NIH-funded research U01 cooperative agreement

AI-guided radiation planning for cervical and head and neck cancers

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11399429 · Data updated 2026-11-12

AI software creates radiation treatment plans faster and with less staff for people with cervical or head and neck cancer.

More Head and Neck Cancer research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$6,111
NIH project number3U01CA269143-03S2
Project IDNIH-11399429 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people scheduled to receive curative radiotherapy for cervical or head and neck cancer at the trial's participating clinical centers.

Less likely to help

Patients with cancers other than cervical or head and neck tumors, or those requiring highly individualized planning outside the AI's scope, may not benefit.

What this research studies

This project uses AI to automate two key steps in radiotherapy planning: outlining anatomy at risk and defining beam size and position, so plans can be ready in hours instead of weeks. You or others needing curative radiotherapy for cervical or head and neck cancer at participating centers will have CT scans processed by the AI and the AI-generated plans reviewed by clinicians. The non-randomized prospective study aims to enroll about 706 patients (353 per cancer type) to compare plan quality, timesaving, and economic impact of the AI workflow. The goal is to make safe, accurate radiotherapy planning more available in low- and middle-income countries where specialist staff are scarce.

Why it matters

Potential benefit: If successful, this could speed access to radiotherapy, reduce planning costs and staff needs, and expand treatment capacity in low- and middle-income countries.

How similar studies have gone: Previous pilot work on AI auto-contouring and automated planning has shown promising time savings and acceptable plan quality, but larger prospective trials are still limited.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.