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Clinical trials and research at University Hospital, Clermont-Ferrand
As of November 12, 2026, Find a Trial lists 104 clinical trials run by University Hospital, Clermont-Ferrand that are recruiting, in France. 1 was first registered in the last 30 days. By phase: Phase 3 (4), Phase 2 (4), Phase 4 (3). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 104Clinical trials
- 1New in 30 days
- 1Country
Newest trials
All recruiting trials (104)
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Ovarian drilling via vNOTES laparoscopy for PCOS patients
This study tests whether drilling the ovaries using vNOTES laparoscopy can help women with PCOS who did not respond to first-line medicines.
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Work and leisure physical activity short questionnaire validation
This study tests a shorter questionnaire to see if it accurately measures work and leisure activity and sedentary time by comparing it with a well-established reference questionnaire.
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AI-assisted embryo selection on day 5 in IVF for infertility
This trial tests whether an AI-based embryo selection tool can help pick the best embryo for transfer on day 5 in IVF/ICSI to improve pregnancy chances for people with infertility.
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Endothelial Function in Healthy Women Over 50 See How Your Blood Vessels Work
This study tests whether flow-mediated dilation (FMD) measurements in healthy women aged 50 and older can establish reference values.
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Preventive habits of physicians (PREVMED) so doctors’ cancer screening and lifestyle advice patterns
This study tests how doctors and medical residents practice prevention with patients, and what personal or work factors might influence those practices.
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Impact of Phosphate Supplementation on FGF23 Levels in Hypophosphatemia Patients
This study tests whether giving phosphate affects FGF23 levels in adults with low phosphate who need supplementation.
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Brief Suicidal Crisis Prevalence in Psychiatric Settings
This observational study tests how common a brief suicidal crisis (under 24 hours) is among adults seen by psychiatrists in Clermont-Ferrand, France.
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Compare how much pain kids feel during local anesthesia with what a parent thinks they feel
This study tests whether a parent can accurately gauge their child’s pain during local anesthesia during dental treatment.
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Nurse-led discharge education for heart failure patients
This project tests whether a nurse-run discharge education program helps adults with heart failure avoid unplanned readmissions within 30 days after leaving the hospital.
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Plant-based Diet in Older Adults: How It Affects Muscle Health
This study tests whether increasing plant-based foods in the diet of healthy adults 65 and older changes muscle strength and health compared with a diet with more animal foods.
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Masticatory Performance in Adults with Periodontitis
This study tests whether chewing performance correlates with how severe periodontitis is in adults who have the condition.
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See if periodontal treatment improves chewing ability and oral quality of life
This study tests whether treating periodontitis improves how well people can chew and how they feel about their oral health.
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Impact of maternal physical activity on birth biology and cord blood markers
This study looks at whether a mother's physical activity during pregnancy affects biological markers in the newborn, using cord blood samples.
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Treatments for sore throat linked to acute pharyngitis and viral tonsillitis
This post-marketing follow-up checks four products (HMG, PHN, PHR, TUR) in people with sore throats from acute pharyngitis or viral tonsillitis to see if they are safe and helpful in real-world use.
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Markers to Predict Sudden Cardiac Death Risk After MI with Moderate LVEF
This study tests a risk-score approach to see if certain MRI findings, biomarkers, and other tests can predict sudden cardiac death in people who survived a heart attack and have moderately reduced heart function.
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How well maxillofacial prosthetics help chewing and daily life after upper throat cancer
This study tests whether maxillofacial prosthetic rehabilitation improves chewing, orofacial function, and quality of life in adults who have been treated for cancer of the upper aerodigestive tract.
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Does distending the intestine change how we see Crohn's activity on MRI?
This study tests whether adding an intestinal distensionagent before MRI changes the measurement of Crohn's inflammation in adults with ileal or colonic disease.
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Measuring bile acids in blood and tumor tissue to help detect and predict treatment response in testicular germ cell tumors
This project will measure bile acids and related signals in blood and tumor tissue to see if they can help detect disease and predict chemotherapy response in adult men with testicular germ cell tumors.
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Blood microRNA markers for chemotherapy-related peripheral nerve damage in lung and colorectal cancer
This study will test whether levels of tiny blood molecules called microRNAs can predict how often and how badly patients with lung or colorectal cancer get nerve damage from certain chemotherapies.
