Condition

HIV-1-infection clinical trials and research

As of November 12, 2026, Find a Trial lists 41 HIV-1-infection clinical trials that are recruiting, at sites in 31 countries (most in United States (22), South Africa (4), Italy (3)). By phase: Phase 2 (7), Phase 1 (6), Phase 4 (6), Phase 3 (4). The most active sponsors are Gilead Sciences (7), University of California, San Francisco (2), International Maternal Pediatric Adolescent AIDS Clinical Trials Group (2). There are also 40 NIH-funded research projects on HIV-1-infection, with $30.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.

Newest HIV-1-infection clinical trials

StudyPhaseWhereStatusRegistered
Weekly long-acting HIV-1 meds switch for people with undetectable virus Phase 2 Ft. Pierce, Florida and 1 other locations Recruiting Sep 25, 2026
HIV in Hong Kong: patterns, transmission, and burden over time — North Point Recruiting Jul 24, 2026
GS-0415 safety and PK in people with HIV on ART Phase 1 Los Angeles, California and 15 other locations Recruiting Jul 22, 2026
Gilead study of GS-3242 with Lenacapavir for people starting HIV treatment compared with Biktarvy Phase 2/3 Torrance, California and 20 other locations Recruiting Jul 16, 2026
RNA-based vaccine BNT168 safety and immune response in adults with or without HIV Phase 1 Houston, Texas and 3 other locations Recruiting Jul 13, 2026
Long-acting LEN/TAB/ZAB regimen vs daily HIV meds in adults with suppressed HIV-1 Phase 3 Berkeley, Michigan and 1 other locations Recruiting Jul 6, 2026
Switch to GS-3242 plus Lenacapavir vs Biktarvy in virologically suppressed people with HIV-1 Phase 2 Phoenix, Arizona and 58 other locations Recruiting Jun 12, 2026
How HIV Treatment Changes Affect Hidden Drug Resistance — Hong Kong, Hong Kong Recruiting Jun 12, 2026
Long-acting cabotegravir and rilpivirine in pregnancy Phase 4 La Jolla, California and 9 other locations Recruiting Jun 10, 2026
Dolutegravir/Lamivudine in treatment-naïve pregnant women Phase 4 Ciudad Autónoma de Buenos Aires, Buenos Aires and 9 other locations Recruiting Jun 1, 2026

All recruiting trials (41)

NIH-funded research (40)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

Related topics

HIVHIV 2 InfectionAbdominal ObesityAgingAlcohol DrinkingBreastfeedingCoronary Microvascular DysfunctionDepressionFrailtyHIV (Human Immunodeficiency Virus)HIV InfectionsInfectious DiseaseMetabolic DiseaseObesity

Quick answers

How many HIV-1-infection clinical trials are recruiting right now?

41, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 31 countries. The most sites are in United States (22 trials), South Africa (4 trials), Italy (3 trials), Germany (3 trials), Argentina (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 1: 6, Phase 4: 6, Phase 3: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →

Last reviewed 2026-11-12 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.