Condition

Obesity, Morbid clinical trials and research

• 58Clinical trials
• 1New in 30 days
• 19Countries

Newest Obesity, Morbid clinical trials

All recruiting trials (58)

• Glycemic variability after SASI versus Roux-en-Y gastric bypass

  This trial tests whether SASI or Roux-en-Y gastric bypass leads to different glucose fluctuations in adults with severe obesity using continuous glucose monitoring.

  Recruiting Hospitales Universitarios Virgen del Rocío · Seville, Sevilla · NCT07872397

• Postoperative nausea, vomiting and pain after bariatric surgery in Sweden

  This study looks at how often people have nausea, vomiting, and pain after bariatric surgery in Sweden and whether anesthesia type or regional blocks affect those outcomes.

  Recruiting at 2 sites Umeå University · Sundsvall and 1 other locations · NCT07797374

• Low-impact laparoscopy for sleeve gastrectomy in adults with obesity

  This will see if low-pressure, small-incision laparoscopy reduces post-surgery pain and improves breathing after sleeve gastrectomy in adults with obesity.

  Recruiting Fondazione Policlinico Universitario Campus Bio-Medico · Rome, Italy · NCT07119437

• Tranexamic acid to reduce bleeding in sleeve gastrectomy and mini gastric bypass

  This trial will test whether giving tranexamic acid before laparoscopic sleeve gastrectomy or mini gastric bypass reduces bleeding in adults with morbid obesity.

  Recruiting Phase 4 Patel Hospital, Pakistan · Karachi, Sindh · NCT07098780

• Predicting Quality of Life After Bariatric Surgery from Pre-Surgery Profiles

  This study tests whether pre-surgical patient traits can predict how quality of life changes after bariatric surgery for adults in the GEROM73 program.

  Recruiting Centre Hospitalier Metropole Savoie · Chambéry, Savoie · NCT06951893

• Endoscopic treatment for overweight and mild obesity using Orbera365

  This study is testing whether the Orbera365 intragastric balloon can help people who are overweight or mildly obese lose weight over a year.

  Recruiting Kaiser Clinic and Hospital · Santo André, São Paulo · NCT06785233

• Gum bacteria in people having bariatric surgery with BMI greater than 30

  This will see if people with obesity (BMI ≥30) having bariatric surgery have different gum bacteria depending on whether their BMI is 30–35 or above 35.

  Recruiting University Hospital, Toulouse · Toulouse · NCT06781229

• Adding naltrexone–bupropion extended‑release to sleeve gastrectomy to improve weight loss

  This trial will test whether taking naltrexone–bupropion extended‑release after sleeve gastrectomy helps adults with obesity lose more weight and improve related health problems.

  Recruiting Phase 4 Laval University · Québec, Quebec · NCT06620562

• Evaluating hormone levels in obese men

  This study is testing how hormone levels in obese men affect their bone health and heart disease risk.

  Recruiting Istituto Auxologico Italiano · Oggebbio, Verbania · NCT06341699

• Effects of a diet with essential amino acids on weight loss in obese patients

  This study is testing if adding essential amino acids to a low-calorie diet can help obese people lose weight while keeping their muscle mass.

  Recruiting Istituto Auxologico Italiano · Oggebbio, Verbania · NCT06309563

• Characterizing diabetes and obesity in Greenlandic patients

  This study is trying to learn more about how genetics and environment affect type 2 diabetes and obesity in Greenlandic people, while also looking at related health issues like sleep apnea.

  Recruiting Steno Diabetes Center Greenland · Nuuk, Sermersooq · NCT06264427

• Understanding genetic factors that affect weight loss after bariatric surgery

  This study is trying to find out if certain genes can help predict how well people with severe obesity will lose weight after having bariatric surgery.

