Condition

Obesity & Overweight clinical trials and research

• 116Clinical trials
• 6New in 30 days
• 34Countries

Newest Obesity & Overweight clinical trials

All recruiting trials (116)

• How incretin treatments affect muscle mass and function in people with overweight or obesity

  This study will see how drugs like semaglutide and tirzepatide influence fat-free mass, muscle strength, and physical function in adults with overweight or obesity.

  Recruiting Radboud University Medical Center · Amsterdam and 1 other locations · NCT07929831

• Dose find for remimazolam plus alfentanil for gastroscopy in obese adults

  This trial tests what dose of remimazolam besylate with alfentanil best sedates obese adults during gastroscopy.

  Recruiting Qianfoshan Hospital · Jinan, Shandong · NCT07925684

• Two-Year Weight Loss With GLP-1 Medications Compared With Sleeve Gastrectomy in Adults

  This study compares how much weight adults lose over two years when starting GLP-1 medicines versus adults who had sleeve gastrectomy at the same center.

  Recruiting Yuzuncu Yil University · Van · NCT07901777

• Gut barrier and inflammation after fast-food overfeeding in adults

  This study tests whether 14 days of fast-food overfeeding can alter gut barrier function and trigger inflammation in adults who are generally healthy.

  Recruiting University Hospital, Gentofte, Copenhagen · Hellerup · NCT07893743

• High BMI and periodontitis in Thai adults under 60

  This study tests how common high BMI and periodontitis are among Thai adults aged 18–59 and what factors are linked to them.

  Recruiting Mahidol University · Bangkok, Ratchathewi · NCT07880717

• GLP-1 weight‑loss medicine: finding who will benefit most

  This study tests whether a GLP-1 drug called semaglutide helps with weight loss by changing eating behavior, to see which people it helps the most.

  Recruiting Phase 4 Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07870538

• Long-term Iron Absorption in Women with Overweight/Obesity vs Normal Weight

  This study tests long-term iron absorption and loss in women aged 40–50, comparing those who are overweight/obese with those of normal weight.

  Recruiting Mahidol University · Nakhon Pathom · NCT07855939

• Pistachios and post-meal metabolism in adults who are overweight or have obesity

  This study tests whether eating pistachios with a meal changes the body's glucose and insulin response in adults with overweight or obesity.

  Recruiting St. Louis University · St Louis, Missouri · NCT07853898

• Multimodal Weight Management Program for Older Adults

  A 16-week program tests whether combining resistance training, group cognitive behavioral therapy, and a high-protein diet helps adults aged 60 and older with overweight or obesity.

  Recruiting Universidade Cesumar (UNICESUMAR) · Maringá · NCT07820774

• Nitraria Retusa Infusion for Clozapine-Related Metabolic Side Effects in Treatment-Resistant Schizophrenia

  A daily Nitraria retusa leaf infusion is tested for 90 days to see if it helps with metabolic side effects in people with treatment-resistant schizophrenia who are taking clozapine.

  Recruiting Faculty of Medicine, Sousse · Sousse · NCT07817069

• Collagen Supplements After Sleeve Gastrectomy

  This observational study looks to see if taking collagen-containing supplements after sleeve gastrectomy affects muscle mass, body composition, and body image in adults who had bariatric surgery.

  Recruiting Mudanya University · Bursa, Yıldırım · NCT07809152

• Protein supplements with or without spices to protect muscle for people on GLP-1 weight loss meds

  This pilot test checks whether daily whey protein, with or without mixed spices, helps preserve muscle mass and strength in adults using GLP-1 weight-loss medicines.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07806838

• Bridge & Friends: MedDiet with Social Networks for obesity in older adults

  This study tests whether adding a social network component to a Mediterranean diet with weight loss helps older adults with obesity lose more weight and improve diet and activity.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT07798557

• High-Intensity Interval Training in Low vs Normal Oxygen for Overweight Adults Aged 50–75

  This study tests whether HIIT done under low (hypoxic) or normal oxygen conditions can reduce body fat and improve gut health in adults 50–75 who are overweight or have obesity.

  Recruiting Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques · Bellerive-sur-Allier · NCT07796971

• Ubiquinol to See if It Reduces Fatigue for Adults Using GLP-1 Weight-Loss Meds

  A daily ubiquinol supplement is tested to see if it lowers fatigue and helps keep muscle strength in adults taking GLP-1 weight-loss medicines.

  Recruiting StudySetGo · Glasgow · NCT07789106

• Alpelisib Challenge Test to measure insulin secretory capacity

  Researchers will test a new approach to measure how much insulin the body can produce in people at various weights and with or without insulin resistance, using alpelisib around a meal test.

