Comparing Nifedipine and Labetalol for postpartum high blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized control trial aims to determine whether oral Nifedipine or oral Labetalol is more effective in managing high blood pressure in women after childbirth. High blood pressure is a common complication during and after pregnancy, and effective management is crucial to prevent serious health issues. Participants will receive either Nifedipine or Labetalol, with no experimental drugs involved. The study will assess the efficacy of these medications in controlling postpartum hypertension.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* Women who develop postpartum hypertension\* after delivery of the placenta or chronic hypertensive postpartum women who require medication for blood pressure control.

  * Postpartum hypertension requiring treatment are defined as systolic blood pressure greater than or equal to 140mmHg or diastolic blood pressure greater than or equal to 90mmHg on at least 2 occasions at least 4 hours apart, or systolic blood pressure greater than or equal to 160mmHg or diastolic blood pressure greater than 110mmHg sustained for more than 15 minutes.

Exclusion Criteria:

* History of moderate persistent asthma, coronary artery disease, heart failure, AV heart block, pulmonary edema
* Contraindication to either Nifedipine or Labetalol
* HR \<60 or \>110
* Native language other than English or Spanish

Where it's running

• Loma Linda University Health
  Loma Linda, California, United States Recruiting

Study contacts

• Study coordinator: Ashra Denise B Tugung, BSc
• Email: atugung@llu.edu
• Phone: 9096515580

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.