NIH-funded research U01 cooperative agreement

AI-powered radiotherapy planning for cervical and head-and-neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11535417 · Data updated 2026-11-12

A UK research team is testing an AI-based software to automatically outline cancer areas and plan radiation beams to speed up treatment for cervical and head-and-neck cancers in LMICs.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$3,927
NIH project number3U01CA269143-04S5
Project IDNIH-11535417 on NIH RePORTER

Who could benefit from this research

Could help

Patients with cervical cancer or head-and-neck cancer who are candidates for radiotherapy at participating centers.

Less likely to help

Patients whose tumors or anatomy are not suitable for AI-generated planning or who require personalized manual planning.

What this research studies

This project from University College London will test an AI system that automates key steps in radiotherapy planning, aiming to shorten planning time and reduce the need for highly specialized staff. It is a non-randomized prospective study enrolling patients with cervical cancer or head-and-neck cancer to see how well the AI-generated plans compare to standard methods and whether they reduce costs. Researchers will measure plan quality, treatment accuracy, and economic impact across up to 706 participants. If successful, the system could help LMICs provide timely radiotherapy to more patients with fewer clinicians.

Why it matters

Potential benefit: If successful, patients could receive accurate radiotherapy plans faster, potentially improving outcomes and expanding access in resource-limited settings.

How similar studies have gone: Previous AI planning efforts show promise in speeding planning and maintaining quality, but this exact LMIC-focused approach is being evaluated.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.