Assessing health and exercise responses in children with chronic diseases
Evaluation of Chronic Pathologies Impact and Their Treatments on Children and Teen Physical Fitness.
This study is testing how chronic diseases and their treatments affect physical fitness in children and teens to find ways to improve their health and quality of life through exercise.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 6 Years to 18 Years |
| Sex | All |
| Sponsor | University Hospital, Clermont-Ferrand Academic / other |
| Locations | 1 site (Clermont-Ferrand) |
| Trial ID | NCT03913962 on ClinicalTrials.gov |
What this trial studies
This project aims to evaluate the effects of chronic pediatric diseases and their treatments on physical fitness in children and adolescents. Participants will be grouped based on disease activity and treatment status to assess how these factors influence physical fitness. The study will involve physical tests to measure body composition, muscle strength, and metabolic flexibility, alongside blood tests to evaluate inflammatory states. The goal is to improve treatment strategies through physical activity, reducing pain and enhancing quality of life.
Who should consider this trial
Good fit: Ideal candidates are children aged 6 to 18 with chronic pathologies that affect muscle mass and function.
Not a fit: Patients currently on systemic corticosteroids or with contraindications to physical activity may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment approaches that enhance physical fitness and quality of life for children with chronic diseases.
How similar studies have performed: Other studies have shown promise in using physical activity as a therapeutic approach for chronic pediatric conditions, indicating potential success for this innovative methodology.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * for patients: * Aged between 6 and 18-year-old * Male or female * Presenting a chronic pathology / having a treatment which is known to alter muscle mass and function, metabolism and body composition * Included in the active list of the hospital centre of Clermont-Ferrand * Free and informed consent of the holders of parental authority and the patient * Affiliated with the social security system for control: * Aged between 6 and 18-year-old * Male or female * Free and informed consent of the holders of parental authority and the patient * Affiliated with the social security system Exclusion Criteria: * for patients: * Treatment by systemic corticoids (\>1 week in the 30 days before test) * Contraindication to sport practice * Active infection for control: * Contraindication to sport practice * Chronic pathology susceptible to alter muscle mass and function, metabolism and body composition * Treatment susceptible to alter metabolism * Active infection
Where this trial is running
Clermont-Ferrand
- Chu Clermont-Ferrand — Clermont-Ferrand, France (Recruiting)
Study contacts
- Principal investigator: Etienne MERLIN — University Hospital, Clermont-Ferrand
- Study coordinator: Lise LACLAUTRE
- Email: drci@chu-clermontferrand.fr
- Phone: 04 73 75 49 63
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.