Condition

Obesity (Disorder) clinical trials and research

• 31Clinical trials
• 1New in 30 days
• 14Countries

Newest Obesity (Disorder) clinical trials

All recruiting trials (31)

• Weight-loss drugs tirzepatide vs. semaglutide in adults with obesity

  This trial tests whether 12 weeks of tirzepatide or semaglutide have different effects on energy balance in adults with obesity but no diabetes.

  Recruiting Phase 4 McMaster University · Hamilton, Ontario · NCT07900074

• Body composition changes after starting GLP-1 therapies in adults with obesity or type 2 diabetes

  This study will follow adults with obesity and/or type 2 diabetes who are starting or adjusting a GLP-1 receptor agonist to see how their muscle and fat change over about a year.

  Recruiting at 2 sites Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Mexico City, Mexico City and 1 other locations · NCT07835360

• Synbiotic for cognitive function in adults with obesity

  A synbiotic containing Lactobacillus acidophilus and inulin is being tested to see if it improves cognitive function in adults with obesity and mild cognitive impairment.

  Recruiting Anahuac University · Huixquilucan, State of Mexico · NCT07810517

• Digital dietary help for people on GLP-1 therapy to reach better blood sugar and weight

  This trial tests whether adding a digital dietary program (NutriSteppe) to usual care helps adults on GLP-1 medications see better blood sugar control and weight results.

  Recruiting Kazakh Academy of Nutrition · Almaty · NCT07728669

• Dramatherapy Added to Physical Activity for Obesity Care

  This trial tests whether adding dramatherapy to a standard adapted physical activity program helps adults with obesity in bariatric or medical care improve psychosocial well‑being and weight-related outcomes.

  Recruiting Universite du Littoral Cote d'Opale · Blendecques, Hauts-de-France · NCT07685483

• Sedentary-time reduction and light activity plan to boost fitness before and after bariatric surgery

  This study tests whether a structured program to reduce sitting and increase light physical activity can improve fitness and post-surgery outcomes for women planning bariatric surgery.

  Recruiting Hospital de Sao Sebastiao · Santa Maria da Feira · NCT07663942

• Genetic predictors of weight loss with GLP-1/GIP therapies in obesity

  This study tests whether a genetic risk score and specific obesity-related SNPs can predict how much weight adults with obesity will lose on semaglutide or tirzepatide.

  Recruiting National and Kapodistrian University of Athens · Athens · NCT07653412

• Intensive lifestyle changes after AF ablation in people who are overweight

  The study tests whether an intensive diet and exercise program after AF ablation helps overweight patients do better than standard follow-up care.

  Recruiting National Taiwan University Hospital · Taipei · NCT07618741

• How moderate, vigorous, and short maximal exercise affect inflammation in sedentary overweight adults

  This study will test whether three types of exercise—moderate-intensity, vigorous-intensity, and short maximal bouts—can reduce inflammation in sedentary adults with BMI 25.0–30.0 kg/m².

  Recruiting Department of Cardiology German Heart Center Munich TUM University Hospital · München, Bavaria · NCT07543666

• Preventing obesity-related HFpEF

  We will follow about 250 adults with obesity who are having metabolic bariatric surgery to see if weight loss prevents or reverses early HFpEF.

  Recruiting Zuyderland Medisch Centrum · Heerlen, Limburg · NCT07539766

• Integrated Traditional Chinese and Western medicine care for adults with obesity

  This project will try combining traditional Chinese medicine and Western medical care in adults with obesity to see how well that combination works in everyday clinical practice.

  Recruiting Hubei Hospital of Traditional Chinese Medicine · Wuhan, Hubei · NCT07448090

• Potassium sorbate and short-term eating in adults with obesity

  This pilot will see if a one-time dose of potassium sorbate changes how much adults with obesity eat over the next 24 hours compared with a placebo after they reduce similar additives in their diet.

  Recruiting McMaster University · Hamilton, Ontario · NCT07437430

• Tirzepatide effects on skeletal muscle in women with obesity

  This trial will test whether tirzepatide changes muscle strength, size, quality, and metabolism in premenopausal adult women with obesity over 24 weeks.

  Recruiting University Medical Centre Ljubljana · Ljubljana · NCT07373834

• Side-to-side duodeno-ileostomy with magnets versus semaglutide for adults with obesity and type 2 diabetes

  This trial tests whether a magnet-assisted side-to-side duodeno-ileostomy surgery or the medication semaglutide works better to improve blood sugar control and weight in adults with obesity and type 2 diabetes.

  Recruiting GT Metabolic Solutions, Inc. · Westmount, Quebec · NCT07317115

• Recovery after stopping semaglutide: effects on weight, heart risk, and appetite

  This trial will test whether gradually lowering semaglutide instead of stopping it suddenly changes weight, heart risk markers, and appetite hormones in adults with obesity who lost at least 10% of their weight on semaglutide.

  Recruiting Phase 3 Mount Sinai Hospital, Canada · Toronto, Ontario · NCT07294950

• Different weekly feedback messages to support weight loss

  This project will test whether different weekly feedback messages delivered via a smartphone app help adults with overweight or obesity lose weight.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT07292389

• A gut-microbiota–friendly diet after bariatric surgery to help eating habits and taste

  This tests whether a diet designed to increase gut microbiota diversity helps adults who have had sleeve gastrectomy or Roux-en-Y gastric bypass keep weight off, change food preferences and taste/smell, and improve gut-related health compared with standard nutrition counseling.

