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Clinical trials and research at Loma Linda University

• 33Clinical trials
• 33NIH research projects
• 1Country

Newest trials

All recruiting trials (33)

• See if extra prenatal breastfeeding education helps moms in Inland Empire breastfeed exclusively

  This study tests whether supplemental breastfeeding education during pregnancy increases exclusive breastfeeding at 6 weeks after birth for first-time moms or those who didn’t breastfeed long in the past.

  Recruiting Loma Linda University · Loma Linda, California · NCT07560553

• Shoulder strength in baseball players with retroverted shoulders

  This study tests how biological age vs. chronological age affects shoulder strength in healthy baseball players to inform injury prevention.

  Recruiting Loma Linda University · Loma Linda, California · NCT07209423

• Comparing two surgical techniques for testicular cancer treatment

  This study is testing if a new surgical method for treating testicular cancer can help patients feel less pain and need fewer pain medications after surgery compared to the standard method.

  Recruiting at 2 sites Loma Linda University · Loma Linda, California and 1 other locations · NCT06828185

• Occupational therapy program for adults affected by intimate partner violence

  This program will try eight occupational therapy sessions to see if they help adults in a domestic violence shelter improve daily activities and coping.

  Recruiting Loma Linda University · Loma Linda, California · NCT06808828

• Examining gum changes after removing an implant crown

  This study is testing how the gums change after taking off an implant crown to see how long it takes for those changes to happen, which is important for making new crowns look good.

  Recruiting Loma Linda University · Loma Linda, California · NCT06783595

• Effects of suctioning on pain and stress in intubated ICU patients

  This study is testing if suctioning the breathing tube in ICU patients causes more pain and stress compared to not suctioning.

  Recruiting Loma Linda University · Loma Linda, California · NCT06692400

• Comparing muscle response monitoring using median and ulnar nerves during surgery

  This study is testing if monitoring muscle responses from the median nerve during surgery is just as good as using the ulnar nerve for people under general anesthesia.

  Recruiting Loma Linda University · Loma Linda, California · NCT06553131

• Helping pregnant women quit smoking with community health workers

  This study is testing a new program that uses community health workers to help pregnant women in San Bernardino County quit smoking by providing support through home visits.

  Recruiting Loma Linda University · Loma Linda, California and 1 other locations · NCT06438549

• Comparing diluted povidone-iodine and saline to reduce surgical site infections

  This study is testing whether using diluted povidone-iodine instead of saline during surgery can help prevent infections in patients having emergency abdominal surgery.

  Recruiting Phase 3 Loma Linda University · Loma Linda, California · NCT06363877

• Comparing saline and chlorhexidine for wound irrigation after cesarean delivery

  This study is testing whether using saline or a special antiseptic solution helps wounds heal better after a cesarean delivery.

  Recruiting Loma Linda University · Loma Linda, California · NCT06339203

• Effects of intermittent fasting on body fat and quality of life

  This study is testing if intermittent fasting can help healthy people lose body fat and feel better in their daily lives.

  Recruiting Loma Linda University · Loma Linda, California · NCT06307275

• Evaluating how physician attire affects patient trust

  This study looks at how the way doctors dress affects how much trust patients feel towards them in a hospital setting.

  Recruiting Loma Linda University · Loma Linda, California · NCT06125431

• Understanding sleep's impact on auditory processing in children with autism

  This study is trying to see how sleep problems affect hearing skills in children with autism by comparing those who have Central Auditory Processing Disorder to those who don’t.

  Recruiting Loma Linda University · Loma Linda, California · NCT06059352

• Health and resiliency programs for occupational therapy students

  This study is testing if adding health and resiliency programs to the coursework helps occupational therapy students feel better about themselves and improve their mental well-being.

  Recruiting Loma Linda University · Loma Linda, California · NCT05956756

• Comparing two doses of Aspirin for preventing strokes in patients with blunt cerebrovascular injury

  This study tests whether a lower dose of Aspirin can prevent strokes just as well as a higher dose in adults with blunt cerebrovascular injury.

  Recruiting Phase 4 Loma Linda University · Loma Linda, California · NCT05868525

• Team-based intervention for HIV care in hospitals

  This study tests if a team-based support program can help newly diagnosed HIV patients get the care they need while in the hospital and reduce their chances of coming back to the hospital.