  Recruiting Institut de Recerca Biomèdica de Lleida · Lleida, Leida · NCT06226194

• Using a new endoscopy technique for bariatric patients

  This study is testing a new, less invasive endoscopy method for bariatric patients to see if it can improve safety and reduce costs when checking for stomach and digestive issues.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT06200961

• Optimizing mechanical ventilation for morbidly obese patients with ARDS

  This study is testing if adjusting breathing machine settings based on pressure measurements can help morbidly obese patients with severe lung problems breathe better than standard methods.

  Recruiting at 5 sites Assistance Publique - Hôpitaux de Paris · Angers and 4 other locations · NCT06119516

• Identifying predictors of weight loss and metabolic health after bariatric surgery

  This study is trying to find out what factors can help predict how well people with insulin resistance will lose weight and improve their health after having bariatric surgery.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Gouda, South Holland and 2 other locations · NCT05987631

• Comparing robotic and traditional laparoscopic surgery for obese patients with early endometrial cancer

  This study is testing whether robotic surgery works better than traditional laparoscopic surgery for morbidly obese patients with early endometrial cancer.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT05974995

• Comparing Airtraq for intubation in obese and non-obese men

  This study is testing how well the Airtraq video laryngoscope works for intubating men with morbid obesity compared to non-obese men to see if it makes the process easier and faster.

  Recruiting Kocaeli University · Iamit and 1 other locations · NCT05927519

• Using noninvasive breathing support for severely obese patients after extubation

  This study is testing if using a combination of noninvasive breathing support methods can help severely obese patients breathe better after being taken off a ventilator and reduce the chances of needing to be put back on one.

  Recruiting at 4 sites Rush University Medical Center · Chicago, Illinois and 4 other locations · NCT05918575

• Endoscopic sleeve gastroplasty for obese kidney transplant candidates

  This study is testing if a procedure called endoscopic sleeve gastroplasty can help obese patients with kidney disease lose enough weight to qualify for a kidney transplant.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome · NCT05917795

• Using light therapy to relieve chronic knee pain in obese patients preparing for weight loss surgery

  This study is testing whether light therapy can help reduce knee pain and improve movement in obese patients getting ready for weight loss surgery.

  Recruiting Phase 2/3 University of Nove de Julho · Goiânia, Goiás · NCT05816798

• Sleeve gastrectomy or OverStitch endoscopic suturing to restore fullness after weight-loss surgery

  This study will test whether sleeve gastrectomy or endoscopic OverStitch suturing helps people with severe obesity or those with post-bariatric weight regain feel full with smaller meals.

  Recruiting Istituto Auxologico Italiano · Milan · NCT05777928

• Endoscopic Antral Myotomy for Weight Loss

  This study is testing a new weight loss procedure called Pylorus Sparing Antral Myotomy to see if it helps people with obesity lose weight safely and effectively on its own.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT05711758

• Comparing two surgical options for treating morbid obesity

  This study is testing whether a new type of weight loss surgery called SASI works better than the traditional sleeve gastrectomy for people with severe obesity.

  Recruiting at 2 sites Oslo University Hospital · Tønsberg, Vestfold and 1 other locations · NCT05611697

• Analyzing multi-omics data for personalized treatment of fatty liver disease linked to obesity

  This study is trying to see if using advanced data analysis can help create personalized treatments for people with fatty liver disease caused by obesity.

  Recruiting Institut Investigacio Sanitaria Pere Virgili · Reus, Tarragona · NCT05554224

• Understanding why some patients don't lose weight after bariatric surgery

  This study is trying to find out why some people don’t lose as much weight as expected after bariatric surgery, focusing on the role of gut hormones to help improve their results.

  Recruiting Imperial College London · London · NCT05404061

• Evaluating Propofol Dosing in Obese Patients

  This study tests whether using total body weight or adjusted body weight for dosing propofol can help keep morbidly obese patients safely anesthetized during long surgeries.

