NIH-funded research U01 cooperative agreement

AI-powered radiotherapy planning for cervical and head-and-neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11535413 · Data updated 2026-11-12

A UK-led study is testing an AI system that helps plan and optimize radiotherapy for cervical and head-and-neck cancer to reduce wait times and required staff.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$70,126
NIH project number3U01CA269143-04S1
Project IDNIH-11535413 on NIH RePORTER

Who could benefit from this research

Could help

Patients with cervical cancer or head-and-neck cancer who are candidates for radiotherapy and treated in LMICs or similar resource settings.

Less likely to help

Patients whose tumors are not amenable to AI-generated planning or who are not receiving radiotherapy.

What this research studies

This project uses artificial intelligence to automatically outline critical anatomy and design radiation beams for two common cancer types. It aims to shorten planning time from weeks to under a day and lessen the need for highly specialized staff in low- and middle-income countries. The study will follow patients treated with AI-generated plans to see if the results meet quality standards and to understand the economic impact. It is a non-randomized prospective study conducted at a major international center to evaluate real-world use of AI in radiotherapy planning.

Why it matters

Potential benefit: If successful, patients could receive faster, accurate radiotherapy with less dependence on scarce specialized staff.

How similar studies have gone: Previous AI planning tools have shown promise in improving planning efficiency and consistency in some settings, though prospective LMIC-focused data are limited.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.