Improving weight loss outcomes after metabolic and bariatric surgery
Official title: Behavioral and Pharmacological Treatments to Enhance Weight Outcomes after Metabolic and Bariatric Surgery
Funded at Yale University · NIH-10886038 · Data updated 2026-11-12
This study is looking at how pairing therapy with medication can help people who have had weight loss surgery keep the weight off and feel better afterward.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | July 19, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $661,656 |
| NIH project number | 5R01DK125650-04 |
| Project ID | NIH-10886038 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have recently undergone metabolic and bariatric surgery and are seeking additional support to maintain their weight loss.
✕Less likely to help
Patients who have not had metabolic and bariatric surgery or those who are not struggling with weight management post-surgery may not benefit from this research.
What this research studies
This research investigates how combining behavioral therapies with pharmacological treatments can enhance weight loss outcomes for individuals who have undergone metabolic and bariatric surgery (MBS). It aims to address the common issue of weight regain after surgery by exploring effective treatment options that can be implemented in the aftercare phase. The study will involve rigorous randomized controlled trials to assess the effectiveness of these combined approaches, providing valuable insights into optimal post-surgery care.
Why it matters
Potential benefit: If successful, this research could lead to improved long-term weight management and health outcomes for patients who have undergone bariatric surgery.
How similar studies have gone: While there is limited research on the combined effects of pharmacological and behavioral treatments post-MBS, this approach is innovative and aims to fill a significant gap in existing literature.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Ivezaj, Valentina — Yale University
- Study coordinator: Ivezaj, Valentina
Related research
Other NIH-funded projects on the same topics.
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Comparing medicines and weight-loss surgery for liver disease linked to metabolic problems
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Decoding how bariatric surgery changes brain signals to help weight loss
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BREW ME Model: How bariatric surgery changes alcohol use biology
A study investigates why some people drink more or develop hazardous drinking after bariatric surgery, using biology and behavior to understand the change.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.