  Recruiting Hospices Civils de Lyon · Lyon and 2 other locations · NCT07268508

• Tirzepatide for weight and health in postmenopausal women with HR+ breast cancer

  This study tests whether weekly tirzepatide can help weight and overall health in postmenopausal women who have hormone receptor–positive breast cancer and obesity.

  Recruiting Phase 4 Weill Medical College of Cornell University · New York, New York · NCT07257484

• Effects of a fasting-mimicking 5-day program and a Longevity Diet on age-related risk factors and aging biomarkers

  This trial will test whether a 5-day fasting-mimicking diet, alone or combined with a Longevity Diet, helps improve body weight, body composition, cardiovascular risk markers, and aging-related biomarkers in adults aged 30–65, many of whom are overweight or have metabolic risk.

  Recruiting Fondazione Valter Longo · Varapodio, Calabria, Italy · NCT07255300

• Cognitive changes after bariatric surgery using VR Neurotracker and Neuropsi testing

  This study will test whether bariatric surgery combined with virtual‑reality Neurotracker sessions improves thinking and memory in adults with morbid obesity scheduled for surgery.

  Recruiting Hospital General de México Dr. Eduardo Liceaga · Montreal, Quebec and 1 other locations · NCT07229924

• Weekly self-monitoring feedback and goal prompts to support weight loss

  This trial will test different weekly feedback messages and goal prompts delivered by smartphone to see which help adults with overweight or obesity stick to tracking their diet, activity, and weight and lose more weight.

  Recruiting Wake Forest University Health Sciences · Milwaukee, Wisconsin · NCT07227051

• Very low-energy ketogenic program for adults with type 1 diabetes and obesity using an automated insulin system

  This will test whether a 4-week very low-energy ketogenic diet delivered with meal replacements can help adults with type 1 diabetes and obesity who use an advanced hybrid closed‑loop insulin system lose weight safely.

  Recruiting Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · Bari, Italy · NCT07185555

• GLP-1 medication effects on reproductive hormones in obese teenage girls with PCOS

  We will test whether GLP-1 medications are linked to changes in reproductive hormones and menstrual cycles in obese adolescent girls with PCOS.

  Recruiting Nemours Children's Clinic · Jacksonville, Florida · NCT07169136

• Repeated far‑infrared sauna bathing for adults with obesity

  This tests whether 30 sessions of far‑infrared sauna bathing can improve heart and metabolic health in adults with obesity.

  Recruiting University of Oregon · Eugene, Oregon · NCT07158047

• Wearable monitoring of walking and arm movement in adults with neuromuscular or metabolic movement disorders

  This project uses a wrist/ankle wearable to continuously monitor walking and upper-limb movement in ambulant adults with neuromuscular diseases or obesity to see if digital measures like stride speed track real-life motor function.

  Recruiting Centre Hospitalier Universitaire de Liege · Liège · NCT07136844

• How weight-loss surgery changes blood vessel health and inflammation

  This project will try to see if weight-loss surgery improves blood vessel function and reduces inflammation in adults with obesity.

  Recruiting Maria Cecilia Hospital · Cotignola, Ravenna · NCT07131605

• Tirzepatide versus liraglutide effects on bone and body composition in severe obesity.

  This study will test whether tirzepatide or liraglutide lead to different changes in bone health and body composition in adults aged 30–65 with severe obesity (BMI ≥40).

  Recruiting National and Kapodistrian University of Athens · Athens, Attica · NCT07094568

• How kidneys handle protein and salt in people with HFpEF and obesity

  This study will test how kidneys process protein and salt after a high-protein, high-sodium meal in adults with obesity and heart failure with preserved ejection fraction compared with healthy and obese-only adults.

  Recruiting University of Mississippi Medical Center · Jackson, Mississippi · NCT07052539

• Personalized approaches to prevent non-communicable diseases in Kazakhstan

  This study is trying to see if analyzing DNA can help create personalized health plans to prevent diseases like heart problems and diabetes for people in Kazakhstan.

  Recruiting Asfendiyarov Kazakh National Medical University · Almaty, Kazakhstan · NCT06953180

• Combining a very low calorie ketogenic diet with naltrexone/bupropion for weight regain after bariatric surgery

  This study is testing if a very low calorie ketogenic diet combined with a medication can help people who have regained weight after bariatric surgery lose weight again.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant and 1 other locations · NCT06881485

• Metabolic response to a lifestyle program with or without semaglutide in adolescents with obesity

  This trial will test whether adding semaglutide to a behavioral weight-management program helps adolescents (12–17) with obesity avoid the usual drop in metabolism that follows weight loss.

  Recruiting Phase 4 McMaster University · Hamilton, Ontario · NCT06852391

Related topics

Quick answers

How many Obesity (Disorder) clinical trials are recruiting right now?

31, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in Canada (6 trials), United States (6 trials), Italy (3 trials), Mexico (3 trials), Kazakhstan (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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