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miR-1 as a blood biomarker for muscular dystrophies and congenital myopathies
This project will see if levels of a blood molecule called miR-1 can track disease status in people with Duchenne/Becker muscular dystrophy, myotonic dystrophy type 1, congenital myopathies, and in healthy volunteers.
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Post-marketing follow-up of four devices for acute viral rhinitis and related conditions
This study tests four medical devices (NS, NHE, NHG, and PIR) in real-life use to see if they are safe, tolerated, and helpful for people with acute viral rhinitis, rhinosinusitis, or rhinopharyngitis.
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Understanding barriers to changing risky eating in families of kids with severe early childhood caries
This study tests how families respond to guidance to change sugary eating habits for children under six with severe early childhood caries.
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Ketoanalogue supplements to protect muscle in advanced chronic kidney disease on a moderately low‑protein diet
This tests whether adding ketoacid/amino‑acid supplements to a moderately low‑protein diet helps protect muscle and slow kidney decline in adults with stage 4–5 chronic kidney disease who are not yet on dialysis.
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Optical genome mapping to find genetic causes of multiple congenital anomalies with or without intellectual disability
This project will try optical genome mapping to detect structural genetic changes in people with multiple congenital anomalies (with or without intellectual disability) when prior whole-genome sequencing did not give an answer.
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Sphenopalatine ganglion block versus epidural blood patch for post-dural puncture headache
This test compares a sphenopalatine ganglion block and an epidural blood patch to see which relieves post-dural puncture headaches better in adults whose pain hasn't improved after 24 hours of usual treatment.
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How GFAP and UCH-L1 Blood Tests Could Help Personalize Care for Older Recurrent Fallers
This study tests whether a bedside blood test for GFAP and UCH-L1 can help identify intracranial bleeding in older adults who have fallen and are in the hospital, potentially reducing the need for CT scans.
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Two CE‑marked throat sprays for adults with a recent dry or productive cough
This study will try two CE‑marked throat sprays to see if adults with a recent viral cough tolerate them well and get symptom relief.
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Best way to fix under‑expanded coronary stents in resistant blockages
This compares intravascular lithotripsy (IVL) with high‑pressure or specialty balloons to see if IVL opens under‑expanded coronary stents better in people with in‑stent restenosis.
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From Commensal to Pathogenic Enterococcus: Understanding How Enterococcus faecalis Causes Endocarditis
This study tests how Enterococcus faecalis from the gut can lead to infective endocarditis in adults who have a positive blood culture and are on antibiotics, to better understand why it becomes dangerous.
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Heart failure telemonitoring eligibility after program exclusion
This study tests whether patients who stop telemonitoring due to criteria no longer being met have a low risk of worse health outcomes.
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How a mother's physical activity during pregnancy affects a newborn's heart patterns and oxygen levels
This project will see if how much a pregnant woman exercises changes her baby’s heart rate patterns and oxygen levels after birth.
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Sexuality and mental health in people aged 60 and over
This project will see if aspects of sexuality are linked with mental health in people aged 60 and over who live in the community.
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Anesthesia choice for mechanical thrombectomy in ischemic stroke
In people with severe ischemic stroke due to a large vessel blockage who need mechanical thrombectomy, this study tests whether general anesthesia works better than procedural sedation for improving daily function 3 months later.
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PET-MRI to study the reward system in Parkinson's disease with RBD
This study uses PET‑MRI to see how dopamine-related reward pathways behave in people with Parkinson’s who also have REM sleep behavior disorder.
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Tislelizumab for people 70+ with advanced esophageal squamous-cell cancer who are unfit for chemotherapy
This trial will try the anti–PD-1 drug tislelizumab, given by IV every 3 weeks, as first-line treatment for people aged 70 and older with advanced esophageal squamous-cell carcinoma who cannot receive platinum chemotherapy to see how many are alive at 6 months.
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How exercise affects FGF21 and follistatin in people with cirrhosis and liver cancer
This study tests whether submaximal cycling changes levels of hepatokines FGF21 and follistatin in patients with hepatocellular carcinoma on cirrhosis.
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Veno-arterial CO2 gap-guided early resuscitation for septic shock
This trial tests whether using the veno-arterial CO2 gap instead of lactate to guide early resuscitation helps adults with septic shock survive.
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Does tryptophan affect how well triptans relieve migraine?
This test sees if tryptophan levels and their by-products influence how well triptans relieve migraine attacks in adults who have been identified as triptan responders or non-responders.
