Sponsor or institution
Clinical trials and research at University College, London
As of November 12, 2026, Find a Trial lists 73 clinical trials run by University College, London that are recruiting, at sites in 24 countries (most in United Kingdom (70), United States (4), Canada (3)). 1 was first registered in the last 30 days. By phase: Phase 3 (10), Phase 1 (9), Phase 2 (7), Phase 1/2 (3). There are also 32 NIH-funded research projects at this institution, with $11.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 73Clinical trials
- 32NIH research projects
- 1New in 30 days
- 24Countries
Newest trials
All recruiting trials (73)
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Monitoring and Early Detection of Treatable Inherited Retinal Disease in Children and Adolescents
This study tests AI tools to spot and track inherited retinal diseases caused by RPE65 and RPGR mutations using widefield eye images in kids and teens.
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Oral Progestin Tablets With Radiotherapy vs. Standard Radiotherapy and Chemotherapy in High-Risk NSMP Endometrial Cancer
This trial tests whether adding oral progestin tablets after radiotherapy is as effective as the standard radiotherapy plus chemotherapy for high-risk NSMP endometrial cancer, hoping to reduce side effects and improve quality of life.
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MIGHTY: CAR T cells targeting B7-H3 for pediatric, teen, and young adult sarcoma
This Phase 1 trial tests autologous hBRCA84D CAR T cells in kids, teens, and young adults (1–24) with relapsed or refractory RMS, ES, or DSRCT to see if the therapy is feasible and safe.
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Lower-dose ARPI therapy for metastatic prostate cancer
This trial tests whether using half the usual dose of ARPI therapy can work as well as a full dose for men with metastatic prostate cancer who are also receiving standard hormone therapy.
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Treatments for sustained improvement in symptomatic Alzheimer’s disease (18 months)
This trial tests whether adding atomoxetine or metformin to standard care helps people with Alzheimer’s disease or related dementia see lasting improvements over 18 months.
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Impact of an accessory pudendal artery on erection recovery after nerve-sparing prostate surgery
This study checks if preserving an extra artery (the accessory pudendal artery) during robotic prostate removal helps men regain erections after nerve-sparing surgery.
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Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma
This study tests whether safely coagulating small branches of the middle meningeal artery during burr-hole drainage can reduce recurrence of chronic subdural haematoma in adults receiving standard surgical care.
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Urodynamics versus videourodynamics for women with recurrent stress urinary incontinence
This trial will test whether videourodynamics or standard urodynamics before repeat surgery helps women with recurrent stress urinary incontinence get better treatment outcomes.
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LaserSAFE: Quick in OR imaging to check margins during prostatectomy
A new in‑the‑operating‑room imaging method called LaserSAFE is tested to see if it can quickly detect cancer at the edge of the prostate during surgery for patients undergoing robot-assisted prostatectomy.
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Actinium (225Ac) PSMA therapy for castration‑resistant prostate cancer after Lutetium
This trial will test whether an injectable Actinium-225 PSMA treatment can control advanced prostate cancer in men whose disease progressed after Lutetium‑PSMA therapy.
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Anti-CCR9 CAR T-cell therapy for T‑cell acute lymphoblastic leukaemia and lymphoblastic lymphoma
We will try anti-CCR9 CAR T cells made from your own blood to find a dose that is safe for children and adults with relapsed or refractory T‑cell leukaemia or lymphoma.
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Edmond J. Safra Parkinson's multi-arm, multi-stage treatment platform
This project tests whether adding telmisartan or terazosin (versus placebo) helps people with Parkinson's disease who are already taking Parkinson's medications.
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Extended high-dose antibiotics plus methenamine hippurate versus standard low-dose antibiotics or methenamine hippurate for women with chronic urinary tract infection
This study will try longer courses of higher-dose antibiotics together with methenamine hippurate to see if they reduce daily symptoms better than the usual low-dose antibiotics or methenamine in adult women with chronic urinary tract infection.
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Health impact of non-tuberculous mycobacteria (NTM) lung disease
This project will try to see which symptoms matter most and which non-drug treatments help adults with NTM lung disease.
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Optimal treatment duration for radiographically apparent TB without bacteriological confirmation
This trial tests the shortest effective TB treatment duration for people found by community chest X-rays to have TB-like signs but who lack bacteriological confirmation.
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Bespoke Decision Support for Localised Prostate Cancer
Aiming to see if a personalized decision aid helps men with a new localised prostate cancer choose a treatment with less worry or conflict.
