Condition

Infectious Disease clinical trials and research

• 15Clinical trials
• 93NIH research projects
• 32Countries

Newest Infectious Disease clinical trials

All recruiting trials (15)

• International collaboration to collect information on adults hospitalized with acute infections

  Researchers will collect health information and biological samples from adults hospitalized with acute infections to see how these infections start, progress, and respond to care.

  Recruiting at 55 sites University of Minnesota · Tucson, Arizona and 55 other locations · NCT07069400

• Pharmacogenomics to improve voriconazole dosing for fungal infections

  This trial will test whether using a patient's CYP2C19 genotype with Bayesian dosing software helps get voriconazole levels into the therapeutic range by Day 8 for people with fungal infections, including those with blood cancers.

  Recruiting at 7 sites Phase 2 The University of Queensland · Seattle, Washington and 6 other locations · NCT06510699

• Survey to assess eligibility for infectious disease clinical trials

  This study is trying to find out if people are eligible to join clinical trials for infectious diseases like HIV and vaccines by having them fill out a survey about their health and background.

  Recruiting Brooklyn Clinical Research · Brooklyn, New York · NCT06492187

• L-citrulline to reduce complications in hospitalized young children with fever

  This trial will test whether giving L-citrulline versus placebo to hospitalized children aged 1 month to under 5 years who have a moderate-to-high bedside sTREM-1 risk result can reduce death and serious complications.

  Recruiting at 2 sites Barcelona Institute for Global Health · Harar and 1 other locations · NCT06426147

• Rapid suPAR blood test to help triage febrile young children

  This study will test whether adding a quick suPAR point-of-care blood test to standard IMCI triage helps health workers better spot children aged 2–59 months with fever who need admission or referral.

  Recruiting at 2 sites Barcelona Institute for Global Health · Lambaréné, Moyen-Ogooué Province and 1 other locations · NCT06422338

• Investigating genetic factors in severe infections

  This study is trying to find out if certain genes make some people more likely to get severe infections than others by looking at patients with rare and serious infections.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris, Île-de-France Region · NCT06102070

• Evaluating high doses of favipiravir in healthy volunteers

  This study is testing how well healthy volunteers can tolerate high doses of favipiravir over two weeks to learn more about its safety and how the body processes it.

  Recruiting Phase 1 Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT06024421

• Using antibiotics to treat delirium in older adults without clear urinary infections

  This study tests whether giving antibiotics can help older adults with delirium feel better, even if they don't have a clear urinary infection.

  Recruiting at 2 sites Mount Sinai Hospital, Canada · Chicago, Illinois and 6 other locations · NCT06004739

• Treatment for murine and scrub typhus infections

  This study is testing if the antibiotics doxycycline and azithromycin can effectively treat adults with murine and scrub typhus infections while they are hospitalized.

  Recruiting at 2 sites Phase 2/3 Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit · Vientiane, Vientaine and 1 other locations · NCT05972772

• Characterizing patients treated at internal medicine clinics

  This study looks at patients with serious health issues treated in internal medicine clinics to see how their different conditions affect their care and to find better ways to diagnose and treat them.

  Recruiting at 2 sites IRCCS San Raffaele · Milan and 1 other locations · NCT05780099

• Metabolic and infectious diseases in La Réunion

  Researchers are testing how common metabolic and infectious diseases are in La Réunion and what factors like microbiota and genetics might influence them, by examining 2,000 adults over two years.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · La Réunion, Saint-Pierre · NCT05400824

• Registry for monitoring CytoSorb device use in critically ill patients

  This study is collecting information on how the CytoSorb device helps critically ill patients to improve care for conditions like septic shock and acute respiratory distress syndrome.

  Recruiting at 24 sites CytoSorbents, Inc · Klagenfurt and 27 other locations · NCT05146336

• Stopping antibiotics for viral respiratory infections

  This study is testing if hospitalized adults with viral respiratory infections can safely stop taking antibiotics without affecting their recovery compared to those who keep taking them.

  Recruiting at 8 sites Phase 4 University Hospital, Akershus · Bergen and 11 other locations · NCT05045612

• Dengue vaccination strategy for children in the French Caribbean

  This study is trying to see how many children in Martinique and Guadeloupe have been exposed to dengue and whether parents are open to giving them the Dengvaxia® vaccine.

  Recruiting University Hospital Center of Martinique · Fort-de-France · NCT04839757

• Collection and distribution of biospecimens for research purposes

  This study is trying to see how collecting samples from healthy people and those with medical conditions can help researchers find new ways to diagnose and treat diseases.

  Recruiting iSpecimen Inc · Huntsville, Alabama and 1 other locations · NCT03848962

NIH-funded research (newest 40 of 93)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Latin American Center for Emerging Infectious Disease Surveillance and Readiness

  A regional collaboration in Peru and neighboring countries aims to strengthen early warning and monitoring for viruses that could jump from animals to people, helping communities prepare for outbreaks.