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Detecting cancer cells in frozen ovarian or testicular tissue from children with neuroblastoma or Ewing sarcoma
This project will test whether RT-qPCR or droplet digital PCR (ddPCR) better detects leftover neuroblastoma or Ewing sarcoma cells in frozen ovarian or testicular tissue from children treated during infancy.
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Suppressive Functions of Regulatory T Cells in Migraine
This study tests whether regulatory T cells can help control migraine-related inflammation in adults with chronic migraine.
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Resting-state brain imaging in postmenopausal osteoporosis
This project will use resting-state MRI scans, questionnaires, bone density testing, and blood tests to see if brain connectivity and bone-remodeling markers differ between postmenopausal women with osteoporosis (with and without fractures) and matched healthy postmenopausal volunteers.
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Intestinal microsporidiosis in French heart transplant recipients
This project will collect past medical data to see how often and how severe intestinal microsporidiosis is in heart transplant patients in France.
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Using early fecal calprotectin to prevent Crohn's disease return after intestinal surgery
This trial tests whether measuring fecal calprotectin early after bowel surgery and intensifying ustekinumab when levels rise can prevent Crohn's disease from coming back in adults at higher risk.
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Using music to reduce stress during botulinum toxin injections for spasticity
This study tests if listening to music during botulinum toxin injections can help adults with spasticity feel less pain and anxiety.
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Using sublingual sufentanil for managing moderate to severe pain in emergencies.
This study is testing if a new way of giving sufentanil under the tongue can help adults with moderate to severe pain from injuries feel better faster in emergency situations compared to regular pain management methods.
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How dentists' communication affects para-apical anesthesia experiences
This trial will test whether hypnotic-style communication versus conventional warnings changes pain and anxiety for adults receiving para-apical dental anesthesia.
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Passive versus passive-plus-active hamstring stretching for flexibility in chronic low back pain
This study will see if adding active hamstring stretches to passive stretches improves flexibility for adults with chronic low back pain.
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Preventing bleeding during myomectomy with misoprostol
This will test whether giving misoprostol before myomectomy reduces surgical bleeding in women aged 18–43 having surgery for symptomatic uterine fibroids.
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Carvedilol effect on portal pressure measured by endoscopic ultrasound
We will test whether one month of carvedilol (titrated to 12.5 mg daily) lowers portal pressure to help prevent digestive bleeding in adults with cirrhosis.
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Characterizing De Santo Shinawi Syndrome in patients with WAC gene variants
This study is trying to learn more about De Santo Shinawi Syndrome by collecting information from people with changes in the WAC gene to help improve diagnosis and care for those affected.
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Using AI to predict necrotizing enterocolitis in premature babies through stool analysis
This study is trying to see if using AI to analyze stool samples from premature babies can help predict who is at risk for necrotizing enterocolitis, so doctors can take steps to prevent it.
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Using virtual reality to reduce pain and anxiety during needle placements in children with leukemia
This study tests if using virtual reality can help reduce pain and anxiety for kids with leukemia during needle placements.
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Comparing two types of polyethylene in knee replacement surgery
This study is testing which type of plastic used in knee replacement surgery helps patients feel better and move more easily after their operation.
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Investigating Vitamin B12 Levels in Patients on Tocilizumab
This study is trying to see if vitamin B12 levels change in patients with autoimmune diseases who are being treated with tocilizumab during flare-ups compared to when they're feeling better.
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Evaluating the effects of oxaliplatin on liver and nerve toxicity in cancer patients
This study is testing how the cancer drug oxaliplatin affects the liver and nerves in patients with pancreatic and esophageal cancers to help make chemotherapy safer and more effective.
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Early detection of fistulas after total laryngectomy using cytokine measurement
This study is testing if measuring certain proteins in drainage fluids after throat surgery can help doctors spot problems early and let patients start eating again sooner.
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Improving physical activity and reducing sedentary behavior in pregnant women
This study is testing different ways to help pregnant women be more active and less sedentary to see which method works best for their health and their baby's development.
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Examining blood clotting in pregnant women and the effects of low molecular weight heparin
This study looks at how blood clotting changes during and after pregnancy to see if a blood thinner called low molecular weight heparin works better for pregnant women at risk of blood clots.
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Using osteopathic techniques to improve quality of life after endometriosis surgery
This study is testing if osteopathic techniques can help women feel better and improve their quality of life after surgery for endometriosis by reducing painful complications.
