Condition

Bariatric Surgery clinical trials and research

• 60Clinical trials
• 50NIH research projects
• 2New in 30 days
• 23Countries

Newest Bariatric Surgery clinical trials

All recruiting trials (60)

• 15-year outcomes after sleeve gastrectomy in France

  This study looks at how people who had sleeve gastrectomy have fared over 15 years to see long-term weight changes and health effects.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07883018

• Mother and baby health after bariatric surgery in pregnancy

  This study follows pregnant women who have had bariatric surgery and those who have not to see how nutrition, pregnancy health, and baby outcomes compare.

  Recruiting at 3 sites Helse Nord-Trøndelag HF · Ålesund, Møre og Romsdal and 2 other locations · NCT07877233

• Understanding glucagon and sugar metabolism after meals in people with and without PBH after weight-loss surgery

  This study tests how glucagon and post-meal glucose handling differ between people who have post-bariatric surgery hypoglycemia and those who don’t.

  Recruiting at 2 sites Phase 4 Joslin Diabetes Center · Birmingham, Alabama and 1 other locations · NCT07818707

• Collagen Supplements After Sleeve Gastrectomy

  This observational study looks to see if taking collagen-containing supplements after sleeve gastrectomy affects muscle mass, body composition, and body image in adults who had bariatric surgery.

  Recruiting Mudanya University · Bursa, Yıldırım · NCT07809152

• Postoperative nausea, vomiting and pain after bariatric surgery in Sweden

  This study looks at how often people have nausea, vomiting, and pain after bariatric surgery in Sweden and whether anesthesia type or regional blocks affect those outcomes.

  Recruiting at 2 sites Umeå University · Sundsvall and 1 other locations · NCT07797374

• Hormonal changes after two bariatric surgeries in super-obese people

  This study tests whether sleeve gastrectomy with duodenojejunal bypass leads to different hormone responses and less post-meal hypoglycemia than Roux-en-Y gastric bypass in people with extreme obesity.

  Recruiting Chulalongkorn University · Pathum Wan, Bangkok · NCT07747779

• Sarcopenia After Bariatric Surgery: Changes in Muscle and Function

  This study tests how bariatric surgery affects muscle mass, strength, and physical performance over time in adults undergoing the procedure.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Istanbul, KÜÇÜKÇEKMECE · NCT07717333

• Dramatherapy Added to Physical Activity for Obesity Care

  This trial tests whether adding dramatherapy to a standard adapted physical activity program helps adults with obesity in bariatric or medical care improve psychosocial well‑being and weight-related outcomes.

  Recruiting Universite du Littoral Cote d'Opale · Blendecques, Hauts-de-France · NCT07685483

• Time-restricted eating after bariatric surgery

  This study tests whether a 16:8 eating window helps adults with obesity, including those who have had bariatric surgery, see weight or metabolic improvements.

  Recruiting at 2 sites Medipol University · Bursa, Lütfen Seçiniz. and 1 other locations · NCT07672821

• Transcutaneous Nerve Stimulation to Help Breathing After Bariatric Surgery

  A randomized trial tests whether a skin-placed nerve stimulator can reduce diaphragmatic dysfunction after bariatric surgery in people with obesity.

  Recruiting Cairo University · Cairo and 1 other locations · NCT07569705

• Suzetrigine added to multimodal opioid-sparing pain care for heart and weight-loss surgery

  This trial will test whether adding suzetrigine to standard multimodal pain care lowers opioid use and pain after bariatric or open-heart (sternotomy) surgery in adults.

  Recruiting Phase 3 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07539623

• Digital follow-up and nursing education after bariatric surgery

  This trial tests whether adding a digital follow-up system plus structured nursing education helps people who have had bariatric surgery improve quality of life, BMI, and activity levels.

  Recruiting Okan University · Istanbul, ÜSKÜDAR · NCT07457034

• Flow-controlled versus volume-controlled ventilation during bariatric surgery

  This trial will see if flow-controlled ventilation or volume-controlled ventilation gives better oxygen levels and lower airway pressures during bariatric surgery in adults with obesity.

