Evaluating new biomarkers for lung health checks

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess novel biomarkers in participants undergoing targeted lung health checks, particularly focusing on low-dose CT screening for lung cancer. The study seeks to improve the identification of clinically significant lung cancers by integrating biomarker analysis from minimally invasive samples with traditional imaging techniques. By addressing the challenges of distinguishing between benign and malignant nodules, the research hopes to enhance early detection and reduce unnecessary treatments. Participants will be recruited from the NHS Targeted Lung Health Check program.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Attended one of more visits as part of the NCL NHS TLHC programme
* Adults aged between 55 years and 74 years and 364 days
* Have capacity and can provide written consent

Exclusion Criteria:

* Declines participation in ALPINE
* Lacking capacity and unable to provide written consent
* Patients who are considered by the clinician to be unfit/not suitable for enrolment in ALPINE

Where it's running

• University College London Hospitals NHS Foundation Trust
  London, United Kingdom Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.