MRI vs. pathology in bladder tumor staging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center interventional study compares MRI findings to anatomopathology results from TURB in patients with newly diagnosed urinary bladder tumors. The goal is to see if MRI can accurately reflect tumor invasion level and potentially reduce reliance on invasive pathology for staging. Eligible participants are adults with bladder tumors confirmed by cystoscopy who are planned for TURB and can read French. MRI is performed with gadolinium contrast unless contraindicated, and results are compared to the gold-standard TURB pathology. The study builds on prior work suggesting MRI improvements may aid bladder cancer staging, aiming to improve diagnostic timing and patient management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient, male or female, aged \>18ans
* Benefiting from Social Security
* Urinary bladder tumour confirmed on cystoscopy and requiring a TURB
* Understanding and reading French well
* Ability to give informed consent

Exclusion Criteria:

* Participation refusal
* MRI contraindication : pacemaker, heart valve, clips, stents, coils, non-MRI compatible defibrillators, neural or peripheral stimulator, cochlear implant, intraocular foreign body, claustrophobia
* Patient under guardianship, deprived of liberty, impaired understanding
* Pregnant/breastfeeding woman
* Allergy to gadolinium (contrast product necessary for carrying out the MRI), hypersensitivity to gadoteric acid or gadolinated contrast products, to meglumine
* Suspicion of an infectious disease such as schistosomiasis (differential diagnosis)
* Patient presenting with macroscopic clotting hematuria on the day of the MRI

Where it's running

• CHU clermont-ferrand
  Clermont-Ferrand, France Recruiting

Study contacts

• Principal investigator: Laurent GUY — University Hospital, Clermont-Ferrand
• Study coordinator: Lise Laclautre
• Email: promo_interne_drci@chu-clermontferrand.fr
• Phone: 334.73.754.963

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.