Comparing muscle response monitoring using median and ulnar nerves during surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the muscle response to neuromuscular blockade at two different nerve sites in the arm: the ulnar nerve and the median nerve. Electromyography will be used to measure the depth of muscle relaxation during elective surgeries requiring general anesthesia. Participants will have electrodes placed on both arms to stimulate the ulnar nerve on one side and the median nerve on the other, allowing for a direct comparison of their responses. The study will help determine if the median nerve can provide comparable information to the ulnar nerve regarding neuromuscular transmission.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults 18 - 75 years of age who are able to provide consent
* Scheduled for elective surgery requiring muscle relaxation, in a supine position under general anesthesia, with an anticipated duration of at least 1.5 hours

Exclusion Criteria:

* Contraindication to rocuronium use
* Comorbidities that may prolong the duration of neuromuscular blockade or alter pharmacodynamics and/or pharmacokinetics, such as:
* Neuromuscular disease
* Expected or known difficult airway
* Rocuronium allergy
* BMI \< 18.5 or \> 40
* History of adhesive allergy
* Upper extremity weakness, limb deformity, or absence of all or part of an upper limb
* Patients undergoing surgical procedures requiring cardiopulmonary bypass

Where it's running

• Loma Linda University Troesch Medical Center
  Loma Linda, California, United States Recruiting

Study contacts

• Principal investigator: Michael Benggon, MD — Loma Linda University
• Study coordinator: Melissa D McCabe, MD, MSCR
• Email: mmccabe@llu.edu
• Phone: 909 558 4475

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.