Reducing radiation exposure during sacral neuromodulation lead placement

Reduction in Fluoroscopy Radiation Exposure During Lead Implantation for Sacral Neuromodulation: A Randomized Prospective Study

NA · Loma Linda University · NCT04527445

This study tests if using lower radiation settings during sacral neuromodulation lead placement can help keep patients with overactive bladder safe while still getting the procedure done correctly.

Quick facts

PhaseNA
Study typeInterventional
Enrollment44 (estimated)
Ages18 Years to 89 Years
SexAll
SponsorLoma Linda University (other)
Drugs / interventionsradiation
Locations1 site (Loma Linda, California)
Trial IDNCT04527445 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of reduced radiation fluoroscopy settings compared to conventional fluoroscopy during the lead placement for sacral neuromodulation in patients with overactive bladder. Patients scheduled for this procedure will be randomized into two groups: one receiving the experimental reduced radiation settings and the other receiving standard fluoroscopic settings. The primary focus is to compare the radiation exposure between these two groups while ensuring optimal lead placement by the surgeon. The study aims to enhance patient safety by minimizing radiation exposure during this common procedure.

Who should consider this trial

Good fit: Ideal candidates are patients with overactive bladder who are scheduled for lead implantation for sacral neuromodulation.

Not a fit: Patients with neurogenic bladder, a BMI over 40, or peripheral neuropathy may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce radiation exposure for patients undergoing sacral neuromodulation, enhancing their safety during the procedure.

How similar studies have performed: While the approach of reducing radiation exposure in fluoroscopy is being explored, this specific application in sacral neuromodulation is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing lead implantation for sacral neuromodulation that have overactive bladder as defined by urinary urgency, frequency, nocturia with or without urgency incontinence.

Exclusion Criteria:

* neurogenic bladder, BMI \>40, or peripheral neuropathy.

Where this trial is running

Loma Linda, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Radiation Exposure, Overactive Bladder, Urge Incontinence, Urgency-frequency Syndrome, Sacral Neuromodulation, Fluoroscopy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.