  Recruiting Phase 1 Columbia University · New York, New York · NCT07778524

• Broadening Body Composition Diagnostics for Obesity

  This study tests how different body composition tools compare for people with obesity or overweight, to see which methods give the most accurate picture of fat and lean mass.

  Recruiting at 3 sites Foundation for the National Institutes of Health · Phoenix, Arizona and 2 other locations · NCT07776678

• Low-calorie diet with intensive lifestyle coaching to help diabetes remission in adults with Type 2 diabetes and overweight

  This study tests whether a strict low-calorie diet plus personalized lifestyle support can help adults with overweight Type 2 diabetes achieve diabetes remission more often than standard care.

  Recruiting Chulalongkorn University · Bangkok · NCT07748949

• Gestational weight gain and outcomes after preconception GLP-1 receptor agonist use

  This observational study looks to see if moms who used GLP-1 medications before pregnancy have different weight gain during pregnancy and pregnancy outcomes than those who didn’t use GLP-1 medications.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT07743567

• Impact of GLP-1 Receptor Agonist Therapy vs Structured Lifestyle on Weight and Health

  This study tests whether starting a GLP-1 receptor agonist for weight loss works differently from a structured diet-and-exercise program in improving heart and metabolic health for adults with overweight or obesity.

  Recruiting Texas Tech University · Lubbock, Texas · NCT07740291

• One Year of Intensive Lifestyle Treatment for Children with ISO-BMI Over 30 and Their Families

  This trial tests a year-long intensive lifestyle program for kids aged 10–16 with ISO-BMI of 30 or higher, and also involves their families.

  Recruiting Tampere University Hospital · Tampere, Pirkanmaa · NCT07738029

• Topical-Lingual Semaglutide for Obesity in Adults

  This study tests a topical-lingual liquid form of semaglutide to help adults with obesity see if it can promote weight loss compared with the standard tablet and placebo.

  Recruiting Phase 4 Gila Therapeutics, Inc. · Minneapolis, Minnesota · NCT07728383

• Inulin Prebiotic for Perimenopausal Women with Overweight or Obesity

  This study tests whether 2 weeks of inulin can affect gut and vaginal microbes, heart health, and muscle health in perimenopausal women who are overweight or obese, using a crossover design.

  Recruiting George Washington University · Washington D.C., District of Columbia · NCT07724522

• Family-based weight wellness with medically tailored groceries and group visits

  We’re testing a family-focused program that uses group medical visits and medically tailored groceries to help kids 12–17 with overweight or obesity, along with their parents.

  Recruiting at 2 sites Tufts University · Boston, Massachusetts and 1 other locations · NCT07717658

• Myokines in metabolic and endocrine diseases linked to sarcopenia

  This study tests whether myokines can serve as biomarkers or drivers of sarcopenia and sarcopenic obesity in people with metabolic or endocrine diseases.

  Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Woluwe-Saint-Pierre - Sint-Pieters-Woluwe · NCT07703683

• Kodo Millet Porridge and Gut Health in Overweight and Obese Adults

  This study tests whether daily intake of Kodo millet porridge for 12 weeks can improve gut bacteria and metabolic health in adults who are overweight or obese.

  Recruiting Jss Medical College, Jss Academy of Higher Education and Research · Mysore, Karnataka · NCT07703371

• How GLP-1 meds affect resistance training in adults with obesity/diabetes

  This study tests whether adults taking a GLP-1 receptor agonist can better preserve or gain muscle when they do resistance training.

  Recruiting Ohio State University · Columbus, Ohio · NCT07702461

• Lumateperone for Bipolar Depression with Obesity: Effects on Mood and Brain Aging

  This trial tests whether lumateperone helps mood symptoms in adults with bipolar depression and obesity, and whether it affects inflammation and brain aging markers over about 6 weeks.

  Recruiting Phase 4 Massachusetts General Hospital · Boston, Massachusetts · NCT07699445

• Body composition changes with obesity medications, with or without exercise

  This study tests whether adding cardiovascular or resistance exercise to obesity meds helps preserve lean body mass in adults taking obesity drugs.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT07698145

• Taiwan green propolis for MASLD and lipid/metabolic issues

  This study tests whether Taiwan green propolis capsules can improve blood lipids and body fat in adults with MASLD compared to a placebo over 12 weeks.

  Recruiting Taipei Medical University · Dalin · NCT07692438

• How the body handles sugar after meals in people who are lean or have obesity

  This study tests how a high- versus low-glycaemic meal affects the body's processing of glucose in healthy adults, comparing those who are lean to those with obesity.