  Recruiting Ankara Etlik City Hospital · Ankara · NCT07430111

• Scalp hair chemical changes in people with severe obesity and after bariatric surgery

  This project will see if chemicals trapped in scalp hair change with body weight and can signal hair thinning or muscle loss in adults having bariatric surgery.

  Recruiting Singapore General Hospital · Singapore · NCT07368842

• Magnetic anastomosis to create a partial jejuno-ileal diversion

  This will try a new endoscopic magnetic device to create a partial jejuno‑ileal diversion in adults with obesity and type 2 diabetes to help improve blood sugar and weight control.

  Recruiting iIDEAS Group Holdings Limited · Ahmedabad, Gujarat · NCT07350967

• IV lidocaine versus IV dexmedetomidine for pain control during sleeve gastrectomy

  It tests whether an IV infusion of lidocaine or dexmedetomidine given during laparoscopic sleeve gastrectomy helps reduce early postoperative pain and the need for opioid pain medicines in adults aged 20–50 with BMI 35–50.

  Recruiting Alexandria University · Alexandria · NCT07327905

• Supervised exercise after bariatric surgery to protect muscle and bone

  This program tests whether supervised exercise after gastric bypass or sleeve surgery helps preserve muscle mass and bone density in adults.

  Recruiting at 2 sites Hospitales Universitarios Virgen del Rocío · Seville, Sevilla and 1 other locations · NCT07324447

• Protein-collagen supplementation plus resistance exercise to prevent muscle loss after bariatric surgery

  This trial will test whether adding collagen to standard whey protein and doing resistance exercise helps people who have bariatric surgery keep muscle and change fat mass.

  Recruiting Medipol University · Istanbul, Fatih · NCT07303543

• Respiratory muscle training for people after bariatric surgery

  This study will test whether using an inspiratory muscle training device, alone or together with supervised therapeutic exercise, helps people who recently had bariatric surgery breathe better, sleep better, and improve exercise and metabolic measures.

  Recruiting University Ramon Llull · Quito, Pichincha · NCT07289958

• Digestion and gut function after bariatric surgery

  This project will test how digestion — including enzymes, bile acids, pH, and transit time — works in adults with obesity and in people at least one year after Roux‑en‑Y or sleeve gastrectomy by collecting intestinal samples and using a swallowable sensor capsule.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07286968

• A gut-microbiota–friendly diet after bariatric surgery to help eating habits and taste

  This tests whether a diet designed to increase gut microbiota diversity helps adults who have had sleeve gastrectomy or Roux-en-Y gastric bypass keep weight off, change food preferences and taste/smell, and improve gut-related health compared with standard nutrition counseling.

  Recruiting Hospices Civils de Lyon · Lyon and 2 other locations · NCT07268508

• Preoperative IV ferric derisomaltose to prevent anemia and improve quality of life in obese patients having bariatric surgery

  This trial tests whether a single preoperative IV ferric derisomaltose dose, compared with saline placebo, prevents postoperative anemia and improves quality of life for iron-deficient obese patients undergoing bariatric surgery.

  Recruiting China-Japan Friendship Hospital · Beijing · NCT07236788

• Robotic versus laparoscopic conversion to RYGB for revision bariatric surgery

  We will see if robotic surgery or laparoscopy leads to fewer postoperative complications for people having revision bariatric surgery converted to RYGB.

  Recruiting GCS Ramsay Santé pour l'Enseignement et la Recherche · Lyon and 1 other locations · NCT07180316

• Nissen‑Sleeve versus Roux‑en‑Y gastric bypass for reflux in people with severe obesity

  This trial tests whether Nissen‑Sleeve gastrectomy or Roux‑en‑Y gastric bypass better controls GERD symptoms in adults who are eligible for bariatric surgery due to severe obesity.

  Recruiting Jagiellonian University · Krakow · NCT07158008

• Daily protein plus weekly resistance training to prevent muscle loss after bariatric surgery

  The trial will test whether taking a daily protein supplement and doing one supervised resistance workout each week helps people having bariatric surgery keep their muscle mass.

  Recruiting Radboud University Medical Center · Amsterdam and 1 other locations · NCT07156552

• Tranexamic acid to reduce bleeding in sleeve gastrectomy and mini gastric bypass

  This trial will test whether giving tranexamic acid before laparoscopic sleeve gastrectomy or mini gastric bypass reduces bleeding in adults with morbid obesity.

