Real-life data collection for patients with Chronic Myeloid Leukemia
Official title: Chronic Myeloid Leukemia (CML) Real-Life Database
Run by University Hospital, Clermont-Ferrand · NCT05963061 · Data updated 2026-11-12
This study is collecting information from people with Chronic Myeloid Leukemia to see how different treatments work and how they affect patients over time.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 3500 (estimated) |
| Sponsor | University Hospital, Clermont-Ferrand Academic / other |
| Locations | 14 sites (Annecy and 13 other locations) |
| Status | Recruiting |
| Started | April 16, 2014 |
| Main results expected | April 16, 2034 |
| Study ends | April 16, 2034 |
| Registry record updated | April 9, 2024 |
| Trial ID | NCT05963061 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with Chronic Myeloid Leukemia.
✕Probably not a fit
Patients who have undergone CML allograft without TKI treatment or those unable to provide consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to establish a large cohort of patients diagnosed with Chronic Myeloid Leukemia (CML) to collect long-term follow-up data. It will gather both prospective and retrospective clinico-biological information to facilitate various observational studies, including epidemiological analyses and treatment response evaluations. The study will also assess the impact of evolving treatment recommendations and the use of new therapeutic agents in real-life settings.
Why it matters
Potential benefit: If successful, this study could enhance understanding of CML treatment outcomes and improve patient management strategies.
How similar studies have gone: Other observational studies in hematologic malignancies have shown success in improving treatment strategies and patient outcomes, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient diagnosed for chronic myelocytic leukemia Exclusion Criteria: * CML allograft without TKI treatment * Refusal or inability to sign the consent
Where it's running
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CH Annecy Genevois
Annecy, France Recruiting -
University Hospital, Caen
Caen, France Recruiting -
CHU Clemront-Ferrand
Clermont-Ferrand, France Recruiting -
Centre Hospitalier Emile Roux
Le Puy-en-Velay, France Recruiting -
University Hospital, Limoges
Limoges, France Recruiting -
Institut Paoli-Calmettes
Marseille, France Recruiting
Show 8 more locations
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Centre Hospital, Nancy
Nancy, France Recruiting -
Bicetre Hospital
Paris, France Recruiting -
Hopital Paul Brousse
Paris, France Recruiting -
Rennes University Hospital
Rennes, France Recruiting -
Centre Hospitalier de Rochefort
Rochefort, France Recruiting -
Centre Hospitalier Universitaire de Saint Etienne
Saint-Etienne, France Recruiting -
University Hospital, Toulouse
Toulouse, France Recruiting -
Versailles Hospital
Versailles, France Recruiting
Study contacts
- Study coordinator: Lise Laclautre
- Email: promo_interne_drci@chu-clermontferrand.fr
- Phone: 04 73 75 11 95
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Asciminib for chronic phase CML with T315I mutation
This study tests asciminib 200 mg twice daily in adults with chronic phase CML and a T315I mutation after stem cell transplant to see if it helps control leukemia.
-
Early Tacrolimus Taper After Allogeneic Transplant
This study tests whether stopping tacrolimus early after an allogeneic stem cell transplant is safe and feasible for people with AML, MDS, MF, CML, CMML, or GVHD risk after transplant.
-
Care organization and quality of life for people with chronic myeloid leukemia in the Lombardy hematology network
This project will see if the way hematology centers are organized affects quality of life for adults with chronic myeloid leukemia in Lombardy.
-
Using asciminib to treat chronic myeloid leukemia patients with a specific mutation
This study is testing if a new drug called asciminib can help people with chronic myeloid leukemia who have a specific mutation and haven't had success with other treatments.
-
Second STOP After Pioglitazone Priming in CML Patients
This phase 2 study tests whether adding pioglitazone to a TKI can help CML patients who lost major molecular response after stopping a TKI to regain disease control.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.