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Giving immunotherapy before standard treatment for newly diagnosed glioblastoma
This Phase 1 trial tests whether giving two doses of the immunotherapy drug ipilimumab before surgery is safe and may help people with newly diagnosed glioblastoma or gliosarcoma.
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PRISM: A dashboard to help First Contact Physiotherapists see if patients' MSK pain is suitable for primary care care
A feasibility test to see if a data dashboard can help First Contact Physiotherapists in UK GP practices identify appropriate MSK patients and standardize decisions.
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Using entropy to detect sleep breathing problems in chronic lung disease
This project will test whether entropy measurements from simple overnight oxygen and pulse recordings can find sleep-disordered breathing in adults with chronic lung conditions such as COPD, asthma, bronchiectasis, and interstitial lung disease.
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Finding undiagnosed chronic lung problems in people with other long-term health conditions in Brazil
This project will try two short questionnaires (COLA and SBQ) plus breathing tests to find undiagnosed asthma, COPD, or similar lung problems in people with long-term conditions who attend primary care in São Carlos and São Paulo, Brazil.
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Biomarker-guided decisions about preventive TB treatment
This project tests what influences adults tested for latent TB when deciding whether to start preventive treatment.
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neoSCB app to screen newborns for jaundice
This project will test whether the neoSCB smartphone app can accurately detect significant jaundice in newborn babies by photographing the white part of the eye.
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Robotic Mako cementless versus cemented total knee replacement
This study will test whether robotic Mako cementless or cemented knee replacements work better for adults having a primary total knee replacement for osteoarthritis.
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Adaptive deep brain stimulation for children with Lennox–Gastaut syndrome
This trial will test adaptive deep brain stimulation using the Picostim device to try to reduce seizures in children aged 5–14 with Lennox–Gastaut syndrome.
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Understanding Fuchs' Endothelial Corneal Dystrophy and its Genetic Links
This study is trying to understand how Fuchs' Endothelial Corneal Dystrophy affects younger people with a genetic link to the condition by using advanced imaging to track changes over time.
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Sharing anonymized MRI data for small bowel diseases
This study is sharing MRI scans and related health information from patients with small bowel diseases like Crohn's to see how well these scans can help doctors understand and treat these conditions.
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Digital program to prepare for psychedelic experiences using meditation or music
This study is testing a 21-day digital program using either meditation or music to help healthy people prepare for a psilocybin experience and see how it affects their journey.
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Comparing MR Enterography and Ultrasound for Assessing Crohn's Disease Treatment Response
This study is testing whether MR Enterography or Intestinal Ultrasound is better at showing how well treatment is working for people with Crohn's disease who are 16 and older.
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Understanding antibiotic resistance and microbiome changes in STI prevention
This study is trying to see how using doxycycline for STI prevention affects antibiotic resistance and changes in gut bacteria in men who have sex with men.
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Isatuximab plus iberdomide and dexamethasone for people with intermediate- or high-risk smouldering myeloma
This trial will test whether combining isatuximab, iberdomide, and dexamethasone can delay or prevent progression to active multiple myeloma in adults with intermediate- or high-risk smouldering myeloma.
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Improving pelvic rehabilitation after spinal cord injury with epidural stimulation
This study is testing if using a special device to stimulate the spinal cord can help people with spinal cord injuries improve their bladder and bowel function through pelvic rehabilitation.
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Comparing catheter ablation (cryo, radiofrequency, pulsed field) with medical therapy for people with atrial fibrillation and heart failure.
This study will see if catheter ablation plus optimal heart-failure medicines helps people with atrial fibrillation and heart failure have fewer unplanned heart-failure hospital stays and lower risk of death than medicines alone.
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Exploring how physical activity affects depression
This study is trying to see if doing aerobic exercise can help people with depression feel better compared to those doing stretching and relaxation exercises.
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NIO752 to reduce tau production measured with SILK
This Phase 1 trial will test whether the drug NIO752 lowers production of the tau protein in people with mild to moderate Alzheimer's disease or with genetic APP/PSEN mutations.
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Testing new treatments for metastatic hormone-sensitive prostate cancer
This study is testing if new treatments for metastatic hormone-sensitive prostate cancer can help patients live longer and slow down the cancer compared to standard care.
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Program for better living with non-memory-led dementia
This study tests a support program for caregivers of people with non-memory-led dementias to see if it helps them manage their caregiving challenges better.
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Using smartphone technology to improve care for patients with cirrhosis
This study is testing whether a new smartphone monitoring system can help people with advanced liver disease manage their condition better and avoid hospital visits compared to regular care.
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Remote assessment for people with Parkinson's disease
This study is testing whether an online questionnaire and saliva samples can help people with Parkinson's disease learn about their genetics and find out if they might qualify for future clinical trials.