  Recruiting Phase 4 Patel Hospital, Pakistan · Karachi, Sindh · NCT07098780

• Classification and real-time risk-warning system for people having bariatric metabolic surgery

  This project will test whether clinical, lab, and biological data from 2,000 people having bariatric metabolic surgery can be used to classify patients and build a model that warns of postoperative risks.

  Recruiting The Third Xiangya Hospital of Central South University · Changsha, Hunan · NCT07093502

• Implant-based breast reconstruction after bariatric (weight-loss) surgery

  This registry-based project will use national data to see how common breast implants are and whether women who've had bariatric weight-loss surgery have different complication rates after implant-based breast augmentation or reconstruction.

  Recruiting Vastra Gotaland Region · Gothenburg · NCT07059104

• See if same day discharge after bariatric surgery is safe for select patients

  This trial tests whether people having sleeve gastrectomy or gastric bypass can go home the same day or should stay at least one night, to see if ER visits within a week differ.

  Recruiting Vanderbilt University Medical Center · Nashville, Tennessee · NCT07011628

• Using indocyanine green to map blood flow during revisional bariatric surgery

  This test will see if the low guideline dose of indocyanine green or a higher dose gives clearer blood-vessel imaging during revisional bariatric surgery for people with BMI ≥30.

  Recruiting Instituto Mexicano del Seguro Social · Tijuana, Estado de Baja California · NCT07000539

• Predicting Quality of Life After Bariatric Surgery from Pre-Surgery Profiles

  This study tests whether pre-surgical patient traits can predict how quality of life changes after bariatric surgery for adults in the GEROM73 program.

  Recruiting Centre Hospitalier Metropole Savoie · Chambéry, Savoie · NCT06951893

• Investigating the long-term health effects of obesity treatments on women

  This study is trying to see how different obesity treatments affect women's health over time, including their nutrition, bones, muscles, and pregnancy outcomes.

  Recruiting Wageningen University and Research · Elst, Gelderland · NCT06945016

• Exercise program to improve weight, strength, and recovery around bariatric surgery

  This program will test whether a structured exercise plan supported by telerehabilitation helps adults with severe obesity who are having bariatric surgery lose more body fat and gain more strength than usual care.

  Recruiting Instituto de Investigacion Sanitaria La Fe · Valencia, Valencia and 1 other locations · NCT06934681

• Simethicone to reduce gas pain after foregut and bariatric surgery

  This trial will test whether simethicone (Gas-X) reduces gas pain and bloating in adults having foregut operations such as sleeve gastrectomy or gastric bypass.

  Recruiting Phase 4 Madigan Army Medical Center · Tacoma, Washington · NCT06812832

• A new surgical approach to reduce GERD after weight loss surgery

  This study is testing a new type of weight loss surgery to see if it can help reduce acid reflux in people who have had weight loss surgery.

  Recruiting at 2 sites University of California, Irvine · Orange, California and 1 other locations · NCT06783751

• Gum bacteria in people having bariatric surgery with BMI greater than 30

  This will see if people with obesity (BMI ≥30) having bariatric surgery have different gum bacteria depending on whether their BMI is 30–35 or above 35.

  Recruiting University Hospital, Toulouse · Toulouse · NCT06781229

• Endoscopic conversion of sleeve gastrectomy to a new bypass method for reflux and obesity

  This study is testing a new, less invasive procedure to help people who haven't lost enough weight or have gained weight back after sleeve gastrectomy by converting it to a different type of bypass surgery.

  Recruiting at 3 sites Singapore Health Services · Singapore and 2 other locations · NCT06757296

• Monitoring endotracheal tube cuff pressure during laparoscopic bariatric surgery

  This study is testing how changes in the pressure of breathing tubes affect airflow in obese patients during weight loss surgery to help make the procedure safer.

  Recruiting Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital · Kayapınar, Di̇yarbakir · NCT06738875

• Investigation of complications after bariatric surgery in the UK

  This study looks at the problems some people face after weight loss surgery in the UK to see how they are treated and what works best for their recovery.

