Assessing health and exercise responses in children with chronic diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to evaluate the effects of chronic pediatric diseases and their treatments on physical fitness in children and adolescents. Participants will be grouped based on disease activity and treatment status to assess how these factors influence physical fitness. The study will involve physical tests to measure body composition, muscle strength, and metabolic flexibility, alongside blood tests to evaluate inflammatory states. The goal is to improve treatment strategies through physical activity, reducing pain and enhancing quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* for patients:
* Aged between 6 and 18-year-old
* Male or female
* Presenting a chronic pathology / having a treatment which is known to alter muscle mass and function, metabolism and body composition
* Included in the active list of the hospital centre of Clermont-Ferrand
* Free and informed consent of the holders of parental authority and the patient
* Affiliated with the social security system for control:
* Aged between 6 and 18-year-old
* Male or female
* Free and informed consent of the holders of parental authority and the patient
* Affiliated with the social security system

Exclusion Criteria:

* for patients:
* Treatment by systemic corticoids (\>1 week in the 30 days before test)
* Contraindication to sport practice
* Active infection for control:
* Contraindication to sport practice
* Chronic pathology susceptible to alter muscle mass and function, metabolism and body composition
* Treatment susceptible to alter metabolism
* Active infection

Where it's running

• Chu Clermont-Ferrand
  Clermont-Ferrand, France Recruiting

Study contacts

• Principal investigator: Etienne MERLIN — University Hospital, Clermont-Ferrand
• Study coordinator: Lise LACLAUTRE
• Email: drci@chu-clermontferrand.fr
• Phone: 04 73 75 49 63

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.