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Using MRI to predict Crohn's disease relapse after stopping biologics
This study is testing if MRI scans can help predict when people with Crohn's disease might have a relapse after stopping their medication.
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New treatments for pulmonary tuberculosis
This study is testing new combinations of two drugs with existing TB treatments to see if they can help people with pulmonary tuberculosis get better in a shorter time than the usual 24 weeks.
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Combination of drugs for treating relapsed large B-cell lymphoma before and after CAR-T therapy
This study is testing a combination of three drugs to see if they can help people with relapsed large B-cell lymphoma feel better before and after CAR-T therapy.
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Using spinal cord stimulation to improve upper limb rehabilitation
This study is testing if adding a gentle spinal cord stimulation treatment to regular rehab can help people with recent spinal cord injuries improve their arm function and reduce stiffness.
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Developing new MRI techniques using healthy volunteers
This study is testing new MRI techniques using healthy volunteers to see if they can make scans faster and better for future medical use.
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Evaluating new biomarkers for lung health checks
This study is testing new biological markers in people getting lung health checks to see if they can help find serious lung cancers earlier and reduce unnecessary treatments.
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Understanding why CAR T cells don't last in leukemia treatment
This study looks at kids and young adults with leukemia to see why CAR T cells don't stick around long enough after treatment and what might help them last longer.
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Using ambroxol to slow down Parkinson's disease progression
This study is testing if ambroxol, a medication usually for breathing problems, can help slow down the progression of Parkinson's disease in people over two years.
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Selective stimulation of the vagus nerve using electrical impedance tomography
This study is testing a new way to stimulate the vagus nerve to see if it can help treat conditions like epilepsy with fewer side effects.
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Proton therapy for treating malignant pleural mesothelioma
This study is testing if proton therapy can help people with malignant pleural mesothelioma live longer and feel better compared to standard care.
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Combining Zanubrutinib and Rituximab for Indolent Mantle Cell Lymphoma
This study is testing if a new combination of two medications, zanubrutinib and rituximab, can help people with indolent mantle cell lymphoma who haven't been treated before.
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Tracking lung cancer evolution through therapy
This study is trying to see how lung cancer changes during treatment in people with different types of the disease by collecting health information and samples over two years.
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Comparing hemithyroidectomy and total thyroidectomy for low-risk thyroid cancers
This study is testing whether a less extensive thyroid surgery is just as effective as a full thyroid removal for people with low-risk thyroid cancer.
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CAR T cell therapy targeting GD2 for treating Diffuse Midline Glioma in children
This study is testing a new treatment using modified immune cells to see if it can help children and young adults with Diffuse Midline Glioma feel better and fight their cancer.
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Understanding why OCD therapy fails
This study is trying to understand why therapy sometimes doesn't work for people with OCD by looking at their brain activity and behavior before and after treatment.
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Nicotinamide treatment for open-angle glaucoma
This study is testing if a form of Vitamin B3 called Nicotinamide can help people with early to moderate open-angle glaucoma keep their vision from getting worse.
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KCAT19 T cells for relapsed or refractory B cell cancers
This study tests KCAT19 T cells, a gene-modified cell therapy, in adults with high-risk B cell cancers that have come back or stopped responding to treatment.
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Impact of a preoperative exercise program on patients awaiting bariatric surgery
This study tests if a four-week exercise program can help people getting ready for bariatric surgery improve their fitness, metabolism, and weight.
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Combination of pembrolizumab and lenvatinib for liver cancer treatment
This study is testing whether a combination of two cancer drugs, pembrolizumab and lenvatinib, can help patients with liver cancer have better outcomes after surgery.
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Gene therapy for children with Ornithine Transcarbamylase deficiency
This study is testing a new gene therapy for children with Ornithine Transcarbamylase deficiency to see if it can help their liver produce a missing enzyme and reduce dangerous ammonia levels in their blood.
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Adaptive chemotherapy approach for relapsed ovarian cancer
This study is testing if adjusting the dose of carboplatin based on a blood marker can help women with relapsed ovarian cancer feel better and have fewer side effects from treatment.
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AI-assisted colonoscopy for diagnosing colorectal polyps
This study is testing whether using an AI device during colonoscopy can help doctors find small colorectal polyps more accurately compared to a regular colonoscopy.
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Liver biopsy for patients with severe hemophilia after gene therapy
This study is testing how gene therapy affects the liver in people with severe hemophilia who have already received the treatment, to learn more about its safety and effectiveness.
