Understanding how gut cells change after bariatric surgery
The role of enteroendocrine cell differentiation in the success of bariatric surgery
This study is looking at how weight loss surgery, called vertical sleeve gastrectomy, changes certain gut cells that help control weight and blood sugar, with the hope of finding new, non-surgical treatments for obesity and type 2 diabetes that could help patients like you.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tennessee Health Sci Ctr NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-10909971 on NIH RePORTER |
What this research studies
This research investigates how bariatric surgery, specifically vertical sleeve gastrectomy (VSG), leads to changes in gut cells that produce hormones important for weight loss and blood sugar control. The study aims to understand the mechanisms behind the increase in these hormone-secreting cells after surgery, which could help replicate the benefits of surgery through non-invasive treatments. By examining the differentiation of enteroendocrine cells and their role in hormone secretion, the research seeks to uncover potential new therapies for obesity and type 2 diabetes. Patients may benefit from insights that could lead to improved treatment options without the need for surgery.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are struggling with obesity and type 2 diabetes.
Not a fit: Patients who are not overweight or do not have type 2 diabetes may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to non-invasive treatments that mimic the weight loss and diabetes remission effects of bariatric surgery.
How similar studies have performed: Other research has shown promising results in understanding gut hormone mechanisms, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
Memphis, United States
- University of Tennessee Health Sci Ctr — Memphis, United States (Active)
Researchers
- Principal investigator: Kim, Ki Suk — University of Tennessee Health Sci Ctr
- Study coordinator: Kim, Ki Suk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.