Understanding and addressing cancer cachexia

CANcer Cachexia Action Network/CANCAN

NIH-funded research University College London · NIH-10627283

This study is looking into cancer cachexia, a tough condition that causes weight loss and muscle loss in many cancer patients, to understand how tumors affect the body's metabolism, with the hope of finding better treatments to help improve patients' lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity College London NIH-funded
Lab location1 site (London, United Kingdom)
Project IDNIH-10627283 on NIH RePORTER

What this research studies

This research focuses on cancer cachexia, a serious condition affecting around 80% of cancer patients, characterized by significant weight loss and muscle wasting. The project aims to uncover the underlying mechanisms driving this syndrome by studying the interactions between tumors and the body's metabolism. A diverse team of international experts will utilize advanced techniques to analyze metabolic changes and identify potential therapeutic targets. The goal is to develop effective treatments that can improve patients' quality of life and treatment outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients experiencing significant weight loss and muscle wasting due to their illness.

Not a fit: Patients who are not currently diagnosed with cancer or who do not exhibit symptoms of cachexia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective therapies for cancer cachexia, improving survival and quality of life for cancer patients.

How similar studies have performed: While there has been extensive research on cancer cachexia, this approach aims to fill critical gaps in understanding and has the potential to lead to novel therapeutic strategies.

Where this research is happening

London, United Kingdom

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions cancer cachexiacancer associated cachexiacancer induced cachexiacancer-associated muscle wastingcancer-induced muscle atrophy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.