  Recruiting Bedfordshire Hospitals NHS Foundation Trust · Luton · NCT06738004

• Using tirzepatide before bariatric surgery to improve outcomes

  This study is testing if taking tirzepatide before weight loss surgery can help patients recover better and have fewer complications after the surgery.

  Recruiting Phase 4 University of Kentucky · Lexington, Kentucky · NCT06721507

• Understanding the effects of bariatric surgery and semaglutide in adolescents

  This study is testing how bariatric surgery and the weight loss drug semaglutide can help teenagers aged 12 to 24 lose weight and feel better after surgery.

  Recruiting Phase 1 University of Colorado, Denver · Aurora, Colorado · NCT06575738

• Impact of Sleeve Gastrectomy on Bone and Muscle Health in Men and Women

  This study is trying to see how sleeve gastrectomy affects bone and muscle health in men and women over three years.

  Recruiting CHU de Quebec-Universite Laval · Québec · NCT06547515

• Pain management technique for patients undergoing laparoscopic sleeve gastrectomy

  This study is testing a new pain management technique to see if it can help people recovering from laparoscopic sleeve gastrectomy feel less pain and use fewer opioids after surgery.

  Recruiting Istanbul Medipol University Hospital · Istanbul, Bagcilar · NCT06515691

• Database for studying obesity and metabolic surgery outcomes in China

  This study is collecting information from people in China who have obesity and are having weight loss surgery to see how well these surgeries work in the long run.

  Recruiting Jinan University Guangzhou · Guangzhou, Guangdong · NCT06275061

• Effects of early mobilization on recovery after obesity surgery

  This study tests if getting up and moving around soon after obesity surgery helps patients recover faster and feel less pain.

  Recruiting Esbjerg Hospital - University Hospital of Southern Denmark · Esbjerg, Region Syddanmark · NCT06222151

• Using fecal microbiota transfer to improve diabetes control after bariatric surgery

  This study is testing if a treatment using gut bacteria from healthy donors can help adults with Type 2 Diabetes better manage their blood sugar after having weight loss surgery.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Paris · NCT06192693

• Using imaging to predict weight loss success after bariatric surgery

  This study is testing if looking at CT scans of belly fat can help predict how much weight people will lose and if their type 2 diabetes will improve after bariatric surgery.

  Recruiting China-Japan Friendship Hospital · Beijing · NCT06169033

• Comparing warm humidified CO2 and dry CO2 for pain management in bariatric surgery

  This study is testing if using warm, humidified carbon dioxide during bariatric surgery can help reduce pain and the need for pain medication afterward.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05838300

• Investigating weight loss after mini gastric bypass with a special ring

  This study is testing if a special ring used during mini gastric bypass surgery can help people lose a lot of weight and improve health issues related to obesity over five years.

  Recruiting Ziekenhuisgroep Twente · Almelo · NCT05472922

• Understanding how gut bacteria affect blood sugar after weight loss surgery

  This study is trying to see how gut bacteria affect blood sugar levels in people after they have weight loss surgery, like gastric bypass or sleeve gastrectomy.

  Recruiting at 2 sites Weizmann Institute of Science · Rehovot and 1 other locations · NCT05325736

• Comparing two surgical methods for treating type 2 diabetes

  This study is testing whether a combined surgery for type 2 diabetes can help people with poor blood sugar control feel better than just one type of surgery alone.

  Recruiting Phase 3 Seoul National University Bundang Hospital · Seongnam-si · NCT05211375

• Impact of bariatric surgery on heart function in patients with high blood pressure

  This study is testing how weight loss surgery affects heart function in people with high blood pressure to see if it helps their heart health.

  Recruiting Beijing Friendship Hospital · Beijing, Beijing Municipality · NCT05166954

• Weight monitoring with a connected scale after bariatric surgery

  This project tests whether using a connected scale to monitor weight can guide follow-up care for people who had Roux-en-Y gastric bypass or sleeve gastrectomy two years earlier.

