NIH-funded research U01 cooperative agreement

AI-powered radiotherapy planning for cervical and head & neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11535414 · Data updated 2026-11-12

A non-randomized study will test an AI system that helps plan radiotherapy for cervical and head & neck cancers to save time and resources in LMICs.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$18,091
NIH project number3U01CA269143-04S2
Project IDNIH-11535414 on NIH RePORTER

Who could benefit from this research

Could help

Patients with cervical cancer or head and neck cancer who are treated with radiotherapy.

Less likely to help

Patients not receiving radiotherapy or those with cancers outside cervical or head and neck sites may not benefit.

What this research studies

This project from University College London tests an AI-based software that automates two key steps in radiotherapy planning: outlining regions at risk and shaping radiation beams. It aims to shorten planning time from weeks to under a day and reduce the need for highly specialized staff in low- and middle-income countries. The study will enroll about 706 patients with cervical or head & neck cancer to evaluate plan quality and the economic impact of the AI workflow. Participation would involve standard radiotherapy planning processes and data collection within clinical care. Results could guide scalable, more accessible radiotherapy in settings with workforce shortages.

Why it matters

Potential benefit: If successful, the AI tool could make radiotherapy faster and more affordable for many patients.

How similar studies have gone: Previous AI-based radiotherapy planning work suggests potential improvements in accuracy and efficiency, but large LMIC-focused prospective data are needed.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.