Clinical trial Recruiting at 1 site Observational Ages Any age to 28 Days

neoSCB app to screen newborns for jaundice

Official title: Clinical Investigation of the Smartphone App neoSCB to Perform Neonatal Jaundice Screening in Newborn Babies

Run by University College, London · NCT06963450 · Data updated 2026-11-12

This project will test whether the neoSCB smartphone app can accurately detect significant jaundice in newborn babies by photographing the white part of the eye.

Quick facts

Study typeObservational
AgesAny age to 28 Days
SexAll
Enrollment405 (estimated)
SponsorUniversity College, London
Academic / other
Locations1 site (London)
StatusRecruiting
StartedSeptember 23, 2025
Main results expectedMarch 31, 2027
Study endsMarch 31, 2027
Registry record updatedDecember 4, 2025
Trial IDNCT06963450 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Term newborns aged 0–28 days who are clinically stable and have not recently received phototherapy are the intended participants.

Probably not a fit

Infants who are clinically unwell, require urgent medical attention, are preterm, or have recently received phototherapy are excluded and unlikely to benefit from this screening approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational project that takes smartphone photos of a newborn's sclera and applies a diagnostic algorithm to quantify yellowness as a marker of jaundice. Term infants up to 28 days old, with or without visible jaundice, will have scleral photographs taken and may undergo routine bilirubin testing as clinically required. The approach aims to reduce unnecessary hospital blood tests driven by imperfect visual inspection and to help identify infants needing timely treatment. The study is conducted at University College London Hospitals and builds on prior validation work in Ghana.

Why it matters

Potential benefit: If successful, the app could enable quicker, more accurate screening for significant neonatal jaundice, reducing unnecessary blood draws and helping ensure earlier treatment when needed.

How similar studies have gone: The neoSCB app has previously been validated in Ghana with over 700 newborns and demonstrated promising accuracy compared with standard bilirubin testing.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Term newborn babies with and without jaundice (postnatal age 0 day to 28 days)

Exclusion Criteria:

* Newborn babies who are clinically unwell and require urgent medical attention, and babies who have received phototherapy recently

Where it's running

  • UCL Hospitals
    London, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.