  Recruiting Phase 4 Sir Ganga Ram Hospital · New Delhi, National Capital Territory of Delhi · NCT05305313

• Improving outcomes for patients with failed sleeve gastrectomy using a new surgical approach

  This study is testing a new type of surgery called SADI-S to see if it can help people who didn't have success with their previous sleeve gastrectomy lose weight and improve their health.

  Recruiting Laval University · Québec, Quebec · NCT05242835

• Comparing two types of distal gastric bypass for patients with weight regain after gastric bypass surgery

  This study is testing two different types of gastric bypass surgery to see which one helps people who have regained weight after their first surgery lose weight more effectively.

  Recruiting at 6 sites St. Antonius Hospital · Arnhem, Gelderland and 7 other locations · NCT04894838

• Survey on bariatric surgery for adolescents

  This study is trying to see how well laparoscopic adjustable gastric banding works for teenagers aged 14-20 who are having bariatric surgery, focusing on weight loss and any health issues that might come up.

  Recruiting University Hospital, Angers · Angers, Maine Et Loire · NCT04766801

• Evaluating stomach and esophagus changes after gastric bypass surgery

  This study is testing how gastric bypass surgery affects the stomach and esophagus in people with obesity who haven't lost weight through other methods.

  Recruiting Spital Limmattal Schlieren · Schlieren, Canton of Zurich · NCT04422405

• Using spinal cord stimulation to activate brown fat for weight loss and diabetes management

  This study is testing if spinal cord stimulation can help people with obesity and Type 2 diabetes by activating fat that burns calories to promote weight loss and better diabetes control.

  Recruiting Oregon Health and Science University · Portland, Oregon · NCT04326192

• Understanding the connection between obesity and liver inflammation

  This study looks at how extra fat around the liver and inflammation in body fat affect liver health and insulin resistance in people with obesity, especially those having gastric bypass surgery.

  Recruiting Mayo Clinic · Scottsdale, Arizona · NCT04232566

• Registry for bariatric surgery quality control

  This study is setting up a registry to track the results and safety of bariatric surgery for people who are severely obese to help improve surgical practices.

  Recruiting Sheba Medical Center · Ramat Gan · NCT04040413

• Effects of Bariatric Surgery and Lifestyle Changes on Fat and Liver Health

  This study is testing how bariatric surgery and lifestyle changes affect fat and liver health in people with obesity and related metabolic issues.

  Recruiting Chinese University of Hong Kong · Hong Kong, Shatin · NCT03875625

• Effects of weight loss on insulin regulation after bariatric surgery

  This study tests if losing a lot of weight after bariatric surgery helps people with severe obesity improve their insulin function and reduce inflammation over a year.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT03868592

• Effects of bariatric surgery on paracetamol absorption

  This study is trying to see how bariatric surgery affects how well paracetamol works for people getting ready for gastric bypass or sleeve gastrectomy.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03538457

• Investigating how bariatric surgery affects the absorption of valsartan

  This study is testing how bariatric surgery affects how well the heart medication valsartan is absorbed in patients getting gastric bypass or sleeve gastrectomy.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03535376

• Examining the impact of fatty liver disease in bariatric patients

  This study is trying to see how non-alcoholic fatty liver disease affects health outcomes in people with obesity who are having bariatric surgery compared to those who aren't.

  Recruiting Esbjerg Hospital - University Hospital of Southern Denmark · Esbjerg · NCT03535142

• Impact of bariatric surgery on the absorption of venlafaxine

  This study is trying to see how bariatric surgery affects how well the depression and anxiety medication venlafaxine works for patients getting ready for these surgeries.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03532477

• Impact of bariatric surgery on metoprolol absorption

  This study is testing how bariatric surgery affects the way the body absorbs metoprolol, a common heart medication, to help doctors better manage treatment for patients who have had this surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03519906

• Impact of bariatric surgery on the effectiveness of losartan

  This study is testing how bariatric surgery affects the way the blood pressure medication losartan works in patients getting ready for surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03519893