  Recruiting Loma Linda University · Loma Linda, California · NCT05866523

• Comparing walking with powered and passive prosthetic knees for amputees

  This study tests whether walking with a powered prosthetic knee is easier and more efficient for people with leg amputations compared to using a standard knee.

  Recruiting Loma Linda University · Loma Linda, California · NCT05831696

• Comparing two methods for treating diabetic peripheral neuropathy

  This study is testing whether a new therapy called Intraneural Facilitation Therapy works better than standard physical therapy for treating nerve pain in people with Type 2 diabetes.

  Recruiting Loma Linda University · Loma Linda, California · NCT05577390

• Comparing outcomes of lateral pharyngoplasty with tonsillectomy in children

  This study tests if adding a throat surgery called lateral pharyngoplasty to tonsil removal helps children recover better and feel less pain after their operation.

  Recruiting Loma Linda University · Murrieta, California and 3 other locations · NCT05575401

• Comparing Nifedipine and Labetalol for postpartum high blood pressure

  This study is testing whether the medication Nifedipine or Labetalol works better to lower high blood pressure in women after giving birth.

  Recruiting Phase 3 Loma Linda University · Loma Linda, California · NCT05551104

• Improving family resilience for children with adverse childhood experiences

  This study is testing a new support program for families with children aged 3 to 11 who have faced tough experiences, to see if it helps improve their health and well-being.

  Recruiting Loma Linda University · Loma Linda, California · NCT05388864

• Investigating how limited ankle movement affects squats in people with knee pain

  This study is testing if improving ankle movement can help people with knee pain do single limb squats better.

  Recruiting Loma Linda University · Loma Linda, California · NCT05285007

• Understanding social cognition deficits in autism and psychosis

  This study is testing how a social skills program can help improve social understanding in teenagers with autism and those with schizophrenia, while also looking at how their brains work differently.

  Recruiting Loma Linda University · Loma Linda, California · NCT05185128

• Using donor-derived DNA and immune cells to predict kidney transplant rejection

  This study is testing if measuring certain DNA and immune cells from kidney donors can help predict if a kidney transplant will be rejected by the recipient's body.

  Recruiting Loma Linda University · Loma Linda, California · NCT05084768

• Non-invasive treatment for piriformis muscle pain

  This study is testing a new non-invasive treatment for people with piriformis muscle pain to see if it helps reduce their pain compared to a sham treatment.

  Recruiting Loma Linda University · Loma Linda, California · NCT05023005

• Impact of Magnesium Sulfate on Nerve Monitoring During Surgery

  This study is testing if giving magnesium sulfate during spine and brain surgeries can improve nerve monitoring and pain management compared to a placebo.

  Recruiting Phase 4 Loma Linda University · Loma Linda, California · NCT04938765

• Using gabapentin before wisdom teeth removal to reduce pain and opioid use

  This study tests if taking gabapentin before getting your wisdom teeth removed can help manage pain and reduce the need for opioids during recovery.

  Recruiting Phase 4 Loma Linda University · Loma Linda, California · NCT04860141

• Effects of melatonin on sleep in adolescents

  This study is testing if giving melatonin to teenagers aged 13 to 17 who have trouble sleeping can help them sleep better and feel more alert during the day.

  Recruiting Loma Linda University · Loma Linda, California and 1 other locations · NCT04588233

• Reducing radiation exposure during sacral neuromodulation lead placement

  This study tests if using lower radiation settings during sacral neuromodulation lead placement can help keep patients with overactive bladder safe while still getting the procedure done correctly.

  Recruiting Loma Linda University · Loma Linda, California · NCT04527445

• Understanding how Edaravone works in different types of ALS patients

  This study is trying to see how the medication Edaravone affects different types of ALS patients and which ones might benefit the most from it.

  Recruiting Loma Linda University · Loma Linda, California · NCT04097158

• Combining chemotherapy and radiation before surgery for localized pancreatic cancer

  This study is testing if giving chemotherapy and radiation before surgery can help people with localized pancreatic cancer have better chances of completely removing the cancer.

  Recruiting Phase 2 Loma Linda University · Loma Linda, California · NCT03492671

• Using proton therapy to treat liver metastases

  This study is testing if proton therapy can help control hard-to-treat liver metastases better than traditional methods for patients who have limited treatment options.

