Investigating the genetic factors of pain in head and neck cancer patients

Who could benefit from this research

What this research studies

This research focuses on understanding how changes in DNA methylation affect pain experienced by patients with head and neck squamous cell carcinoma (HNSCC). By enrolling patients and assessing their pain levels through validated questionnaires, researchers will collect cancer tissue samples to analyze the genetic markers associated with severe pain. The goal is to identify specific genes that are hypermethylated in these patients, which could lead to new treatment strategies using hypomethylating agents. This approach aims to bridge the gap between basic science and clinical application, ultimately improving pain management for HNSCC patients.

Why it matters

Where this research is happening

• Loma Linda University
  Loma Linda, United States Active

Researchers

• Principal investigator: Viet, Chi T. — Loma Linda University
• Study coordinator: Viet, Chi T.

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.