Supervised exercise after bariatric surgery to protect muscle and bone
Official title: CLINICAL TRIAL ON THE EFFECT OF SUPERVISED PHYSICAL EXERCISE AFTER BARIATRIC SURGERY ON MUSCLE MASS AND BONE DENSITY (OBEFIT STUDY)
Run by Hospitales Universitarios Virgen del Rocío · NCT07324447 · Data updated 2026-11-12
This program tests whether supervised exercise after gastric bypass or sleeve surgery helps preserve muscle mass and bone density in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Hospitales Universitarios Virgen del Rocío Academic / other |
| Locations | 2 sites (Seville, Sevilla and 1 other locations) |
| Status | Recruiting |
| Started | February 1, 2026 |
| Main results expected | December 1, 2027 |
| Study ends | November 1, 2028 |
| Registry record updated | January 8, 2026 |
| Trial ID | NCT07324447 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) scheduled for gastric bypass or sleeve at Hospital Universitario Virgen del Rocío who are medically cleared for exercise and can travel within 60 km or 45 minutes to Pablo de Olavide University.
✕Probably not a fit
Patients with conditions affecting bone health, those heavier than 150 kg, on dialysis, cancer survivors, or living beyond the distance limit may be excluded or unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults listed for bariatric surgery at Hospital Universitario Virgen del Rocío will follow either a supervised postoperative physical exercise program or usual care without a structured exercise program. Investigators will measure muscle mass and bone mineral density by densitometry and evaluate muscle function with handgrip testing. Secondary measures include body composition, maximal fat oxidation, resolution of type 2 diabetes and hypertension, and quality of life. Assessments occur over the postoperative follow-up period to compare outcomes between groups.
Why it matters
Potential benefit: If successful, the supervised exercise program could reduce postoperative losses of muscle and bone, improve physical function, and enhance metabolic and quality-of-life outcomes.
How similar studies have gone: Prior studies often show supervised exercise preserves muscle mass and improves fitness after bariatric surgery, but evidence that it prevents bone mineral density loss is limited and mixed.
Who can join: the full rules
Show full inclusion / exclusion criteria
INCLUSION CRITERIA Patients who are on the waiting list for bariatric surgery (gastric bypass or sleeve) at the Hospital Universitario Virgen del Rocío in Seville, in addition to: * Be 18 years of age or older. * Suitable for physical exercise. * Signature of informed consent. EXCLUSION CRITERIA. * Body weight greater than 150kg. * Distance from the place of residence to the Pablo de Olavide University in Seville greater than 60 km or 45 minutes by car. * Having any of the following conditions: lipedema, cancer survivors, metabolic bone diseases, consumption of medication or presence of pathology that affects bone health. * Patients undergoing dialysis.
Where it's running
-
Hospital virgen del rocio
Seville, Sevilla, Spain Recruiting -
Universidad Pablo de Olavide
Seville, Sevilla, Spain Recruiting
Study contacts
- Study coordinator: Isaias Alarcon, MD PhD
- Email: isaiasalarcon@gmail.com
- Phone: +34646357875
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.