NIH-funded research U01 cooperative agreement

AI-assisted radiotherapy planning for cervical and head and neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11399431 · Data updated 2026-11-12

This project uses artificial intelligence to speed up and improve radiotherapy planning for people with cervical or head and neck cancer, especially in areas with limited specialist staff.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$24,653
NIH project number3U01CA269143-03S4
Project IDNIH-11399431 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people diagnosed with cervical or head and neck cancers who are scheduled to receive radiotherapy at a participating center, especially in low- and middle-income countries.

Less likely to help

People with other types of cancer, those not receiving radiotherapy, or patients treated outside participating sites are unlikely to receive direct benefit from this project.

What this research studies

This project will use software that automatically outlines tumor and nearby organs on CT scans and creates radiation beam plans so doctors can treat cervical and head and neck cancers faster. It is a non-randomized prospective study enrolling about 706 patients (353 per cancer type) to compare the quality and economic impact of AI-generated plans with current clinical practice. The team aims to reduce planning time from weeks to less than a day and lower the need for specialized workforce. Data will be collected at participating cancer centers, particularly in low- and middle-income countries, to evaluate real-world performance and feasibility.

Why it matters

Potential benefit: If successful, this could make radiotherapy faster, more accurate, and much more available in areas with few specialist staff.

How similar studies have gone: Previous AI tools for automatic contouring and treatment planning have shown promising accuracy and speed in pilot and single-center studies, but larger multi-center real-world evaluations are still needed.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.