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Using a health app to promote physical activity in people with chronic low back pain
This study is testing how a health app can help people with chronic low back pain stay active by understanding what motivates them and what challenges they face.
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Who is at risk for neuropathic pain during cancer care.
We will try to use repeated cognitive-emotional and pain assessments to see who among adults with breast, gynecologic, colorectal, or lung cancer is likely to develop neuropathic pain during or after treatment.
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Using hypnosis to reduce pain during stitches in the emergency room
This study is testing whether using hypnosis can help reduce pain and stress for people getting stitches in the emergency room.
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Daily adapted physical activity to improve sleep in children 5–16 with blood cancer
This trial will see if doing adapted physical activity every day instead of only once over four days improves sleep for children aged 5–16 who are receiving treatment for blood cancers.
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Using capsaicin patches to treat painful hand osteoarthritis
This study is testing if a stronger capsaicin patch can help people with painful hand osteoarthritis feel less pain compared to a weaker version.
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Immune signals and regulatory T cells in migraine
This research will test whether blood immune markers and regulatory T cells are linked to migraine in women ages 18–50 who have migraine or certain autoimmune/inflammatory conditions.
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Using the Quadriceps Combined Test to Diagnose and Monitor ALS
This study is testing a new way to diagnose and track ALS using a special test to see how well the muscles and nerves are working in people who might have the disease.
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Predicting premature births using vaginal microbiota analysis
This study is testing if analyzing the bacteria in the vagina can help predict premature births in pregnant women who are at risk.
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Monitoring hand, foot and mouth disease in children
This study is trying to find out which types of viruses cause hand, foot, and mouth disease in kids by collecting samples from children with symptoms to help track outbreaks.
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Improving egg freezing techniques for fertility treatments
This study is testing a new way to freeze donor eggs to see if it helps them survive better and leads to more successful pregnancies when used in fertility treatments.
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Understanding migraines and neuropathic pain in osteoarthritis patients
This study looks at how often people with osteoarthritis experience migraines and nerve pain to better understand the connection between these conditions.
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Assessing stress levels in medical students during exams
This study tests how stressed medical students feel during different types of exams by measuring their heart rate changes.
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Assertiveness and emotion-management difficulties in adults with Tourette syndrome
This will test how common assertiveness difficulties are in adults with Tourette syndrome by asking them to complete online questionnaires.
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Assessing biological age and frailty in newly diagnosed chronic leukemia patients for personalized treatment
This study is testing how to personalize treatment for newly diagnosed chronic myeloid leukemia patients by looking at their biological age and overall health.
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Evaluating a decision aid for shared decision making in healthcare
This study tests a new tool to help patients and doctors work together better when deciding about optional prescription drugs to see if it reduces confusion and improves comfort with their choices.
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Real-life data collection for patients with Chronic Myeloid Leukemia
This study is collecting information from people with Chronic Myeloid Leukemia to see how different treatments work and how they affect patients over time.
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Impact of workplace sedentary behavior interventions on health in emergency responders
This study is testing if using sit-and-stand desks or exercise bikes can help emergency responders like dispatchers and firefighters reduce sitting time and improve their health.
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Measuring workplace satisfaction and well-being using visual analog scales
This study is testing a simpler way to measure how happy and satisfied people feel at work to see if it helps them share their experiences better.
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Effects of testosterone gel on physical performance in critically ill patients
This study tests if giving testosterone gel to critically ill patients on a ventilator can help improve their muscle strength and recovery compared to a placebo.
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Evaluating chewing function in children with oral health issues
This study is testing how chewing ability changes in children with oral health problems during treatment to see how it affects their eating habits and overall growth.
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Helping osteoarthritis patients walk with NSAIDs
This study is testing a new program that combines special exercises and occasional use of pain relief medications to help people with hip or knee osteoarthritis walk better.
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Using a computerized attention test to help manage concussion in young rugby players
We will test if a computerized attention battery can detect attention problems after concussion in 11–25-year-old rugby players by comparing them with similar athletes without concussion.
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Diet workshop for improving protein intake after bariatric surgery
This study tests whether a dietary workshop can help people who had bariatric surgery improve their protein intake for better recovery and health.
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Evaluating Antiplatelet and Anticoagulation Therapy in Hereditary Hemorrhagic Telangiectasia
This study is testing how well people with Hereditary Hemorrhagic Telangiectasia can handle new blood-thinning treatments compared to not using them, to find out which ones work best for them.
