Understanding how the lungs communicate with the brain during development
Unravelling lung interoception and its functional consequence in the developing ovine lung
['FUNDING_R01'] · LOMA LINDA UNIVERSITY · NIH-10908555
This study is looking at how the lungs and the brain work together in young sheep to see how this affects breathing and lung health, which could help us understand and treat breathing problems in newborns.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LOMA LINDA UNIVERSITY (nih funded) |
| Locations | 1 site (Loma Linda, UNITED STATES) |
| Trial ID | NIH-10908555 on ClinicalTrials.gov |
What this research studies
This research investigates the connection between the lungs and the central nervous system (CNS) in developing sheep to understand how this communication affects lung function and development. By using advanced techniques, the researchers aim to map the neural pathways that carry important information about lung health and responses to environmental changes. The study focuses on how these pathways develop and their role in maintaining proper breathing and immune responses in newborns. The findings could provide insights into lung development and potential treatments for respiratory issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns and young children, particularly those with respiratory issues or those born via cesarean delivery.
Not a fit: Patients with fully developed lungs and no history of respiratory problems may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of respiratory conditions in newborns and children.
How similar studies have performed: While the specific approach of this research is novel, similar studies have shown success in understanding lung development and its implications for respiratory health.
Where this research is happening
Loma Linda, UNITED STATES
- LOMA LINDA UNIVERSITY — Loma Linda, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BLOOD, ARLIN B — LOMA LINDA UNIVERSITY
- Study coordinator: BLOOD, ARLIN B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.