Monitoring hand, foot and mouth disease in children

Prospective Clinico-virological Surveillance of Diseases Foot-hand-mouth/Herpangina Associated With Enteroviruses in Pediatric Outpatients

Observational University Hospital, Clermont-Ferrand · NCT06263439

This study is trying to find out which types of viruses cause hand, foot, and mouth disease in kids by collecting samples from children with symptoms to help track outbreaks.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
AgesN/A to 10 Years
SexAll
SponsorUniversity Hospital, Clermont-Ferrand Academic / other
Locations1 site (Clermont-Ferrand)
Trial IDNCT06263439 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify the types of enteroviruses responsible for hand, foot and mouth disease (HFMD) and herpangina in pediatric outpatients. Children aged 0 to 10 years presenting with symptoms suggestive of these conditions will have throat or mouth swabs collected by pediatricians. The samples will be sent to a national reference laboratory for enterovirus detection and genotyping, while demographic and clinical data will also be gathered during the consultation. The study seeks to detect potential epidemics and compare the characteristics of different enterovirus types.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 0 to 10 years who show signs of hand, foot and mouth disease or herpangina.

Not a fit: Patients who refuse to participate or are older than 10 years may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance early detection and management of enterovirus infections in children.

How similar studies have performed: Other studies have successfully monitored enterovirus infections, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children aged 0 to 10 years presenting with HFMD or herpangina

Exclusion Criteria:

* Refusal to participate by holders of parental authority
* Refusal to participate for children over 3 years of age

Where this trial is running

Clermont-Ferrand

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hand, Foot and Mouth DiseaseHerpanginaEnterovirus InfectionsHand, foot and mouth diseaseEnterovirus A71Coxsackievirus A6Primary care in paediatrics
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.