Biomarker-guided decisions about preventive TB treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study uses two stages: first, up to 30 semi-structured interviews with adults who have been or are being tested for latent TB infection as part of routine clinical screening. Findings from the qualitative interviews will be used to design a discrete choice experiment (DCE). The DCE will quantify how patients and healthcare providers trade off future TB risk against attributes of preventive treatment when making decisions. Participants will be purposively sampled to include migrants from high-incidence countries, recent TB contacts, and people screened before immunosuppression or via occupational health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (aged ≥18 years) who have been tested for latent TB infection in routine clinical services, or are eligible for testing. Eligible people for testing include migrants from countries with high TB incidence (entered UK within 5 years), people with recent contact with a person with TB disease, and people eligible for LTBI screening prior to starting immunosuppression or through occupational health testing.

Exclusion Criteria:

* Unable to provide informed consent.

Where it's running

• Whittington Hospital
  London, United Kingdom Recruiting

Study contacts

• Study coordinator: Rishi K Gupta, PhD
• Email: r.gupta@ucl.ac.uk
• Phone: 020 3549 5979

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.