Wearable activity signatures to spot risk of additional chronic conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The eMOB study will follow 700 patients with a range of chronic diseases at CHU Clermont-Ferrand for four years, collecting annual clinical measures and continuous movement data from accelerometers and wearable sensors. Researchers will combine quantitative movement metrics with detailed sequence analysis and tailor algorithms to each disease and context to derive a personalized digital signature of physical activity and sedentary behavior. They will then examine whether that signature is associated with the later appearance of one or more additional comorbidities during follow-up. The approach aims to detect risk patterns before clinical complications arise so that earlier interventions might be possible.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient follow-up at CHU Clermont-Ferrand for a chronic disease in one of the following observational cohorts:

  * Inflammatory rheumatic disease(rheumatoid arthritis, spondyloarthritis) included in the RCVRIC cohort (CPP Sud-Est VI N° ID-RCB- A01847-40)
  * Pre-surgical knee and hip osteoarthritis (Evalmob) (ID-RCB N° 2019- A01017-50)
  * Major depressive disorder included in the FACE-DR cohort (CNIL agreement: DR- 2015-673) and Bipolar disorder included in the FACE-BD cohort (CPP Ile de France IX; January 18, 2010) of the Adult Psychiatry Department B
  * Type 2 diabetes included in the cohort of the sport medicine service "Rehabilitation T2" (CNIL agreement 0164)
  * Obesity included in the "Obesity" sports medicine service cohort (CNIL agreement 0164)
  * COPD included in the "COPD Rehabilitation" sports medicine service cohort (CNIL agreement 0164)
  * Chronic pain cohort (eDOL) (CPP West II N° ID-RCB 2020-A02027-32)
* Affiliation to a social security system.
* Able to provide written informed consent to participate in the research.

Exclusion Criteria:

* Inability to practice physical activity
* Pregnant or breastfeeding
* Refusal to participate
* Minors or adults under the protection of the law or under the protection of justice.

Where it's running

• CHU de Clermont-Ferrand
  Clermont-Ferrand, France Recruiting

Study contacts

• Principal investigator: Anne Tournadre — University Hospital, Clermont-Ferrand
• Study coordinator: Lise LACLAUTRE
• Email: promo_interne_drci@chu-clermontferrand.fr
• Phone: +33473754963

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.