• Impact of bariatric surgery on the absorption of lercanidipine

  This study looks at how bariatric surgery affects how well the medication lercanidipine is absorbed in patients who have had weight loss surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03497156

• Impact of bariatric surgery on lamotrigine absorption

  This study is testing how bariatric surgery affects the way the body absorbs lamotrigine, a medication for epilepsy and mood stabilization, in patients getting ready for these surgeries.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03497143

• Effects of bariatric surgery on the medication irbesartan

  This study looks at how bariatric surgery affects the way the body processes the medication irbesartan in patients getting ready for surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03476603

• Impact of Bariatric Surgery on Ibuprofen Absorption

  This study looks at how bariatric surgery affects how well ibuprofen is absorbed in patients to help manage their medications better after surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03476577

• Impact of bariatric surgery on the effectiveness of hydrochlorothiazide

  This study looks at how bariatric surgery affects how well the blood pressure medication hydrochlorothiazide works for patients getting ready for surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03476551

• Impact of Bariatric Surgery on Gabapentin Absorption

  This study looks at how bariatric surgery affects how well gabapentin, a medication for nerve pain and seizures, is absorbed by patients after their surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03476538

• Impact of bariatric surgery on fluoxetine absorption

  This study looks at how bariatric surgery affects the way the body absorbs fluoxetine, a medication for depression, to see if it changes how well the drug works for people who have had the surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03476525

• Impact of bariatric surgery on the effectiveness of enalapril

  This study is testing how bariatric surgery affects how well the heart medication enalapril works in people who have had the surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03460366

• Impact of bariatric surgery on the effects of candesartan

  This study is testing how bariatric surgery affects how well the medication candesartan works in people who have had the surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03460327

• Impact of Bariatric Surgery on Bone Health in Type 2 Diabetes Patients

  This study is testing how sleeve gastrectomy surgery affects bone health in people with type 2 diabetes compared to those who are overweight but don’t have diabetes.

  Recruiting CHU de Quebec-Universite Laval · Montreal, Quebec and 2 other locations · NCT03455868

• Effects of bariatric surgery on the medication chlorprothixene

  This study looks at how bariatric surgery affects how well the medication chlorprothixene works in patients preparing for gastric bypass or sleeve gastrectomy.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03449485

• Impact of bariatric surgery on how quetiapine is processed in the body

  This study looks at how bariatric surgery changes the way the body processes quetiapine, a medication for mental health, to help doctors better manage treatment for patients who have had the surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03449472

• Effects of bariatric surgery on the absorption of apixaban

  This study is testing how bariatric surgery affects the way the blood thinner apixaban is absorbed in patients getting ready for the surgery.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03448783

• Impact of Bariatric Surgery on Ramipril Absorption

  This study is testing how bariatric surgery affects the way the body absorbs the heart medication ramipril in people who have had gastric bypass or sleeve gastrectomy.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT03440177

• Comparing health risks after obesity treatment methods

  This study looks at the health risks of malnutrition, bone disease, and oral health problems in people who have had obesity surgery compared to those treated with regular methods over ten years.

  Recruiting Göteborg University · Gothenburg · NCT03152617

• Effects of bariatric surgery on the absorption of amlodipine

  This study is testing how bariatric surgery affects the way the body absorbs amlodipine, a medication for high blood pressure, in patients getting ready for these surgeries.

  Recruiting Norwegian University of Science and Technology · Trondheim · NCT02904291

• Long-term follow-up of severely obese patients after bariatric surgery

  This study is trying to see how well different types of weight loss surgery work for severely obese patients over the long term and how it affects their health and quality of life.

  Recruiting University Hospital, Montpellier · Montpellier · NCT02310178

Related topics

Quick answers

How many Obesity, Morbid clinical trials are recruiting right now?

58, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in Norway (20 trials), Italy (6 trials), United States (6 trials), France (5 trials), Spain (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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