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Wearable activity signatures to spot risk of additional chronic conditions
This project tests whether wearable sensors can find activity patterns that predict new chronic conditions in people who already have chronic diseases.
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Detecting risky behaviors in agitated, bedridden neurosurgery patients
This project will try to detect and record risky behaviors in hospitalized bedridden patients who are agitated or confused so clinicians can understand how often and what types occur.
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MRI vs. pathology in bladder tumor staging
This study tests whether MRI can reliably indicate bladder tumor stage before TURB in adults with confirmed bladder tumors.
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Understanding resistance to venetoclax in chronic lymphocytic leukemia
This study is trying to understand why some patients with chronic lymphocytic leukemia don’t respond to the treatment venetoclax by looking at their medical information and samples.
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Impact of Osteoporosis Treatment on Vascular Health and Pain in Postmenopausal Women
This study is testing how osteoporosis treatments affect heart health, pain, and quality of life in postmenopausal women.
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Treatment of oral mucositis caused by chemotherapy and radiation
This study is testing if a new mouth solution called Orosol® can help people with painful mouth sores caused by chemotherapy and radiation feel better and heal faster.
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Moderate CO2 increase during anesthesia to boost collateral flow in clot removal for acute anterior stroke
This study will test whether slightly higher blood carbon dioxide during anesthesia improves collateral blood flow and protects the brain in people having mechanical thrombectomy for anterior large-vessel ischemic stroke.
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Evaluating MRI's role in managing Crohn's disease with biotherapy
This study is testing if adding MRI scans to the treatment plan helps people with Crohn's disease on biotherapy feel better and heal more effectively compared to standard follow-ups.
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Impact of long working hours on stress in ophthalmology physicians and residents
This study tests how long working hours affect stress and heart health in ophthalmology doctors and residents to see if their demanding schedules are taking a toll on them.
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Fecal Microbiota Transplantation to Prevent Complications After Stem Cell Transplantation
This study is testing whether giving a special stool treatment can help prevent complications like Graft-versus-Host Disease in patients receiving stem cell transplants for blood cancers.
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Cohort of patients with chronic pain using an e-health application
This study is trying to see how an e-health app can help track and understand the experiences of people with chronic pain over two years.
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Exploring brain metabolism in early Parkinson's disease using advanced MRI techniques
This study is testing how brain chemistry changes in people who have just been diagnosed with Parkinson's disease compared to healthy individuals using advanced MRI technology.
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Effects of anticoagulant interruption and left atrial occlusion in patients with bleeding from radiation cystitis and atrial fibrillation
This study looks at patients who have bleeding from radiation cystitis while on blood thinners for atrial fibrillation to see how these factors affect their treatment and outcomes.
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Mapping neurosensory disorders and pain in patients treated for oral cavity and oropharynx cancer
This study is trying to understand and track nerve-related issues and pain in patients who have been treated for cancers in the mouth and throat.
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Evaluating mobility issues in patients with chronic illnesses
This study is trying to understand how mobility issues affect people with chronic illnesses over five years to help create a better way to identify and care for those who struggle with movement.
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Optimizing a non-invasive method to study auditory nerve function
This study is testing a new way to measure how well the auditory nerve works in healthy people to help find hidden hearing loss that regular tests might miss.
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Assessing readiness for extubation in brain-injured patients
This study is testing a new way to see if brain-injured patients are ready to be taken off a breathing machine to help them recover better and avoid complications.
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Effects of different screen sizes on stress measurement
This study tests how different screen sizes affect people's stress levels as measured by a simple scale and looks at how these responses change over a week.
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Assessing health and exercise responses in children with chronic diseases
This study is testing how chronic diseases and their treatments affect physical fitness in children and teens to find ways to improve their health and quality of life through exercise.
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Maintaining aspirin use during kidney stone lithotripsy
This study is testing if continuing aspirin use during kidney stone treatment helps patients feel better and have fewer complications.
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Using a special solution to prevent infections in dialysis catheters
This study is testing a new solution made of ethanol and heparin to see if it can help prevent infections in dialysis catheters for people on chronic hemodialysis.
Quick answers
How many clinical trials run by University Hospital, Clermont-Ferrand are recruiting right now?
104, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in France. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 4, Phase 2: 4, Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.