  Recruiting Loma Linda University · Loma Linda, California · NCT01697371

• Proton therapy for treating esophageal cancer

  This study tests a new treatment for localized esophageal cancer that combines proton therapy with chemotherapy to see if it can work better and cause less harm than traditional methods.

  Recruiting Loma Linda University · Loma Linda, California · NCT01684904

NIH-funded research (33)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• LLU's shared-use facility to advance cellular therapy and regenerative medicine

  A new shared laboratory facility at Loma Linda University will enable cell therapy and regenerative medicine work that could help people with cancer, blood disorders, and immune-related conditions.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11523347

• Brain support cells in newborn brain injury after birth asphyxia

  This grant studies how brain-supporting cells called pericytes affect brain damage after a newborn experiences a lack of oxygen at birth, with potential to guide new treatments.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11482126

• Digitally supported community workers helping HPB cancer patients receive early palliative care

  A pilot program uses digital tools and community health workers to bring early palliative care and support to people with HPB cancers and their caregivers.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11437782

• REASON Score: an epigenetic and clinicopathologic approach to predict survival risk in early oral cancer

  A new biomarker-based score using DNA methylation and clinicopathology to predict survival risk for people with early-stage oral squamous cell carcinoma.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11372175

• Effects of chronic low oxygen on brain blood flow control in newborns

  A study in newborns and animal models will explore how chronic low oxygen affects the brain’s ability to keep blood flow steady, which is crucial for preventing brain injuries.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11341894

• Endothelial potassium channels and brain aging

  A study in mice and aging adults to understand how tiny blood vessels in the brain fail and contribute to dementia, with the goal of identifying targets to protect brain blood flow in people at risk.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11330283

• How low oxygen in pregnancy changes uterine blood flow

  Researchers are learning how low oxygen during pregnancy changes uterine blood flow and how that can affect pregnant people and their babies.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11323619

• How a mother's e-cigarette use might change her baby's brain development

  This work looks at whether a mother's e-cigarette use during pregnancy can change gene activity in the developing brain and lead to problems like ADHD, anxiety, or learning and behavior issues.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11258038

• PEDF protein to protect the brain after aneurysmal subarachnoid hemorrhage

  This work looks at whether a natural protein called PEDF can protect the brain and its blood vessels after bleeding from a brain aneurysm.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11232362

• Finding gene changes in individual leukemia cells for better diagnosis

  This project is developing a new, more precise way to find genetic changes in individual leukemia cells to help doctors better understand and treat acute myeloid leukemia (AML).

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11146427

• Predicting which mouth lesions may turn into oral cancer

  This project uses noninvasive mouth samples plus AI and genetic markers to identify which premalignant mouth lesions are most likely to become oral cancer for people who have oral lesions.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11124924

• A new way to understand oral cancer risk

  This project aims to create a better tool to help doctors understand the risk of early-stage oral cancer returning or getting worse, so patients can receive the most effective treatment.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11103260

• Investigating how blood vessel function affects dementia in older adults

  This study is looking at how problems with blood vessels in the brain might lead to memory issues as we get older, like in Alzheimer's disease, and it’s using mice to find out how these blood flow problems develop, which could help us discover new ways to treat or prevent dementia.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11089456

• How pregnancy affects blood flow in the uterus and responds to low oxygen levels

  This study looks at how blood flow in the uterus changes during pregnancy, especially when there's less oxygen, like at high altitudes, to help us understand issues like preeclampsia and slow fetal growth, using pregnant sheep to learn more about how certain channels in the blood vessels work.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11075270

• Targeting specific signaling pathways in a type of leukemia

  This study is looking for better ways to treat people with a tough type of leukemia called Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) by testing new treatments that target specific proteins involved in the cancer's growth, hoping to help patients feel better with fewer side effects.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11030456

• Increasing diversity in biomedical Ph.D. programs at Loma Linda University

  This program is all about helping students from diverse backgrounds get the support and training they need to earn Ph.D. degrees in biomedical sciences, so they can have better chances in the job market and help make the field more inclusive.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11018467

• How maternal e-cigarette use affects brain development in offspring

  This study looks at how using e-cigarettes during pregnancy might affect the brain development of babies, especially in ways that could lead to conditions like ADHD and autism, and it aims to help understand the risks for moms and their little ones.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11015823

• Investigating how venous issues affect brain health after a type of stroke.