  Recruiting Wageningen University · Wageningen · NCT07690176

• Real-Time Glucose Monitoring in Newly Diagnosed Type 2 Diabetes

  This study tests whether real-time glucose monitoring helps people with newly diagnosed type 2 diabetes manage glucose better than traditional finger-prick testing.

  Recruiting at 2 sites Bogomolets National Medical University · Kyiv and 2 other locations · NCT07690163

• Dramatherapy Added to Physical Activity for Obesity Care

  This trial tests whether adding dramatherapy to a standard adapted physical activity program helps adults with obesity in bariatric or medical care improve psychosocial well‑being and weight-related outcomes.

  Recruiting Universite du Littoral Cote d'Opale · Blendecques, Hauts-de-France · NCT07685483

• Orally Taken TIX100 in Healthy Overweight/Obese Adults

  This study will test whether daily oral TIX100 is safe and well tolerated in healthy adults who are overweight or obese.

  Recruiting Phase 1 TIXiMED, Inc. · Chula Vista, California · NCT07675590

• Cooking classes for families to help with weight loss in Abu Dhabi

  This program tests whether healthy home-cooked meals made by trained home cooks can help Emirati adults with overweight or obesity lose weight and eat better.

  Recruiting Institute for Healthier Living Abu Dhabi · Abu Dhabi · NCT07675148

• Time-restricted eating after bariatric surgery

  This study tests whether a 16:8 eating window helps adults with obesity, including those who have had bariatric surgery, see weight or metabolic improvements.

  Recruiting at 2 sites Medipol University · Bursa, Lütfen Seçiniz. and 1 other locations · NCT07672821

• Dietary changes to help adults with Type 1 diabetes and overweight see if moderate carbs, time-restricted eating, or regular calories work

  We’re testing three weight-loss approaches in adults with type 1 diabetes who are overweight or obese to see which helps reduce weight safely.

  Recruiting Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud · Málaga, Málaga · NCT07667504

• Spermidine supplement for lipid and weight changes in adults with obesity and high cholesterol

  This study tests whether taking spermidine daily for 1 month can improve blood lipids and body weight in adults who are overweight or obese with high cholesterol, while monitoring safety.

  Recruiting Shanghai 10th People's Hospital · Shanghai, Shanghai Municipality · NCT07662330

• Mazdutide and coronary plaque in people with coronary artery disease and overweight or obesity

  This study tests whether mazdutide can slow or reduce coronary plaque build-up in adults with coronary artery disease who are overweight or obese.

  Recruiting Phase 4 China National Center for Cardiovascular Diseases · Beijing, Beijing Municipality · NCT07657676

• CX11 tablets: testing safe doses for obesity and weight-related conditions

  This study tests different doses of CX11 tablets to see if they are safe and tolerable in adults with obesity or overweight and related health issues.

  Recruiting at 2 sites Phase 1 Corxel Pharmaceuticals · Las Vegas, Nevada and 1 other locations · NCT07652047

• Genetic, Microbiome, and Behavioral Factors in Obesity

  This study will test whether genetic, gut microbiome, and behavioral factors affect how people tolerate, adhere to, and respond to a dual GLP-1/GIP medicine for obesity.

  Recruiting at 2 sites Jan Kochanowski University · Krakow and 1 other locations · NCT07650149

• Hydration Support to Help GLP-1 Therapy Side Effects

  This 17-week program tests whether boosting hydration in people starting GLP-1 receptor agonist therapy can lessen side effects and help people continue treatment.

  Recruiting State University of New York at Buffalo · Buffalo, New York · NCT07641361

• Explainable AI helps families manage obesity in kids and young adults with diabetes or asthma

  This study tests a family-centered digital program to help adolescents and young adults with overweight or obesity, including those with Type 1 diabetes or asthma, see if the program improves wellbeing and healthy habits over 3 months.

  Recruiting Adhera Health, Inc. · Seville · NCT07638345

• Eating patterns before, during, and after obesity medication in adults with obesity

  This study will see how eating habits change over 18 months for adults with obesity who are taking obesity medications as part of routine care.

  Recruiting University College Dublin · Dublin · NCT07636395

• Lifestyle program to improve sleep and health for night shift workers

  This program tests a combined lifestyle plan to improve sleep, habits, and overall health in adults who regularly work night shifts.

  Recruiting at 3 sites Wageningen University · Bremen and 4 other locations · NCT07631767

• Transcutaneous auricular vagus nerve stimulation plus lifestyle for poor weight-loss responders

  This study tests whether adding taVNS to lifestyle changes helps overweight or obese adults who lost at most 5% weight after 12 weeks of diet and exercise.

