Using targeted nano-boron therapy to treat gliomas
Targeted nano-boron based boron neutron capture therapy for glioma treatment
This study is testing a new way to treat aggressive brain tumors called gliomas by using a special nanodrug that helps deliver a targeted treatment directly to the cancer cells while protecting healthy tissue, making it a friendlier option for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Loma Linda University NIH-funded |
| Lab location | 1 site (Loma Linda, UNITED STATES) |
| Project ID | NIH-10600003 on NIH RePORTER |
What this research studies
This research focuses on developing a new treatment for gliomas, which are aggressive brain tumors. It utilizes boron neutron capture therapy (BNCT), a noninvasive method that targets cancer cells while minimizing damage to surrounding healthy tissue. The approach involves creating a specialized nanodrug that can effectively cross the blood-brain barrier and deliver a high concentration of Boron-10 directly to glioma cells. By enhancing the delivery of this active drug, the research aims to improve treatment outcomes for patients with this challenging condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with gliomas who have not responded well to conventional treatments.
Not a fit: Patients with non-glioma brain tumors or those who are not eligible for BNCT may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve survival rates and quality of life for patients with gliomas.
How similar studies have performed: While BNCT has shown promise in other contexts, this specific approach using targeted nano-boron therapy is relatively novel and has not been extensively tested in clinical settings.
Where this research is happening
Loma Linda, UNITED STATES
- Loma Linda University — Loma Linda, United States (Active)
Researchers
- Principal investigator: Patil, Rameshwar Tukaram — Loma Linda University
- Study coordinator: Patil, Rameshwar Tukaram
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.