  Recruiting at 2 sites University Hospital, Lille · Boulogne-sur-Mer and 1 other locations · NCT04639778

• Registry of patients visiting the Obesity Clinic

  This study is creating a registry of people visiting the Obesity Clinic to gather information that can help improve treatment and care for obesity.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT04614961

• Impact of Bariatric Surgery on Ovarian Reserve in Obese Women

  This study is testing how bariatric surgery affects the fertility potential of obese women aged 18 to 37 by looking at changes in their hormone levels over a few years.

  Recruiting at 6 sites Assistance Publique - Hôpitaux de Paris · Angers and 13 other locations · NCT04583150

• Comparing metformin addition to standard care after bariatric surgery for diabetes remission

  This study is testing if adding metformin to regular care can help adults who had weight loss surgery keep their diabetes in remission longer.

  Recruiting at 13 sites Phase 3 Assistance Publique - Hôpitaux de Paris · Amiens and 15 other locations · NCT04581447

• Analyzing patient outcomes after bariatric surgery

  This study looks at how patients feel and recover after bariatric surgery to see if certain factors can predict their pain and quality of life in the years following the procedure.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT03490630

• Impact of Bariatric Surgery on Bone Health in Type 2 Diabetes Patients

  This study is testing how sleeve gastrectomy surgery affects bone health in people with type 2 diabetes compared to those who are overweight but don’t have diabetes.

  Recruiting CHU de Quebec-Universite Laval · Montreal, Quebec and 2 other locations · NCT03455868

• Observing outcomes of bariatric surgery patients

  This study looks at the experiences of people who have had bariatric surgery to see how well they are doing with weight loss and any complications they might face.

  Recruiting Hospices Civils de Lyon · Lyon · NCT02857179

• Comparing two types of weight loss surgery for type 2 diabetes treatment

  This study is testing whether two types of weight loss surgery can help people with obesity and type 2 diabetes improve their condition.

  Recruiting Göteborg University · Gothenburg · NCT01984762

NIH-funded research (newest 40 of 50)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How bariatric surgery helps the liver heal by immune cells

  This grant explores how weight-loss surgery may protect the liver from fatty inflammation by changing liver immune cells.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11455274

• Metabolic gut-macteria pathways after bariatric surgery

  This grant explores how bariatric surgery changes gut microbes and their chemicals to improve glucose control in adults with type 2 diabetes.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11449773

• Comparing medicines and weight-loss surgery for liver disease linked to metabolic problems

  This program looks at how two drugs and bariatric surgery work for adults with metabolic dysfunction–associated steatohepatitis (MASH) and liver fibrosis.

  NIH research Seattle Inst for Biomedical/clinical Res · Seattle, United States · NIH-11448529

• Decoding how bariatric surgery changes brain signals to help weight loss

  A research project looks at how weight-loss surgeries like VSG and RYGB alter brain cell activity related to appetite and metabolism to understand why these procedures work.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11417325

• Glucagon's diabetes-related effects after bariatric surgery

  This project looks at how glucagon affects blood sugar in adults with type 2 diabetes, comparing people who have had bariatric surgery to those who haven’t.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11413804

• BREW ME Model: How bariatric surgery changes alcohol use biology

  A study investigates why some people drink more or develop hazardous drinking after bariatric surgery, using biology and behavior to understand the change.

  NIH research Sanford Research North · Fargo, United States · NIH-11408840

• Gut bacteria changes after bariatric surgery and colorectal cancer risk

  This study will follow adults who had bariatric surgery to understand how changes in the gut microbiome and bile acids might influence colorectal cancer risk.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11401981

• Pharmacotherapy and lifestyle support to prevent weight regain after bariatric surgery

  A large, well-designed trial tests whether adding medication to lifestyle coaching can help people keep weight off after bariatric surgery.

