NIH-funded research U01 cooperative agreement

AI-powered radiotherapy planning for cervical and head-and-neck cancer

Official title: ARCHERY: Artificial Intelligence based Radiotherapy treatment planning for Cervical and Head and Neck cancer

Funded at University College London · NIH-11415643 · Data updated 2026-11-12

A new AI-based system helps doctors plan cervical and head-and-neck cancer radiotherapy faster and with less labor, aiming to reach more patients, especially in low- and middle-income countries.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity College London
NIH-funded
Lab location1 site (London, United Kingdom)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$163,987
NIH project number5U01CA269143-04
Project IDNIH-11415643 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with cervical cancer or head-and-neck cancer who are candidates for radiotherapy and treated at participating LMIC-priority centers.

Less likely to help

Patients whose tumors are outside the targeted sites or who require alternative treatment modalities may experience no direct benefit.

What this research studies

This project from University College London develops AI software to automatically outline critical anatomy and to define radiation beam positions for cervical and head-and-neck cancers. It will be tested in a non-randomized, prospective study involving about 706 patients to measure how well the AI plans match expert standards and how the technology impacts costs. If successful, the approach could shorten planning time from weeks to under a day and reduce the need for specialized staff, potentially increasing access to radiotherapy in LMICs. The study will focus on improving treatment accuracy while lowering resource requirements in high-need settings.

Why it matters

Potential benefit: If successful, patients could receive timely, accurate radiotherapy with less dependence on scarce workforce resources.

How similar studies have gone: Preliminary AI planning tools have shown promise in improving planning efficiency, but this exact approach in LMIC settings is still being evaluated.

Where this research is happening

  • University College London
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Aggarwal, Ajay — University College London
  • Study coordinator: Aggarwal, Ajay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.