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Modular BCMA and BCMA/CD19 CAR T therapy for relapsed or refractory multiple myeloma
This Phase 1 trial will test two CAR T approaches—BCMA-only and BCMA-plus-CD19—in adults with relapsed or refractory multiple myeloma who have had at least three prior treatments.
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Brentuximab vedotin for early stage Hodgkin lymphoma treatment
This study is testing if adding a new drug called brentuximab vedotin to standard chemotherapy can help people with early-stage Hodgkin lymphoma do better in their treatment.
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Mapping lymph nodes in oropharyngeal cancer patients
This study is testing a new way to find important lymph nodes in patients with oropharyngeal cancer to see if it can help doctors make better treatment choices and avoid unnecessary side effects.
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Improving outcomes for patients with osteosarcoma
This study is trying to gather information and samples from people with osteosarcoma to better understand the disease and find ways to improve treatment and outcomes.
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Combination of Durvalumab and Cancer Vaccine for Bladder Cancer
This study is testing a new combination of a cancer vaccine and an immune therapy to see if it can help people with bladder cancer that hasn't responded to standard treatment.
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Comparing two methods of knee replacement surgery
This study tests whether a robotic knee replacement surgery works better than a traditional method for people with knee osteoarthritis.
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Comparing two treatment approaches for Waldenström's macroglobulinaemia
This study is testing a new treatment without chemotherapy for people with Waldenström's macroglobulinaemia to see if it works better and is easier on the body than the standard treatment.
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Testing new treatments for kidney cancer after surgery
This study is testing if a new kidney cancer treatment, either by itself or in combination, can help patients stay cancer-free longer after surgery compared to just monitoring their health.
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Collecting cerebrospinal fluid to aid in developing treatments for Huntington's disease
This study is collecting spinal fluid and blood samples from people with Huntington's disease to help find better treatments for the condition.
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Identifying genetic factors in Parkinson's disease families
This study is trying to find new genes that might cause Parkinson's disease in younger people and those with family members who have it, to help improve diagnosis and treatment options.
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Immunotherapy using CAR T-cells for treating high-risk acute lymphoblastic leukaemia
This study is testing a new type of immune therapy using specially modified T-cells to see if it can help children and young adults with high-risk leukemia feel better and stay in remission longer.
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Focal therapy using high-intensity focused ultrasound for prostate cancer
This study is testing whether high-intensity focused ultrasound can effectively treat localized prostate cancer while causing fewer side effects compared to standard treatments.
NIH-funded research (32)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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English Longitudinal Study of Ageing: Renewal to Track Dementia and Healthy Aging
A long-term national study will continue to collect data on aging, health, cognition, and daily living to help understand how aging and Alzheimer’s-related conditions affect people in the UK and beyond.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A computer program helps plan radiation therapy for cervical and head-and-neck cancer patients to make treatments faster and more accurate.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A United Kingdom study is testing AI software that helps plan radiotherapy for cervical and head-and-neck cancer patients to save time and reduce the workload for clinicians in low-resource settings.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A UK research team is testing an AI-based software to automatically outline cancer areas and plan radiation beams to speed up treatment for cervical and head-and-neck cancers in LMICs.
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AI-Powered Radiotherapy Planning for Cervical and Head & Neck Cancer
A new AI tool helps plan radiation therapy for cervical and head-and-neck cancers to save time and reduce the need for specialized staff.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A UK study from University College London uses AI to plan radiotherapy for cervical and head-and-neck cancers to save time and reduce the need for specialized staff, aiming to help patients in LMICs.
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AI-powered radiotherapy planning for cervical and head & neck cancer
A non-randomized study will test an AI system that helps plan radiotherapy for cervical and head & neck cancers to save time and resources in LMICs.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A UK-led study is testing an AI system that helps plan and optimize radiotherapy for cervical and head-and-neck cancer to reduce wait times and required staff.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A new AI-based system helps doctors plan cervical and head-and-neck cancer radiotherapy faster and with less labor, aiming to reach more patients, especially in low- and middle-income countries.
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Advancing Behavioral Cancer Prevention with Ontology Tools
This project develops and expands a semantic tool (BCIO) to improve clarity and consistency in cancer prevention research that focuses on behavior change.
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AI-assisted radiotherapy planning for cervical and head and neck cancer
This project uses artificial intelligence to create radiotherapy treatment plans faster and with fewer specialists for people with cervical or head and neck cancers, especially in low- and middle-income countries.
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AI-assisted radiotherapy planning for cervical and head and neck cancers
This project uses artificial intelligence to create radiotherapy treatment plans faster and with less specialist time for people with cervical and head and neck cancers, especially in low- and middle-income countries.