  NIH research University of California at Davis · Davis, United States · NIH-11601583

• Center in Latin America to monitor emerging infectious diseases

  A U01 grant supporting a collaboration between Peruvian and U.S. researchers to improve early detection and surveillance of regionally relevant viruses that could affect people, animals, and crops in Peru and neighboring areas.

  NIH research University of California at Davis · Davis, United States · NIH-11601582

• Acanthamoeba as a modern model parasite to study infectious disease biology and mitochondria

  A five-year project will define the mitochondrial proteins and pathways of Acanthamoeba castellanii to advance infectious disease biology and parasite metabolism.

  NIH research Morgridge Institute for Research, INC. · Madison, United States · NIH-11579896

• IDEAL project helps predict vaccine response, infections, and asthma in early childhood

  A Child-focused program will collect and share saliva, blood, and tissue samples from diverse infants to find biological patterns that predict how vaccines work, how respiratory infections occur, and who develops asthma.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11497516

• Understanding how early-life immune development affects vaccine responses and asthma risk in children

  This project uses lab-grown human immune cells from infants and young children to explore why some kids respond poorly to vaccines and are more prone to respiratory infections and asthma.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11496694

• Multi-omic endotypes of vaccine response, respiratory infections, and asthma in children

  A parent-friendly look at how early-life immune development shapes how kids respond to vaccines and stay free from lung infections and asthma, using advanced biological profiling.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11496691

• IDEAL: How early-life immune development shapes vaccine responses and asthma risk

  A child-focused project that looks at how the developing immune system in early life affects vaccine responses, respiratory infections, and asthma.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11496688

• IDEAL: How the microbiome shapes vaccine response, infections, and asthma in kids

  This project uses data from thousands of children to understand how the microbiome affects vaccines, respiratory infections, and asthma.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11496683

• IDEAL: How babies’ immune systems shape vaccines, infections and asthma

  A large NIH project will build a cloud-based system to map how early-life immune development relates to vaccine responses, respiratory infections, and asthma in children.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11496671

• IDEAL: How immune systems develop in early life shape vaccines, infections, and asthma

  A patient-friendly overview of a program at Boston Children’s Hospital exploring how early immune development affects vaccine responses, respiratory infections, and asthma in children.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11496670

• Reproductive and Child Health in Times of Infectious Crises

  This grant follows women’s reproductive lives in a country hit by infectious disease crises to see how shocks affect pregnancy and fertility over time.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11474414

• Center to speed up AI-powered infectious disease research

  A Cornell-led center is using artificial intelligence to connect weather, ecosystems, and human health data to build usable models that predict infectious disease risks after extreme weather events.

  NIH research Cornell University · Ithaca, United States · NIH-11421473

• Center for Transformative Infectious Disease Research (CTIDR) at Cornell

  A research center at Cornell aims to create predictive health tools and preventative measures for infectious diseases influenced by weather, by engaging communities and studying how humans, animals, and the environment interact.

  NIH research Cornell University · Ithaca, United States · NIH-11421469

• Center for Transformative Infectious Disease Research: A new approach to preventing vector-borne diseases

  A community-focused project from Cornell aims to understand how weather, human behavior, and animals influence the spread of diseases carried by mosquitoes and other vectors, with the goal of guiding practical prevention measures.

  NIH research Cornell University · Ithaca, United States · NIH-11421468

• How Weather and Seasons Change Bat Diseases and Protect People

  This project studies how extreme weather and seasonal changes influence bat diseases to help prevent spillover to people.

  NIH research Cornell University · Ithaca, United States · NIH-11421466

• Center for Transformative Infectious Disease Research

  A Cornell center is building community-based, data-driven ways to predict and prevent infectious disease outbreaks.

  NIH research Cornell University · Ithaca, United States · NIH-11421464

• Center for Transformative Infectious Disease Research (CTIDR)

  A research center in Cornell aims to understand how weather, animals, people, and pathogens come together to cause infectious disease outbreaks, with plans to build better predictive models and prevention tools.

  NIH research Cornell University · Ithaca, United States · NIH-11421463

• New ways to model how people behave and how infections spread

  A new project at UC Berkeley will build models that connect how people act and how diseases spread, to better understand outbreaks.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11400038

• How Laws and Public Opinion Shape People’s Use of HIV Testing and Public Health Measures

  This project looks at how people’s beliefs about laws and government requirements affect their willingness to get HIV testing and follow public health guidance.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11398191

• Improve infectious disease forecasts by understanding how errors grow

  A project to understand why predicting infectious disease outbreaks becomes less accurate over time and to make those forecasts more reliable for planning care.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11392219

• Infectious disease core for xenotransplantation safety

  A central lab at a major hospital will monitor infectious risks in xenotransplantation using advanced sequencing to protect patients receiving animal organs or tissues.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11391067

• Observational tools to understand how infectious diseases spread and respond to interventions

  A researcher team at Brown University is building advanced real-world methods to measure how interventions like vaccines or public health measures actually affect the spread of infections in communities.