  Recruiting The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu · NCT07630597

• Transcutaneous auricular vagus nerve stimulation added to tirzepatide for poor weight loss responses

  This study tests whether adding taVNS to tirzepatide helps overweight or obese people who have not lost more than 10% of their weight after 12 weeks of tirzepatide.

  Recruiting The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu · NCT07619989

• Gastric Fundal Treatment Plus Antral Myotomy for Weight Loss in Obesity

  This study tests GFMA plus BEAM to see if they help people with obesity lose weight.

  Recruiting Phase 2 Cairo University · Cairo · NCT07612527

• Sevoflurane vs. Propofol for anesthesia in obese adults undergoing lumbar surgery

  In adults with obesity undergoing lumbar instrumentation, this study tests whether sevoflurane inhaled anesthesia or propofol IV anesthesia affects inflammatory markers after surgery.

  Recruiting Ataturk University · Erzurum · NCT07611240

• Real-time glucose monitoring to help people with prediabetes see if their lifestyle changes work

  This study tests whether using real-time continuous glucose monitoring helps adults with prediabetes improve blood sugar control and stick to lifestyle changes better than traditional self-monitoring over 3 months.

  Recruiting at 2 sites Bogomolets National Medical University · Kyiv and 2 other locations · NCT07599072

• Center-based childcare to help preschoolers from low-income families avoid unhealthy weight gain in summer

  This study tests whether sending preschoolers from low-income homes to center-based childcare during the summer helps prevent unhealthy weight gain.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT07583459

• Personalized 26-week program to help keep weight off

  This 26-week program tests whether tailored messages, weekly check-ins and weighing, and optional health coaching help adults who recently lost at least 7% of their weight keep it off.

  Recruiting University of Utah · Salt Lake City, Utah · NCT07577765

• Do different fish oils lower diabetes risk factors in people at high risk

  This study tests whether EPA or DHA fish oil works better than corn oil at improving markers linked to type 2 diabetes in adults who are at high risk.

  Recruiting Phase 2 Institut de Recherches Cliniques de Montreal · Montreal, Quebec · NCT07575438

• ERX1000 for obesity in adults

  This study tests whether an oral drug called ERX1000 is safe and tolerable in adults with obesity or overweight.

  Recruiting at 3 sites Phase 2 ERX Pharmaceuticals · Louisville, Kentucky and 2 other locations · NCT07570758

• Safety-first test of DWRX5003 and related compounds in healthy adults

  This early-phase study tests whether DWRX5003 and its related compounds are safe and how they behave in the body of healthy adults.

  Recruiting Phase 1 Daewoong Pharmaceutical Co. LTD. · Seoul · NCT07539415

• Using Native Hawaiian cultural values to strengthen youth resilience, health, and well-being

  This project will try a community referral program that connects Native Hawaiian and Pacific Islander youth ages 12–25 to culture-based Kaiona programs to see if it improves mental health and chronic conditions like asthma and obesity.

  Recruiting Waianae Coast Comprehensive Health Center · Waianae, Hawaii · NCT07536256

• Bambú multicomponent early parenting program to prevent childhood obesity in vulnerable families

  This program tests whether the Bambú multicomponent early parenting intervention in primary care can help prevent excess weight in children aged 6 months to 3 years from vulnerable families where at least one parent has overweight or obesity.

  Recruiting at 3 sites Avedis Donabedian Research Institute · Burgos, Castille and León and 3 other locations · NCT07529704

• Single infrared sauna session for blood sugar control in adults with overweight

  This tests whether a single 40-minute infrared sauna session before a meal can lower post-meal blood sugar and improve 24-hour glucose control in adults who are overweight.

  Recruiting University of Prince Edward Island · Charlottetown, Prince Edward Island · NCT07520929

• Xanthigen for weight loss and metabolic health in adults with overweight

  This 16-week randomized, triple-blind test will see if taking a daily Xanthigen capsule (300 mg or 600 mg) helps adults aged 20–50 with BMI 27–29.9 lose weight and improve metabolic blood tests compared with a placebo.

  Recruiting Universidad Católica San Antonio de Murcia · Murcia, Murcia · NCT07519980

• How body fat, muscle, and metabolism differ after childhood versus adult-onset obesity

  This study will test whether adults who became obese as children have different fat, muscle, and metabolism features than adults who became obese later, using biopsies, scans, exercise tests, and a targeted weight-loss program.

