Effects of certain molecules on brain cell growth after methamphetamine use and HIV infection
Impact of miRNAs on adult neurogenesis following exposure to methamphetamine and HIV-1 Infection
['FUNDING_R21'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-11057620
This study is looking at how methamphetamine and HIV might affect the growth of new brain cells in adults, especially by exploring the role of certain molecules that help move brain cells around, with the hope of finding new ways to help people with HIV who also use meth.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (CORAL GABLES, UNITED STATES) |
| Trial ID | NIH-11057620 on ClinicalTrials.gov |
What this research studies
This research investigates how exposure to methamphetamine and HIV affects the growth of new brain cells in adults. It focuses on the role of specific molecules called microRNAs in this process, particularly how they influence the movement of neural progenitor cells in the brain. By studying these interactions, the research aims to uncover potential mechanisms that could lead to new treatments for neurocognitive issues faced by individuals with HIV who also use methamphetamine.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults living with HIV who have a history of methamphetamine use.
Not a fit: Patients who do not have HIV or a history of methamphetamine use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies to improve brain health and cognitive function in HIV-positive individuals who have a history of substance abuse.
How similar studies have performed: Previous research has shown promising results in understanding the effects of substances on neurogenesis, but this specific approach focusing on microRNAs in the context of HIV and methamphetamine is relatively novel.
Where this research is happening
CORAL GABLES, UNITED STATES
- UNIVERSITY OF MIAMI SCHOOL OF MEDICINE — CORAL GABLES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARK, MIN SEON — UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- Study coordinator: PARK, MIN SEON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus