NIH-funded research U01 cooperative agreement

AI-assisted radiotherapy planning for cervical and head and neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11176033 · Data updated 2026-11-12

This project uses artificial intelligence to speed up and improve radiotherapy plans for people with cervical or head and neck cancer.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$215,448
NIH project number5U01CA269143-03
Project IDNIH-11176033 on NIH RePORTER

Who could benefit from this research

Could help

Adults with a diagnosis of cervical or head and neck cancer who are scheduled to receive curative radiotherapy at a participating center would be the ideal candidates.

Less likely to help

Patients with other cancer types, those not receiving radiotherapy, or people treated outside participating sites are unlikely to be eligible or to benefit directly from this project.

What this research studies

This project will use AI software to automatically outline tumor areas and nearby organs and to define the radiation beam shapes for patients needing radiotherapy for cervical or head and neck cancer. Doctors will run a prospective study of about 706 patients to compare AI-generated plans with usual manual planning to judge plan quality, time, and cost. The aim is to cut planning time from weeks to under a day and reduce dependence on scarce specialist staff, especially in low- and middle-income countries. If AI plans are shown to be safe and acceptable, the approach could be adopted more widely to speed treatment starts.

Why it matters

Potential benefit: Could greatly reduce waiting times and expand access to timely, accurate radiotherapy for patients in low- and middle-income countries.

How similar studies have gone: Previous pilot studies of AI auto-contouring and planning have shown promise in speeding workflows, but large prospective validation in LMIC settings remains limited.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.