  Recruiting at 2 sites Concordia University, Montreal · Montreal, Quebec and 1 other locations · NCT07515547

• How pancreatic polypeptide affects amylin-driven fullness in healthy adults

  This test will see if giving pancreatic polypeptide together with amylin changes feelings of fullness and how much healthy adults eat.

  Recruiting University Hospital, Gentofte, Copenhagen · Hellerup, Capital Region · NCT07506369

• Transit bipartition using a metallic anastomotic clip and circular fundocorporeal gastroplication

  This trial tries a new metallic anastomotic clip to create a second stomach-to-ileum pathway to help adults with type 2 diabetes and BMI 25–34.9 improve blood sugar control.

  Recruiting The Society of Bariatric and Metabolic Surgeons of Kazakhstan · Astana · NCT07495020

• Frequency of MAFLD and its links to nutrition and metabolic risk in rural Bangladesh

  This project will see how common MAFLD is and whether nutritional status and metabolic risk factors are linked among adults living in a rural area of Bangladesh.

  Recruiting Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Dhaka · NCT07470749

• Lifestyle program to prevent obesity and eating disorders in transgender and gender-diverse adolescents

  This project will test whether a 6-month gender-affirming lifestyle program with monthly group sessions for adolescents and caregivers plus weekly support messages helps transgender and gender-diverse 10–14-year-olds prevent obesity and eating disorders and improve quality of life.

  Recruiting University of Sao Paulo · São Paulo, São Paulo · NCT07466069

• Pediatric referrals to summer day camps to help children from low-income families with overweight or obesity

  This project will try referring Medicaid-insured children who are overweight or obese to summer day camps to see if camp participation is a feasible and acceptable way to reduce summer weight gain.

  Recruiting University of Central Florida · Orlando, Florida · NCT07464015

• Keeping muscle and strength during tirzepatide weight loss with resistance exercise

  This program will test whether adding a progressive resistance exercise program to tirzepatide helps overweight or obese women aged 25–50 keep muscle and physical function while losing weight.

  Recruiting University of Exeter · Exeter, Devon · NCT07457437

• Integrated Traditional Chinese and Western medicine care for adults with obesity

  This project will try combining traditional Chinese medicine and Western medical care in adults with obesity to see how well that combination works in everyday clinical practice.

  Recruiting Hubei Hospital of Traditional Chinese Medicine · Wuhan, Hubei · NCT07448090

• Combining the biologic ixekizumab with the weight-loss drug tirzepatide for people with psoriatic arthritis and overweight/obesity

  This trial will test whether ixekizumab, tirzepatide (a weight-loss drug), or both together change skin, joint, and fat tissue in adults with psoriatic arthritis who are overweight or obese.

  Recruiting NHS Greater Glasgow and Clyde · Birmingham, England and 3 other locations · NCT07443956

• Akkermansia muciniphila plus berberine to improve insulin sensitivity in night-shift workers

  This trial tests whether taking Akkermansia muciniphila together with berberine can improve insulin sensitivity in people who work regular night shifts and have overweight or prediabetes.

  Recruiting FH Joanneum Gesellschaft mbH · Graz, Styria · NCT07440147

• Personalized exercise and diet program to reduce atrial fibrillation episodes and heart/body fat

  This 12-month program will try personalized exercise plus dietary counseling to reduce atrial fibrillation episodes, symptoms, and heart and body fat in overweight adults with paroxysmal or persistent AF.

  Recruiting University of Eastern Finland · Jyväskylä, Central Finland and 3 other locations · NCT07430007

• 5-week combined aerobic and strength exercise after bariatric surgery

  This test tries a 5-week combined aerobic and strength exercise program for adults recovering from sleeve gastrectomy or gastric bypass to see if it improves muscle quality, body composition, physical function, and quality of life.

  Recruiting Universidad Autónoma de Chile · Santiago, Santiago Metropolitan · NCT07423780

• Artichoke by-product supplement with an energy-restricted Mediterranean diet to prevent type 2 diabetes

  This trial tests whether taking daily artichoke-derived capsules together with an energy-restricted Mediterranean diet can help adults with overweight or obesity and insulin resistance improve blood sugar control and lose weight.

  Recruiting Clinica Universidad de Navarra, Universidad de Navarra · Pamplona, Navarre · NCT07415720

• Which patients are offered and start prescription medicines for obesity

  This project will see which people offered prescription medicines for overweight or obesity accept them and how those who start treatment do over time.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bologna · NCT07414043

• Using REMS ultrasound to check bone density in children and teens with conditions that lower bone strength

  This project will test whether REMS, a radiation-free ultrasound method, can measure bone mineral density in children and adolescents aged 5–18 who have conditions that weaken their bones.

