Investigating lung cancer risks in people with HIV-1 in Uganda and Tanzania
Official title: Characterization of the clinical epidemiology of lung cancer and relationship to HIV-1 infection in Uganda and Tanzania
Funded at Case Western Reserve University · NIH-10904978 · Data updated 2026-11-12
This study is looking at how being infected with HIV-1 might increase the chances of getting lung cancer, especially in Uganda and Tanzania, and it wants to find out what other factors, like smoking and the environment, play a role so that we can come up with better ways to prevent and catch lung cancer early for people living with HIV-1.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 21, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $250,947 |
| NIH project number | 5U54CA254566-05 |
| Project ID | NIH-10904978 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV-1 in Uganda and Tanzania, particularly those at risk for lung cancer.
✕Less likely to help
Patients who do not have HIV-1 or those who are not at risk for lung cancer may not benefit from this research.
What this research studies
This research focuses on understanding how HIV-1 infection affects the risk of developing lung cancer, particularly in Uganda and Tanzania. It aims to identify various risk factors such as environmental influences, smoking habits, and geographical factors that may contribute to lung cancer in HIV-1 infected individuals. By gathering this information, the research seeks to create effective prevention strategies and screening programs tailored for those living with HIV-1, ultimately aiming to detect lung cancer earlier and improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved screening and prevention strategies for lung cancer in HIV-1 infected individuals, potentially saving lives.
How similar studies have gone: Previous studies have indicated a link between HIV-1 infection and increased cancer risk, suggesting that this research builds on established findings rather than exploring entirely novel territory.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Kasasa, Simon — Case Western Reserve University
- Study coordinator: Kasasa, Simon
Related research
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Digital health strategies to expand lung cancer screening in safety-net clinics
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.