Simethicone to reduce gas pain after foregut and bariatric surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center, randomized, placebo-controlled Phase 4 trial enrolls adult patients undergoing foregut procedures at Madigan Army Medical Center. Participants complete a baseline PROMIS Gastrointestinal Gas and Bloating survey, are randomized to receive either simethicone 80 mg or placebo four times daily after surgery, and repeat the PROMIS survey and the APS-POQ-R pain questionnaire 24 hours postoperatively (and daily if admitted longer). The research pharmacist and study statistician are the only unblinded personnel, and all other team members and patients are blinded to allocation. The study is designed to gather safety data and measure symptomatic benefit of simethicone in the immediate postoperative period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Foregut procedures

Exclusion Criteria:

* Non-foregut procedures
* Allergy to simethicone
* Pregnancy or breastfeeding
* Minors under 18 years of age

Where it's running

• Madigan Army Medical Center
  Tacoma, Washington, United States Recruiting

Study contacts

• Study coordinator: Brooklyn Williams, DO
• Email: brooklyn.c.williams3.mil@health.mil
• Phone: (253) 968-3105

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.