NIH-funded research U01 cooperative agreement

AI-powered radiotherapy planning for cervical and head and neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11399430 · Data updated 2026-11-12

This project uses AI software to create radiation treatment plans more quickly and accurately for people with cervical or head and neck cancer, especially in low- and middle-income countries.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$40,177
NIH project number3U01CA269143-03S3
Project IDNIH-11399430 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people diagnosed with cervical or head and neck cancer who are scheduled for CT-based radiotherapy planning at one of the participating treatment centers.

Less likely to help

People with cancers other than cervical or head and neck, those not receiving radiotherapy, or those treated at non-participating centers are unlikely to be helped by this project.

What this research studies

If I join, researchers will use AI software to draw the tumor and nearby organs on my CT scans and to design the radiation beams needed to treat me. They plan a non-randomized, prospective study enrolling about 706 patients split between cervical and head and neck cancer to see if AI plans meet clinical standards and reduce planning time. The team will compare AI-generated plans to usual human-made plans for quality, safety, workflow time, and cost. The goal is to shorten planning from weeks to under a day so more patients in low- and middle-income countries can get timely curative radiotherapy.

Why it matters

Potential benefit: If successful, this could allow faster, accurate radiotherapy plans so more patients—especially in low- and middle-income countries—get timely curative treatment.

How similar studies have gone: Previous studies of AI auto-contouring and treatment-planning tools have often sped up workflows and produced plans comparable to human planners in high-resource settings, but large prospective trials in low- and middle-income countries remain limited.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.