Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Non-invasive treatment for piriformis muscle pain

Official title: Strain-Counterstrain Treatment of Piriformis Pain

Run by Loma Linda University · NCT05023005 · Data updated 2026-11-12

This study is testing a new non-invasive treatment for people with piriformis muscle pain to see if it helps reduce their pain compared to a sham treatment.

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Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment30 (estimated)
SponsorLoma Linda University
Academic / other
Locations1 site (Loma Linda, California)
StatusRecruiting
StartedSeptember 2026
Main results expectedSeptember 2027
Study endsSeptember 2027
Registry record updatedApril 24, 2026
Trial IDNCT05023005 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 65 with a tender point in the piriformis muscle.

Probably not a fit

Patients with significant hip mobility limitations, active cancer, or those receiving concurrent treatments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of strain-counterstrain treatment specifically targeting the piriformis muscle in patients experiencing pain. Participants will be divided into two groups: one receiving the actual treatment and the other receiving a sham treatment focused on the hamstring muscle. Pain levels will be assessed using the Oswestry Disability Index Questionnaire and the Visual Analog Scale before and after each of the two treatment sessions, which are spaced 1-2 weeks apart. An algometer will also be utilized to measure changes in pain pressure threshold pre and post-treatment.

Why it matters

Potential benefit: If successful, this treatment could provide a non-invasive option for patients suffering from piriformis-related pain.

How similar studies have gone: While the specific approach of strain-counterstrain for piriformis pain is less common, similar non-invasive treatments have shown promise in managing musculoskeletal pain.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 to 65 years of age
* Tender point (or trigger point) in piriformis muscle determined by physical exam

Exclusion criteria:

* Less than 45 degrees of active hip flexion, less than 5 degrees of active hip internal rotation or less than 30 degrees of active hip external rotation, on side of affected piriformis
* Unable to lay prone
* Non-English speaker
* Inability to attend 2 sessions within the same month
* Active cancer
* Pregnant
* Diagnosis of lumbar radiculopathy
* Greater than grade 1 lumbar spondylolisthesis
* Presence of lumbar region Pars Defect
* Receiving massage, acupuncture, chiropractic treatments, osteopathic treatments during study period.

Where it's running

  • Loma Linda University Health
    Loma Linda, California, United States
    Recruiting

Study contacts

  • Principal investigator: Mickey Lui — Loma Linda University Health
  • Study coordinator: Roya Vahdatinia, DO
  • Email: rvahdatinia@llu.edu
  • Phone: 9095586202

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.