Comparing saline and chlorhexidine for wound irrigation after cesarean delivery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial compares the effects of normal saline and a low concentration of Chlorhexidine Gluconate (Irrisept) for wound irrigation in patients who have undergone cesarean delivery. It is an open-label, randomized controlled trial designed to assess postoperative wound healing outcomes. The study will enroll participants who meet specific eligibility criteria, including age and certain medical complications, and will be conducted at Loma Linda University Children's Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 or older
* Singleton pregnancy
* Planned cesarean delivery at gestational age 37 weeks or later at Loma Linda University Children's Hospital
* Planned post-operative follow up with Loma Linda OBGYN
* Speak English or Spanish
* At least one of the following medical complications: Obesity BMI\>= 30kg/m2, Diabetes, Spontaneous rupture of membranes, Intraamniotic infection

Exclusion Criteria:

* Emergency cesarean delivery

Where it's running

• Loma Linda University
  Loma Linda, California, United States Recruiting

Study contacts

• Principal investigator: Ruofan Yao, MD, MPH — Loma Linda University
• Study coordinator: Nikia Gray-Hutto, AS
• Email: nhutto@llu.edu
• Phone: 9095584000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing single-layer and double-layer closure techniques in cesarean sections

  This study is testing whether closing the uterus with one layer or two layers after a cesarean section affects the amount and length of spotting women experience afterward.

  Recruiting Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Milan, Mi · NCT06308172

• Effects of massage and exercises on cesarean scar and recovery

  This study tests whether direct scar massage or indirect massage plus exercise helps people recover after a cesarean birth and reduces scar-related pain.

  Recruiting Concordia University, Montreal · Montreal, Quebec · NCT07897253

• Reflexology and hand massage after cesarean section

  This study tests whether reflexology hand massage or stroking hand massage can reduce anxiety and increase satisfaction, and how they affect heart/blood pressure after cesarean delivery.

  Recruiting Dokuz Eylul University · Izmir · NCT07880587

• Health education to see if primigravida women choose vaginal delivery more often

  A health education program is being tested to see if it helps first-time pregnant women in choosing vaginal delivery over unnecessary cesareans.

  Recruiting Assiut University · Asyut, Asyut Governorate · NCT07810751

• Reducing Chronic Pain After Cesarean Delivery

  A single-session pain-relief class called Empowered Relief is tested alongside standard postpartum care to see if it helps women who have ongoing pain after cesarean delivery.

  Recruiting Stanford University · Palo Alto, California · NCT07799883

• Enhanced Recovery Adherence and Recovery Quality After Cesarean Delivery

  This study tests whether following enhanced recovery after cesarean delivery protocols is linked with better recovery quality in women having a planned cesarean with spinal anesthesia.

  Recruiting Bursa City Hospital · Bursa, Nilüfer · NCT07790471

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.