  NIH research University of California-Irvine · Irvine, United States · NIH-11399771

• Alcohol after bariatric surgery: how anesthesia-free drinking changes after weight loss surgery

  Aims to understand how bariatric surgery changes how people absorb and feel alcohol so clinicians can guide safer drinking after surgery.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11396970

• How bariatric surgery changes brain responses to food and alcohol

  This project looks at how brain signals related to food and alcohol change before and after sleeve or Roux-en-Y gastric bypass surgery, and how those changes relate to what people actually eat and drink.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11381840

• Remotely Delivered Behavioral Help to Keep Weight Off After Bariatric Surgery

  A remotely delivered behavioral program called ABTi is tested to help people who have regained weight after bariatric surgery keep the benefits of their operation.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11369604

• Early use of semaglutide after weight-loss surgery in teens and young adults

  A trial tests starting the obesity drug semaglutide soon after bariatric surgery in teens and young adults to help keep weight off.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11366452

• Gut bacteria and bile acids linked to heart function after bariatric surgery

  This study looks at how gut microbes and bile acids after sleeve gastrectomy might improve heart function in people with obesity-related diastolic problems.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11326772

• Monthly risedronate pill to protect bones after sleeve gastrectomy

  This will see if a once-monthly risedronate pill helps protect bone health for people who have had sleeve gastrectomy.

  NIH research Wake Forest University · Winston-Salem, United States · NIH-11322517

• Bone structure and strength after sleeve gastrectomy with risedronate

  This project compares the osteoporosis drug risedronate to a placebo to help protect bone structure and strength in people aged 40 and older having sleeve gastrectomy.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11305223

• Comparing bariatric (weight‑loss) surgery with GLP‑1 and SGLT‑2 diabetes medicines for people with obesity and type 2 diabetes

  This project compares long-term benefits and safety of weight‑loss surgery versus GLP‑1 and SGLT‑2 diabetes medicines for adults who have obesity and type 2 diabetes.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11290742

• Acceptance and Commitment Therapy to boost activity and keep weight off after bariatric surgery

  This project uses Acceptance and Commitment Therapy to help adults who had bariatric surgery stay active and maintain weight loss.

  NIH research Hartford Hospital · Hartford, United States · NIH-11249641

• Weight-loss surgery effects on memory and brain health in adults with obesity and type 2 diabetes

  This project tracks whether bariatric (weight-loss) surgery helps thinking and brain health in adults with severe obesity and type 2 diabetes by measuring changes before and after surgery.

  NIH research University of Florida · Gainesville, United States · NIH-11249634

• Why alcohol use can increase after bariatric (weight-loss) surgery

  This project looks at whether changes in gut bacteria and brain reward after bariatric surgery make alcohol more rewarding for people who have had the operation.

  NIH research Sanford Research North · Fargo, United States · NIH-11190847

• How weight-loss (bariatric) surgery changes gut bacteria and colon cancer risk

  This project looks at how gut bacteria, bile acids, and other body changes after bariatric surgery might affect future colorectal (colon) cancer risk in adults who had the operation.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11182510

• Parents' weight loss before pregnancy and children's long-term health

  This project looks at whether mothers who lose weight from bariatric surgery before pregnancy have children who grow into healthier weights through early childhood.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11170450

• Controlling loss-of-control (binge) eating and weight after bariatric surgery

  This project offers behavioral counseling and a medication option to help adults who have loss-of-control eating after weight-loss surgery keep weight off.

  NIH research Yale University · New Haven, United States · NIH-11168704

• How alcohol affects people after weight-loss (bariatric) surgery

  This project looks at how people's bodies process alcohol and how alcohol makes them feel after sleeve gastrectomy or gastric bypass surgery.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11163294

• Combining medication and behavioral therapy to improve weight after weight-loss surgery

  This project compares medication plus structured behavior therapy to help adults keep weight off after bariatric (metabolic) surgery.

  NIH research Yale University · New Haven, United States · NIH-11162361

• How nutrient delivery affects weight loss and brain signaling after bariatric surgery

  This study is looking at how quickly nutrients reach the gut and how that affects weight loss and brain signals in people having bariatric surgery, to help us understand how gut health can influence feelings of fullness and food choices.

  NIH research Lsu Pennington Biomedical Research Ctr · Baton Rouge, United States · NIH-11143895

• Understanding how bariatric surgery affects Alzheimer's disease

  This study is looking at how weight loss surgery, like sleeve gastrectomy, might help improve brain health and reduce the risk of Alzheimer's in older adults who are dealing with obesity and type 2 diabetes, so you can learn more about how this surgery could benefit your overall health and thinking skills.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11140068

• Support for Weight Management After Bariatric Surgery

  This program helps people who have had bariatric surgery and are starting to regain weight learn new ways to keep the weight off.

