Improving blood clot clearance after brain hemorrhage in infants
Harnessing blood clot clearance mechanisms after germinal matrix hemorrhage
This study is looking at ways to help preterm babies recover from blood clots that can happen after a type of brain bleed, with the hope of improving their brain health and reducing complications like fluid buildup in the brain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Loma Linda University NIH-funded |
| Lab location | 1 site (Loma Linda, UNITED STATES) |
| Project ID | NIH-10993610 on NIH RePORTER |
What this research studies
This research investigates how to enhance the body's ability to clear blood clots that form after germinal matrix hemorrhage (GMH) in preterm infants. By focusing on the role of specific receptors and proteins involved in the inflammatory response and blood clot resolution, the study aims to improve neurological outcomes and reduce complications such as hydrocephalus. The approach includes examining the activation of receptors that promote the clearance of blood clots and the subsequent effects on brain health. The findings could lead to new therapeutic strategies for managing GMH.
Who could benefit from this research
Good fit: Ideal candidates for this research are preterm infants who have experienced germinal matrix hemorrhage.
Not a fit: Patients who are not preterm or who have not experienced germinal matrix hemorrhage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery and reduce long-term complications for infants affected by brain hemorrhage.
How similar studies have performed: Other research has shown promise in enhancing blood clot clearance mechanisms, suggesting that this approach could lead to meaningful advancements in treatment.
Where this research is happening
Loma Linda, UNITED STATES
- Loma Linda University — Loma Linda, United States (Active)
Researchers
- Principal investigator: Tang, Jiping — Loma Linda University
- Study coordinator: Tang, Jiping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.