  Recruiting Meyer Children's Hospital IRCCS · Florence, Tuscany · NCT07412782

• Incretin-based Therapy Plus a Structured Lifestyle Plan for Obesity

  This study tests whether adding a six-month supervised exercise and nutrition program to prescribed incretin-based weight‑loss medication helps preserve muscle and physical function in adults with obesity, compared with medication alone.

  Recruiting Laval University · Québec, Quebec and 1 other locations · NCT07409831

• Exercise to lower blood fats and improve blood-vessel health in young people with obesity

  This study will test whether adding a structured exercise program to the Healthworks! weight-loss program helps lower blood fat levels and improve blood-vessel function in 10–20-year-olds with obesity.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07409064

• Predicting Weight Loss After Obesity Treatments

  This study tests what factors predict how much weight people lose after either obesity medications or bariatric surgery.

  Recruiting Université Catholique de Louvain · Brussels, Brussels Capital · NCT07402031

• Semaglutide plus topical steroid/calcipotriol for plaque psoriasis in adults with overweight, obesity, or type 2 diabetes

  This trial will test whether taking oral semaglutide along with a topical steroid/calcipotriol cream improves skin symptoms and reduces metabolic inflammation in adults with plaque psoriasis who are overweight, obese, or have type 2 diabetes.

  Recruiting Phase 4 Hospital Universitario Dr. Jose E. Gonzalez · Monterrey, N.L. · NCT07401992

• Food support plus one-on-one behavioral weight-loss program for adults with obesity and food insecurity

  This trial will test whether adding home-delivered groceries or grocery vouchers to a one-on-one behavioral weight-loss program helps adults with obesity who face food insecurity lose more weight.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07396805

• Can a special medical nutrition product help keep muscle during GLP-1 weight-loss treatment?

  This trial tests whether Myosave®, a medical nutrition product, helps adults with overweight or obesity who are starting GLP‑1 or dual GIP/GLP‑1 weight‑loss medications keep appendicular skeletal muscle mass during 24 weeks of treatment.

  Recruiting at 3 sites Pharmanutra S.p.a. · Milan and 2 other locations · NCT07393360

• Tongue ultrasound for children and teens with obesity

  For children and teens with obesity enrolled in a 30-week inpatient weight-loss program, this project uses ultrasound to see if tongue size, fat content, and stiffness relate to body measurements and sleep apnea and change after the program.

  Recruiting Haute Ecole Bruxelles-Brabant · Brussels and 1 other locations · NCT07370350

• Scalp hair chemical changes in people with severe obesity and after bariatric surgery

  This project will see if chemicals trapped in scalp hair change with body weight and can signal hair thinning or muscle loss in adults having bariatric surgery.

  Recruiting Singapore General Hospital · Singapore · NCT07368842

• Standard care versus weight loss with tirzepatide for obesity-related high blood pressure in young adults

  This project will test whether weight loss achieved with tirzepatide lowers blood pressure more than usual care in 18–40-year-olds who are overweight and have hypertension.

  Recruiting Cambridge University Hospitals NHS Foundation Trust · Cambridge, Cambridgeshire · NCT07364175

• Five weight‑neutral online programs to support healthy eating, activity, and body appreciation for adults with higher body weight

  This project will test five different online group programs that combine Mediterranean‑style eating, physical activity guidance, mindful eating, body acceptance, and enjoyable exercise for adults with BMI 25–40 to see which programs people like and stick with.

  Recruiting The Miriam Hospital · Providence, Rhode Island · NCT07363616

• Ketone supplements and insulin sensitivity in overweight older adults

  This study will test whether an oral ketone supplement, given with or without growth hormone, can improve insulin sensitivity and energy use in overweight adults aged 55–70.

  Recruiting University of Aarhus · Aarhus N · NCT07359625

• Improving Cervical Cancer Prevention for Women with Chronic Conditions

  We’re testing PINPOINT, a patient-navigation and self-collection approach, to see if it helps women with obesity or type 2 diabetes who aren’t up-to-date with cervical cancer screening get screened.

  Recruiting University of Florida · Gainesville, Florida · NCT07351110

• Long-term changes in skeletal muscle after mixed HIIT training in adults with overweight or obesity

  This study tests whether a 6-month hybrid HIIT program improves body composition, fitness, and muscle health in adults with overweight or obesity who follow a balanced diet.