  NIH research Temple Univ of the Commonwealth · Philadelphia, United States · NIH-11127608

• Understanding how gut bacteria changes after weight loss surgery can improve heart function.

  This study is looking at how sleeve gastrectomy, a type of weight-loss surgery, can help improve heart function in people with obesity-related heart issues by examining changes in gut bacteria and bile acids after the surgery.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11103193

• How brain signals relate to food and alcohol changes after weight-loss surgery

  This project looks at how brain activity, eating of high- versus low-calorie foods, and alcohol use change in people before and after two common bariatric surgeries.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11099945

• Investigating the impact of fat around the heart on diabetes and heart health in young people undergoing weight loss surgery

  This study is looking at how the fat around the heart affects heart health in teenagers with type 2 diabetes who are having weight loss surgery, using special heart scans to find out more about it and see how different diabetes treatments might help.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11061185

• Comparing the effectiveness and safety of surgery and medications for obesity and type 2 diabetes

  This study is looking at how well metabolic surgery works compared to certain medications for treating obesity and type 2 diabetes, so that patients and doctors can better understand the best options for managing these conditions, especially for those who might not always get the best care.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11051211

• Helping bariatric surgery patients stay active and maintain weight loss through therapy.

  This study is looking at how a special therapy called Acceptance and Commitment Therapy (ACT) can help people who have had weight loss surgery feel more motivated to stay active and exercise regularly, by connecting their personal values to their health goals.

  NIH research Hartford Hospital · Hartford, United States · NIH-11040988

• Investigating how risedronate can prevent bone loss after bariatric surgery

  This study is looking at whether the medication risedronate can help prevent bone loss in people over 40 who have had sleeve gastrectomy for weight loss, and it will involve 120 participants taking either the medication or a placebo for six months.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11038003

• Understanding how bariatric surgery and semaglutide affect adolescents' health

  This study is looking at how weight loss surgery can help teenagers with severe obesity, and whether adding a medication called semaglutide can make the results even better, all while checking their health over a year to find out what helps them succeed.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11011271

• How gut bacteria changes after weight loss surgery may affect colorectal cancer risk

  This study is looking at how changes in the bacteria in your gut after weight loss surgery might affect your chances of getting colorectal cancer, and it’s for people who have had or are considering bariatric surgery.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10923948

• Understanding how gut cells change after bariatric surgery

  This study is looking at how weight loss surgery, called vertical sleeve gastrectomy, changes certain gut cells that help control weight and blood sugar, with the hope of finding new, non-surgical treatments for obesity and type 2 diabetes that could help patients like you.

  NIH research University of Tennessee Health Sci Ctr · Memphis, United States · NIH-10909971

• Understanding how bariatric surgery affects brain signals related to weight loss

  This study is looking at how weight loss surgery helps people with obesity by checking certain markers in the fluid around the brain, to see how changes in the gut affect how our bodies manage energy, and it's for anyone interested in understanding the benefits of surgeries like gastric bypass and sleeve gastrectomy co

  NIH research Columbia University Health Sciences · New York, United States · NIH-10903831

• Medications plus lifestyle counseling to treat weight regain after bariatric surgery

  This project compares two weight-loss medicines combined with diet and lifestyle counseling to help people who have regained weight after bariatric surgery lose weight.

  NIH research University of California-Irvine · Irvine, United States · NIH-10897280

• Investigating how weight loss surgery before pregnancy affects children's health.

  This study is looking at how losing weight through surgery before having a baby might help reduce the chances of obesity and health problems in their children, and it’s for women who are considering or have had weight loss surgery.

  NIH research Oregon Health & Science University · Portland, United States · NIH-10895976

• Improving weight loss outcomes after metabolic and bariatric surgery

  This study is looking at how pairing therapy with medication can help people who have had weight loss surgery keep the weight off and feel better afterward.

  NIH research Yale University · New Haven, United States · NIH-10886038

Related topics

Quick answers

How many Bariatric Surgery clinical trials are recruiting right now?

60, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 23 countries. The most sites are in France (11 trials), United States (8 trials), Turkey (Türkiye) (8 trials), China (5 trials), Netherlands (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 4, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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