NIH-funded research U01 cooperative agreement

AI-powered radiotherapy planning for cervical and head-and-neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11535418 · Data updated 2026-11-12

A United Kingdom study is testing AI software that helps plan radiotherapy for cervical and head-and-neck cancer patients to save time and reduce the workload for clinicians in low-resource settings.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$10,654
NIH project number3U01CA269143-04S6
Project IDNIH-11535418 on NIH RePORTER

Who could benefit from this research

Could help

Patients with cervical cancer or head-and-neck cancer who are candidates for radiotherapy and treated at participating centers.

Less likely to help

Patients not receiving radiotherapy or treated outside participating sites may not benefit.

What this research studies

This project uses artificial intelligence to automatically outline risky anatomy and shape radiation beams for cervical and head-and-neck cancers. It is a non-randomized, prospective study conducted at University College London to see how well the AI-based planning matches expert plans and what it costs in real-world use. The goal is to speed up treatment planning from weeks to potentially under a day while preserving accuracy and safety. If successful, the approach could expand access to radiotherapy in low- and middle-income countries by reducing the need for specialized staff and resources.

Why it matters

Potential benefit: If successful, patients could receive faster and potentially more consistent radiotherapy planning, increasing access to curative treatment in resource-limited settings.

How similar studies have gone: Previous AI-assisted radiotherapy planning work has shown promise in improving efficiency and planning quality, though the LMIC context and non-randomized design are important factors here.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.