  This study is looking at how problems with blood flow in the veins can affect people who have had a serious type of stroke called aneurysmal subarachnoid hemorrhage, and it hopes to find new ways to help them recover better.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11012883

• Improving blood clot clearance after brain hemorrhage in infants

  This study is looking at ways to help preterm babies recover from blood clots that can happen after a type of brain bleed, with the hope of improving their brain health and reducing complications like fluid buildup in the brain.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10993610

• Understanding how low oxygen levels during pregnancy affect newborn lung health

  This study is looking at how not getting enough oxygen in the womb might cause high blood pressure in the lungs of newborns, and it aims to understand how a certain part of the lungs works to help with blood flow, which could lead to better treatments for babies who are affected.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10993588

• Understanding how a protein protects the brain after a specific type of stroke.

  This study is looking at how a protein called PEDF might help protect the brain after a serious type of stroke called aneurysmal subarachnoid hemorrhage, with the hope that it could lead to better treatments for people who have experienced this condition.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10989904

• Investigating the role of enolase in prostate cancer disparities among men of different ancestries

  This study is looking into why men of African descent are more likely to get prostate cancer than men of European descent, by exploring how their immune systems respond to a certain enzyme, with the hope of finding better treatment options for advanced prostate cancer.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10977476

• A tool to predict the risk of oral lesions turning into cancer

  This study is working on a new, easy-to-use tool that uses smart technology to help doctors spot early signs of mouth lesions that could turn into cancer, making it especially helpful for patients in places where healthcare is hard to get.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10973136

• Investigating the genetic factors of pain in head and neck cancer patients

  This study is looking at how changes in DNA might affect the pain felt by people with head and neck cancer, and by collecting tissue samples and pain information from patients, researchers hope to find new ways to help manage that pain better.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10913309

• Detecting gene changes in leukemia cells using advanced technology

  This study is looking at a new way to better understand and treat acute myeloid leukemia (AML) by using a special device to closely examine individual leukemia cells, which could help doctors choose the best treatment for patients and improve their chances of recovery.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10910039

• Understanding how the lungs communicate with the brain during development

  This study is looking at how the lungs and the brain work together in young sheep to see how this affects breathing and lung health, which could help us understand and treat breathing problems in newborns.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10908555

• Investigating the role of enolase in prostate cancer disparities among men of different ancestries

  This study is looking into why men of African descent are more likely to get prostate cancer than men of European descent, by exploring how their immune systems react to a certain enzyme, with the hope of finding new ways to treat prostate cancer.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10819531

• Investigating how blood cells protect the brain after delayed treatment for stroke

  This study is looking at how certain immune cells in the blood help the brain heal after a stroke caused by blocked blood vessels, especially when treatment is given later than usual, to find better ways to support recovery for stroke patients.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10806832

• How mitochondrial DNA affects blood vessel health during pregnancy

  This study is looking at how tiny pieces of DNA from the placenta might affect blood vessel health in pregnant women, especially those with high blood pressure issues like preeclampsia, to help find better ways to prevent and treat these problems.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10744771

• How high altitude affects blood vessel function in mothers and their babies during pregnancy

  This study looks at how living at high altitudes with low oxygen affects the blood vessels of pregnant women and their babies, aiming to find out how these changes can lead to complications like preeclampsia and growth issues, so we can better support pregnancies in those conditions.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10650166

• Using targeted nano-boron therapy to treat gliomas

  This study is testing a new way to treat aggressive brain tumors called gliomas by using a special nanodrug that helps deliver a targeted treatment directly to the cancer cells while protecting healthy tissue, making it a friendlier option for patients.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10600003

• Investigating the role of microRNA210 in brain inflammation after ischemic stroke

  This study is looking at how a tiny molecule called microRNA210 affects inflammation in the brain after a stroke, with the goal of finding new ways to help stroke patients recover better.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10579511

• Understanding social interaction challenges in youth with autism and schizophrenia

  This study is looking at how the brains of young people with autism and schizophrenia work when it comes to social interactions, hoping to find ways to help them improve their social skills and experiences.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10442538

Quick answers

How many clinical trials run by Loma Linda University are recruiting right now?

33, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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