Registry of HIV-1 Patients with Drug Resistance

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The PRESTIGIO Registry is an observational, multicenter initiative that tracks patients with HIV-1 infection who have documented resistance to multiple classes of antiretroviral drugs. This registry aims to evaluate the long-term effectiveness of various antiretroviral regimens, monitor the evolution of drug resistance, and assess clinical outcomes such as mortality and the incidence of opportunistic infections. Data collection will include clinical, laboratory, and treatment characteristics, with participation from infectious disease centers across Italy. The study will continue for at least three years following ethical approval from participating centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* subjects with HIV-1 infection;
* age \>14 years;
* documented resistance to the 4 classes of antiretroviral drugs (NRTI, NNRTI, PI, INI), defined as resistance (at least intermediate) to at least one of the drugs in each class according to the Stanford algorithm. Resistance can be documented either at the time of inclusion in the study or previously documented throughout the patient's therapeutic history.

Exclusion Criteria:

* none

Where it's running

• Ospedale San Raffaele
  Milan, Mi, Italy Recruiting

Study contacts

• Principal investigator: Antonella Castagna — san raffaele
• Study coordinator: Antonella Castagna
• Email: castagna.antonella1@hsr.it
• Phone: 0226437934

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.