Daily adapted physical activity to improve sleep in children 5–16 with blood cancer
Official title: Effect of Practicing Adapted Physical Activity (APA) on Sleep Quality in Children From 5 Years of Age and Adolescents up to 16 Years of Age Undergoing Treatment for a Hematologic Malignancy.
Run by University Hospital, Clermont-Ferrand · NCT06455592 · Data updated 2026-11-12
This trial will see if doing adapted physical activity every day instead of only once over four days improves sleep for children aged 5–16 who are receiving treatment for blood cancers.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 5 Years to 16 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | University Hospital, Clermont-Ferrand Academic / other |
| Locations | 1 site (Clermont-Ferrand) |
| Status | Recruiting |
| Started | November 17, 2025 |
| Main results expected | November 2027 |
| Study ends | November 2027 |
| Registry record updated | December 5, 2025 |
| Trial ID | NCT06455592 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 5–16 who are receiving treatment for hematological (blood) cancer, are enrolled in the Social Security system, and whose parents and they provide informed consent are ideal candidates.
✕Probably not a fit
Children on high‑dose corticosteroids, taking anxiolytics, melatonin or other sleeping pills, with sleep apnea, or with contraindications to adapted physical activity are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center, randomized, open-label crossover trial at CHU de Clermont-Ferrand compares two adapted physical activity schedules to see effects on sleep in children aged 5–16 undergoing treatment for blood cancers. Participants are randomized to a conventional schedule (one adapted physical activity session over four days) or an experimental schedule (daily adapted physical activity for four days), with the study lasting four weeks and including a one-week washout after two weeks. Interventions are delivered at the hospital and continued at home as applicable, with consent obtained from parents and children. Sleep outcomes in the two arms will be compared after statistical analysis to determine the effect of daily adapted physical activity on sleep.
Why it matters
Potential benefit: If successful, daily adapted physical activity could improve sleep quality and overall well-being for children undergoing treatment for blood cancer.
How similar studies have gone: Physical activity has been shown to improve sleep in other pediatric and adult populations, but daily adapted activity during active pediatric cancer treatment has been less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children from 5 to 16 with haematological cancer undergoing treatment * Subjects and their parents who were informed about the study and gave informed consent. * Enrollment in the Social Security system Exclusion Criteria: * Children on high-dose corticosteroids * Children under anxiolytic treatment * Children with sleep disorders (sleep apnea) * Children taking melatonin or sleeping pills * Contraindication to adapted physical activity * Refusal to participate on the part of the participant or his/her parents * Holders of parental authority under curatorship, guardianship, safeguard of justice * Pregnant or breast-feeding teenagers
Where it's running
-
CHU de Clermont-Ferrand
Clermont-Ferrand, France Recruiting
Study contacts
- Principal investigator: Emmanuelle LABRAISE — University Hospital, Clermont-Ferrand
- Study coordinator: Lise Laclautre
- Email: promo_interne_drci@chu-clermontferrand.fr
- Phone: 334.73.754.963
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.