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AI-guided radiotherapy planning for cervical and head and neck cancer
This project uses artificial intelligence to speed up and standardize radiation treatment planning for people with cervical or head and neck cancer, especially in low- and middle-income countries.
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AI-assisted radiotherapy planning for cervical and head and neck cancer
This project uses artificial intelligence to make radiotherapy planning faster and more accurate for people with cervical or head and neck cancer, especially in low- and middle-income countries.
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AI-assisted radiotherapy planning for cervical and head and neck cancer
This project uses artificial intelligence to speed up and improve radiotherapy planning for people with cervical or head and neck cancer, especially in areas with limited specialist staff.
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AI-powered radiotherapy planning for cervical and head and neck cancer
This project uses AI software to create radiation treatment plans more quickly and accurately for people with cervical or head and neck cancer, especially in low- and middle-income countries.
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AI-guided radiation planning for cervical and head and neck cancers
AI software creates radiation treatment plans faster and with less staff for people with cervical or head and neck cancer.
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AI-powered radiotherapy planning for cervical and head and neck cancer
This project uses artificial intelligence to create faster, accurate radiotherapy plans for people with cervical or head and neck cancer so more patients can get timely treatment.
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English Longitudinal Study of Ageing renewal to study aging, health, and dementia
A long-running study in older adults is being renewed to collect more data on aging, health, and brain changes, including dementia, so researchers can better understand what affects healthy aging.
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Tracking health, thinking, and daily life in older adults in England
Regularly collects health, memory, daily-activity and social information from older adults in England so researchers can learn what leads to dementia and healthier aging.
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Why some brains resist tau-related damage in Alzheimer's and related dementias
Researchers are using genetically diverse mice that carry a human tau mutation to find genes that help brains resist the tau changes behind Alzheimer's and related dementias.
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AI-assisted radiotherapy planning for cervical and head and neck cancer
This project uses artificial intelligence to speed up and improve radiotherapy plans for people with cervical or head and neck cancer.
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English Longitudinal Ageing (ELSA) — waves 12–13 and HCAP
Collects health, memory, activity, and social information from adults aged 50+ in England to track aging and dementia risk over time.
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Investigating genetic factors that influence resilience to tau-related brain diseases.
This study is looking at how our genes might help some people be more resilient to tau-related issues in Alzheimer's and similar conditions, using special mice to find clues that could lead to new treatments or ways to prevent these diseases.
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Creating a large database of T cell receptors and their interactions with cancer antigens
This study is looking at how certain immune cells recognize cancer markers, which could help create better treatments for cancer patients using their own immune systems.
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Targeting protein degradation to treat childhood tumors
This study is working on new and better treatments for kids with solid tumors, especially brain tumors, by focusing on specific proteins that help these tumors grow, so that young patients can have more effective options beyond the usual chemotherapy and radiation.
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Improving cancer prevention through better understanding of behavior change.
This study is working on a way to make it easier for researchers to share and understand how different behaviors, like quitting smoking or being more active, can help prevent cancer, so they can create better tools to support people in making healthy changes.
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Using Natural Killer cells to fight HIV and HBV co-infection
This study is looking at how special immune cells called Natural Killer (NK) cells can help improve treatment for people who have both HIV and Hepatitis B, by exploring how these cells work in the body to fight off the viruses.
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Using AI to improve radiotherapy planning for cervical and head and neck cancers
This study is testing a new AI tool to make planning radiation treatment for cervical and head and neck cancers faster and easier, so patients can get the care they need more quickly, especially in places where resources are limited.
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New T cell therapies for childhood cancers
This study is working on creating special treatments using T cells to help kids with tough-to-treat solid cancers, like certain types of sarcomas and brain tumors, by making these immune cells better at finding and fighting cancer cells.
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Investigating how cancer cells use circular DNA to grow and resist treatment
This study is looking at a special type of DNA found in some cancers that helps tumors grow and resist treatment, and it's aimed at finding new ways to help patients with these tumors get better care.
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Understanding and addressing cancer cachexia
This study is looking into cancer cachexia, a tough condition that causes weight loss and muscle loss in many cancer patients, to understand how tumors affect the body's metabolism, with the hope of finding better treatments to help improve patients' lives.
Quick answers
How many clinical trials run by University College, London are recruiting right now?
73, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 24 countries. The most sites are in United Kingdom (70 trials), United States (4 trials), Canada (3 trials), Germany (2 trials), New Zealand (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 10, Phase 1: 9, Phase 2: 7, Phase 1/2: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.