  Recruiting University of Thessaly · Trikala, Thessaly · NCT07341711

• Empagliflozin for metabolic health in adults with HIV on dolutegravir

  This trial tests whether the diabetes medicine empagliflozin can help reduce obesity-related metabolic problems in adults living with HIV who are taking dolutegravir-based antiretroviral therapy.

  Recruiting Phase 2 Cairo University · Cairo · NCT07336797

• Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

  A 24-week program tests whether a food-as-medicine approach (FIM+DASH) helps adults with hypertension and obesity lower blood pressure and improve eating patterns compared with usual care.

  Recruiting Phase 2 University of Illinois Chicago · Chicago, Illinois and 3 other locations · NCT07332741

• Breath mass spectrometry test to distinguish metabolic syndrome and metabolically healthy obesity

  This project will test whether a breath mass spectrometry test can tell apart adults with metabolic syndrome, adults with metabolically healthy obesity, and healthy-weight adults.

  Recruiting I.M. Sechenov First Moscow State Medical University · Moscow · NCT07330297

• Tirzepatide for improving reproductive function and metabolic health in overweight women with PCOS

  We will test whether tirzepatide can improve menstrual regularity and metabolic health in premenopausal women with PCOS who are overweight or have obesity.

  Recruiting Phase 4 University of Bonn · Bochum and 1 other locations · NCT07326111

• NTU JO-SMART Program for Obesity and Knee Osteoarthritis

  A program that combines AI-guided community exercise with continuous glucose monitoring to help people who are overweight and have knee OA see if it improves blood sugar and joint health.

  Recruiting at 2 sites National Taiwan University Hospital · Taipei, Taiwan and 1 other locations · NCT07317310

• Side-to-side duodeno-ileostomy with magnets versus semaglutide for adults with obesity and type 2 diabetes

  This trial tests whether a magnet-assisted side-to-side duodeno-ileostomy surgery or the medication semaglutide works better to improve blood sugar control and weight in adults with obesity and type 2 diabetes.

  Recruiting GT Metabolic Solutions, Inc. · Westmount, Quebec · NCT07317115

• Pediatric Healthy Weight Index at Stanford

  This project will test whether a simple score made from wearable activity trackers, continuous glucose monitors, and lab tests can show how well children and teens with obesity use insulin and their overall heart and metabolic health while they start surgery or GLP‑1 therapy.

  Recruiting Stanford University · Palo Alto, California · NCT07316816

• Exercise effects on blood vesicles and fitness in adults with overweight or obesity

  This project will test whether high-intensity interval treadmill exercise changes small particles in the blood (extracellular vesicles) and improves physical fitness in Thai adults aged 25–45 with overweight or obesity.

  Recruiting Mahidol University · Mueang Samut Prakan · NCT07312344

• Respiratory function and inspiratory muscle training for adults with obesity

  This will test whether inspiratory muscle training can improve breathing and lower inflammation in adults aged 30–60 with obesity (BMI ≥30).

  Recruiting Wroclaw University of Health and Sport Sciences · Wroclaw, Dolny Śląsk · NCT07307417

• High-intensity interval exercise to improve vitamin D levels in adults with overweight or obesity

  This trial will try three hybrid high-intensity interval sessions per week for 12 weeks to see if exercise increases vitamin D (25(OH)D) in adults with overweight or obesity during winter.

  Recruiting University of Thessaly · Trikala, Karyes · NCT07300332

• Different weekly feedback messages to support weight loss

  This project will test whether different weekly feedback messages delivered via a smartphone app help adults with overweight or obesity lose weight.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT07292389

• Digestion and gut function after bariatric surgery

  This project will test how digestion — including enzymes, bile acids, pH, and transit time — works in adults with obesity and in people at least one year after Roux‑en‑Y or sleeve gastrectomy by collecting intestinal samples and using a swallowable sensor capsule.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07286968

• HDM1005 for non-diabetic Chinese adults with overweight or obesity

  This trial will test whether once-weekly HDM1005 helps Chinese adults who are overweight or have obesity but do not have diabetes lose weight and remain safe over one year.

  Recruiting Phase 3 Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · Shanghai · NCT07279194

• Waiting on Atrial Fibrillation Intervention Therapy: Weight loss before ablation

  This trial tests whether adding weekly semaglutide before first-time AF ablation helps people who are overweight or obese have better rhythm outcomes.

  Recruiting Phase 4 Karolinska University Hospital · Stockholm · NCT07275697

• Saffron (Crocus sativus) tepal water extract for lowering meal-time blood sugar in obesity and prediabetes

  This study tests whether drinking a cold water extract made from saffron tepals before a meal can lower blood sugar after eating in adults with obesity or prediabetes.

