Identifying genetic factors in Parkinson's disease families

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify new genes that predispose individuals to Parkinson's Disease and Parkinsonism by examining the genetic makeup of affected individuals and their family members. The focus is on two specific groups: those who developed Parkinson's before the age of 45 and those with a family history of the disease. By studying these familial connections, researchers hope to uncover genetic variations that contribute to the condition, which could lead to improved diagnosis and targeted treatments. The study seeks to enhance understanding of the disease's genetic underpinnings and potentially develop interventions that can be applied earlier in the disease process.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Clinical diagnosis of Parkinson's disease or parkinsonism, and either family history of Parkinson's/parkinsonism (first or second degree family member affected by Parkinson's or parkinsonism) AND/OR Early onset Parkinson's/parkinsonism (symptom onset before the age of 45 years) First or second degree family member of an Index Case, affected or unaffected by Parkinson's/parkinsonism.

Aged over 16 years

Exclusion Criteria:

Lack of capacity to consent to participate in the project.

Where it's running

• Royal Free London NHS Foundation Trust
  London, United Kingdom Recruiting
• University College London Hospitals NHS Foundation Trust
  London, United Kingdom Recruiting

Study contacts

• Principal investigator: Huw Morris, PhD, FRCP — University College, London
• Study coordinator: Study Coordinator
• Email: ion.pdresearch@ucl.ac.uk
• Phone: 02080168174

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.