  NIH research Brown University · Providence, United States · NIH-11389361

• Elucidating chemical signals that shape multicellularity and infectious disease transmission

  Researchers are studying how chemicals used for cell communication in microbes influence the way diseases spread and how multicellular organisms develop.

  NIH research Trustees of Indiana University · Bloomington, United States · NIH-11384348

• How disease spreads in households can be tracked with smarter statistics

  A new research project will improve statistical methods to study how infectious diseases pass between people in households and close contacts, helping public health teams respond more effectively.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11378525

• EpiMoRPH: tools to design location-specific plans to control infectious disease

  This project creates a computer toolkit to help local public health teams choose location-focused ways to reduce spread of COVID-19 and other infectious diseases.

  NIH research Northern Arizona University · Flagstaff, United States · NIH-11374804

• SSCIMA: Improving local disease models by combining where people live and how they move

  A national research grant is funding new methods to model infectious disease spread at the level of neighborhoods by using local demographics and movement patterns.

  NIH research Northern Arizona University · Flagstaff, United States · NIH-11368491

• Collection and management of biological samples for maternal and pediatric infectious diseases

  This study is gathering biological samples from mothers and children to help researchers learn more about infectious diseases that affect them, with the hope of improving treatments and care for patients in the future.

  NIH research Fisher Bioservices, INC. · Rockville, United States · NIH-11354873

• Enhancing deer mice as a disease research model for Lyme disease, hantavirus, and SARS-CoV-2

  This grant funds improving a deer mouse research community resource to better study infectious diseases that affect people.

  NIH research University of South Carolina at Columbia · Columbia, United States · NIH-11335694

• Next-Generation Infectious Disease Diagnostics using Multiplexed Digital PCR

  A new diagnostic approach aims to detect and quantify many pathogens at once, helping doctors choose the right treatment for infections of the lungs, brain, blood, and immune-related conditions.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11333839

• Real-time forecasting and inference tools for infectious disease outbreaks

  Aims to improve real-time forecasts of infectious disease outbreaks to help communities respond quickly and effectively.

  NIH research University of Massachusetts Amherst · Hadley, United States · NIH-11329484

• Portable plasmonic sensors for quick virus detection

  This project is building portable, highly sensitive sensors that can quickly detect viral genetic markers, including SARS‑CoV‑2 and its variants, at the point of care.

  NIH research University of Cincinnati · Cincinnati, United States · NIH-11321701

• Measuring how vaccines protect people and communities

  This project creates better ways to show how vaccines protect vaccinated people and also reduce disease spread to others.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11296240

• Understanding who is at risk for Valley Fever and why

  This project looks at how immunity in the population affects the spread of Valley Fever and how we might better protect people in areas like the Southwest.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11295039

• Real-time models to send medical help and supplies to underserved communities during outbreaks

  This project builds real-time models to help mobile clinics and health teams get testing, treatments, and supplies to people in underserved communities during infectious outbreaks like COVID-19 and HIV.

  NIH research Clemson University · Clemson, United States · NIH-11240299

• Thailand HIV/AIDS Clinical Unit in Chiang Mai and Bangkok

  This program runs studies testing new HIV treatments, prevention methods, and vaccines for people living with or at risk for HIV in Thailand.

  NIH research Chiang Mai University · Chiang Mai, Thailand · NIH-11238908

• Community care linking people leaving jail to HIV and opioid treatment

  This project compares two ways to connect people leaving jail or prison who use opioids or are at risk for HIV to local HIV prevention/treatment and addiction services.

  NIH research Yale University · New Haven, United States · NIH-11238326

• Improving the use of deer mice to study infectious diseases

  This study is working to make deer mice better helpers for scientists studying diseases like COVID-19 and Lyme disease, so they can breed more of these mice, create better tools for research, and share important information, ultimately helping to improve our understanding and treatment of these illnesses that affect pe

  NIH research University of South Carolina at Columbia · Columbia, United States · NIH-11198321

• How human movement and behavior shape infectious disease spread

  This project builds computer models that link people's contacts, movement, and protective actions to how infections spread so communities can better target prevention.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11196221

• How weather and community practices affect mosquito- and tick-borne infections

  This project looks at how changes in weather and local behaviors affect the spread of infections carried by mosquitoes and ticks in communities at risk.

  NIH research Cornell University · Ithaca, United States · NIH-11193940

• Preventing infectious diseases that jump from animals to people

  This project looks at how extreme weather and seasonal changes affect when and where bat infections can spread to people so we can better prevent new outbreaks.

  NIH research Cornell University · Ithaca, United States · NIH-11193935

Related topics

Quick answers

How many Infectious Disease clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 32 countries. The most sites are in United States (5 trials), France (4 trials), Italy (2 trials), Mozambique (2 trials), Australia (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 2/3: 1, Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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