  Recruiting Early Phase 1 University of Primorska · Izola · NCT07261475

• Combining genetics, blood, urine, and stool data to predict complications of metabolic syndrome

  The team will try combining genetic, blood, urine, and stool data to see if patterns predict complications in adults with or without metabolic syndrome.

  Recruiting Chang Gung Memorial Hospital · Taoyuan · NCT07248371

• Six-month sirtuin activator supplementation for women with overweight or obesity

  This test will see if taking a daily sirtuin activator supplement for six months improves metabolism in women aged 40–65 with overweight or obesity.

  Recruiting Poznan University of Life Sciences · Poznan · NCT07245979

• Daily peanuts for fullness, diet quality, and body composition

  This study will test whether eating peanuts every day for 12 weeks helps adults taking GLP‑1 medicines feel fuller, have more energy, and improve weight and body composition.

  Recruiting University Hospitals Cleveland Medical Center · Clevland, Ohio · NCT07244458

• Daily pistachios for people taking GLP-1 weight-loss medicines

  This 12-week test will see if eating pistachios every day helps adults on GLP-1 medicines feel fuller, have more energy, and improve weight and diet quality.

  Recruiting University Hospitals Cleveland Medical Center · Clevland, Ohio · NCT07244445

• How GLP‑1 weight‑loss medicines affect taste and eating habits

  This project sees if adults with obesity who take GLP‑1 drugs for at least 12 weeks notice changes in taste, food preferences, and eating habits.

  Recruiting at 3 sites San Raffaele Telematic University · Roma, Italy and 3 other locations · NCT07229170

• GLOBE registry to develop severity, quality-of-life, and cost tools for people with BMI over 25

  This project will create tools to measure severity, quality of life, and the costs of living with a BMI over 25 using input from adults and clinicians.

  Recruiting Medialis Ltd. · Milton Keynes · NCT07229027

• Optimizing lower-burden ways to track eating and weight during an online weight-loss program

  This project will test five different, lower-burden ways of tracking eating and weight to see which help adults with overweight or obesity stick with a 24-week online weight-loss program.

  Recruiting The Miriam Hospital · Providence, Rhode Island · NCT07228130

• Weekly self-monitoring feedback and goal prompts to support weight loss

  This trial will test different weekly feedback messages and goal prompts delivered by smartphone to see which help adults with overweight or obesity stick to tracking their diet, activity, and weight and lose more weight.

  Recruiting Wake Forest University Health Sciences · Milwaukee, Wisconsin · NCT07227051

• Personalized daily step targets to change body fat and cardiometabolic risk in adults with overweight or obesity

  This project will test if giving personalized daily step targets based on body fat helps adults with overweight or obesity change body composition and lower cardiometabolic risk.

  Recruiting Kennesaw State University · Kennesaw, Georgia · NCT07221279

• FELLAship program to improve heart and metabolic health in Black men

  This program will try a 24-week, church-based combination of exercise and health education to see if it improves blood pressure, cholesterol, blood sugar, and weight for Black men age 18 and older in the Birmingham area.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT07220213

• How higher body mass index affects teens' braces, gums, and tooth health.

  This project will test whether adolescents with higher BMI have more gum inflammation, tooth discoloration, and oral bacteria while wearing fixed braces.

  Recruiting University of Rochester · Rochester, New York · NCT07217756

• Semaglutide effects on visceral fat and liver in people with chronic kidney disease

  This project will see if people with type 2 diabetes and chronic kidney disease who take semaglutide have less belly and liver fat than similar people not taking the drug.

  Recruiting University of Alberta · Edmonton, Alberta · NCT07187830

• Home-based tDCS for cognitive problems in breast cancer survivors with and without obesity

  This will test whether home-based transcranial direct current stimulation (tDCS) can improve cancer-related memory, attention, or processing speed problems in breast cancer survivors and whether obesity changes the effect.

  Recruiting University of Helsinki · Helsinki, Uusimaa · NCT07112521

• Exploring the benefits of Bottarga supplementation for prediabetes

  This study is testing if adding Greek Bottarga to the diet can help overweight people with prediabetes improve their metabolic health compared to a similar dairy product.

  Recruiting Cambridge Health Alliance · Sommerville, Massachusetts · NCT06988462

Related topics

Quick answers

How many Obesity & Overweight clinical trials are recruiting right now?

116, as of November 12, 2026. 6 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 34 countries. The most sites are in United States (36 trials), China (7 trials), Canada (6 trials), Spain (5 trials), United Kingdom (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 7, Phase 2: 5, Phase 1: 4, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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