor and manage their blood pressure.
-
Delivering HOPE: healthy food and grocery support during pregnancy
This project will test whether providing pregnant people with healthy food and grocery funds during pregnancy reduces excessive weight gain compared with enhanced usual care.
-
Using dapagliflozin to reduce cardiovascular risk after hypertensive pregnancies
This study is testing if the medication dapagliflozin can help reduce heart risks for women who had high blood pressure during pregnancy after they give birth.
-
Using digital health tools to improve care for pregnant refugee women with high blood pressure
This study is testing if using smartwatches and blood pressure cuffs can help pregnant refugee women with high blood pressure get better care and catch health issues earlier.
-
Atorvastatin after pregnancy to lower future heart disease risk
This study will test whether taking atorvastatin for three months after stopping breastfeeding lowers future cardiovascular risk in people who had high blood pressure during pregnancy.
-
Comparing two doses of aspirin to prevent pregnancy-related high blood pressure issues
This study is testing if a higher dose of aspirin can better prevent high blood pressure problems during pregnancy for women at risk.
-
Using low-dose aspirin after preeclampsia to improve recovery
This study is testing if taking low-dose aspirin for six months after having preeclampsia can help new moms recover better by improving their blood pressure and blood vessel function.
-
Peking University Weifang Birth Cohort
This project will follow pregnant women in Weifang and their children to see if pre-pregnancy and prenatal exposures affect maternal and child health up to age 18.
-
Using angiogenic factors to manage gestational hypertension
This study tests if certain biological markers can help doctors decide the best time to deliver babies for pregnant women with gestational hypertension to keep both mom and baby safe.
-
Exercise and Heart Health in Women at Risk for Pregnancy Complications
This study is testing whether different types of exercise can improve heart health in women at risk for pregnancy complications before they conceive.
-
Lowering blood pressure in pregnant women with hypertensive disorders to prolong pregnancy
This study is testing if lowering blood pressure in pregnant women with high blood pressure can help them stay pregnant longer and improve outcomes for both mom and baby.
-
Predicting progression from gestational hypertension to preeclampsia in pregnant women
This study is trying to find out if certain blood vessel markers can help predict if pregnant women with gestational hypertension will develop preeclampsia.
NIH-funded research (2)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Dynamic risk prediction and subtyping of hypertensive disorders in pregnancy
A digital health approach uses AI to spot early warning signs of preeclampsia and gestational hypertension from pregnancy data, so clinicians can tailor care for pregnant people.
-
Gestational hypertension and preeclampsia: better blood pressure targets before delivery
This study tests whether keeping blood pressure under 140/90 mmHg (instead of 160/110) during pregnancy with high blood pressure improves outcomes for mothers and babies.
Related topics
Quick answers
How many Gestational Hypertension clinical trials are recruiting right now?
21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 9 countries. The most sites are in United States (13 trials), Croatia (1 trial), Belgium (1 trial), China (1 trial), Panama (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 5, Phase 2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.